DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pvf1 and pdgfa

DIOPT Version :9

Sequence 1:	NP_523407.1	Gene:	Pvf1 / 32876	FlyBaseID:	FBgn0030964	Length:	325	Species:	Drosophila melanogaster
Sequence 2:	XP_031748295.1	Gene:	pdgfa / 100038202	XenbaseID:	XB-GENE-484495	Length:	225	Species:	Xenopus tropicalis

Alignment Length:	189	Identity:	47/189 - (24%)
Similarity:	78/189 - (41%)	Gaps:	37/189 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    83 CCQ-----GAAAEAGTPLTLPLSVS-----------AELTNVTADYDVSG-EMPSSKENF----- 125
            ||.     |..||....|...|:.|           .::.:|....|.|| .:.|...:|
Frog    13 CCYLSPSLGEEAEIPQELIERLAHSEIRSISDLQRLLDIDSVGGGEDASGANIRSQTRDFRHNRL 77

  Fly   126 ---KRSI---MKSTVRNATPASCSPQPTIVELKPPAED--EANYYYMPACTRISRCNGCCGSTLI 182
               |||:   .|.:|..|.||.|..:..|.|:.....|  .||:...|.|..:.||.|||.::.:
Frog    78 VPEKRSVPSRRKRSVEEAVPAICKTRTVIYEIPRSKIDSTSANFLIWPPCVEVKRCTGCCNTSSV 142

  Fly   183 SCQPTEVEQVQLRVRKVDRAATSGRRPFTIITVEQHTQCRCDCRTKAEDCNVYQSYRKD 241
            .|||:.:....::|.||:......:....::.:|:|.:|.|...:.::       ||::
Frog   143 KCQPSRIHHRSVKVAKVEYVRKKPKLKEVLVQLEEHLECTCTANSNSD-------YREE 194

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pvf1	NP_523407.1	PDGF	142..223	CDD:278756	22/82 (27%)
pdgfa	XP_031748295.1	PDGF_N	22..99	CDD:398391	18/76 (24%)
pdgfa	XP_031748295.1	PDGF	98..183	CDD:197537	23/84 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	58	1.000	Domainoid score	I10601
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm49358
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4285
SonicParanoid	1	1.000	-	-		X1138
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.030