Protein Alignment Pvf1 and PDGFA

DIOPT Version :9

• Sequence 1: NP_523407.1
• Gene: Pvf1 / 32876
• FlyBaseID: FBgn0030964
• Length: 325
• Species: Drosophila melanogaster
• Sequence 2: XP_011513717.1
• Gene: PDGFA / 5154
• HGNCID: 8799
• Length: 256
• Species: Homo sapiens
• Alignment Length: 184
• Identity: 46/184 - (25%)
• Similarity: 68/184 - (36%)
• Gaps: 43/184 - (23%)

  Fly    68 QADDPSAAPG-------ALEGSC-CQGAAAEAGTPLTLPLSVSAELTNVTADYDVSGEMPSSKEN 124
            |...|.|.||       :|:.|. ..|..|....|...||.:..
Human    86 QHPGPPATPGDRLRSEDSLDTSLRAHGVHATKHVPEKRPLPIRR--------------------- 129

  Fly   125 FKRSIMKSTVRNATPASCSPQPTIVELKPPAED--EANYYYMPACTRISRCNGCCGSTLISCQPT 187
             ||||     ..|.||.|..:..|.|:.....|  .||:...|.|..:.||.|||.::.:.|||:
Human   130 -KRSI-----EEAVPAVCKTRTVIYEIPRSQVDPTSANFLIWPPCVEVKRCTGCCNTSSVKCQPS 188

  Fly   188 EVEQVQLRVRKVDRAATSGRRPFTIITVEQHTQCRCDCRTKAEDCNVYQSYRKD 241
            .|....::|.||:......:.....:.:|:|.:|.|...:...|      ||::
Human   189 RVHHRSVKVAKVEYVRKKPKLKEVQVRLEEHLECACATTSLNPD------YREE 236

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pvf1	NP_523407.1	PDGF	142..223	CDD:278756	23/82 (28%)
PDGFA	XP_011513717.1	PDGF_N	<101..140	CDD:282538	13/65 (20%)
		PDGF	139..226	CDD:197537	25/86 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165148526
Domainoid	1	1.000	57	1.000	Domainoid score	I10898
eggNOG	1	0.900	-	-		E1_2C4GD
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm42132
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11633
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4285
SonicParanoid	1	1.000	-	-		X1138
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	9	8.830