DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7101 and CG10654

DIOPT Version :9

Sequence 1:	NP_573329.2	Gene:	CG7101 / 32875	FlyBaseID:	FBgn0030963	Length:	352	Species:	Drosophila melanogaster
Sequence 2:	NP_001261767.1	Gene:	CG10654 / 39428	FlyBaseID:	FBgn0036294	Length:	412	Species:	Drosophila melanogaster

Alignment Length:	370	Identity:	78/370 - (21%)
Similarity:	124/370 - (33%)	Gaps:	107/370 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 RLFVCPHCLTLFGEEARLERHRERKHN-DGQFLCLQCGKKYASAT-------------------F 104
            :..:|..||.|.|.:       :..|| |.:   .....||...|                   .
  Fly    36 KTMICRACLVLLGPQ-------DACHNLDSE---QDLASKYYGCTGEDAVRDLPPQLVLKSICEC 90

  Fly   105 LYRHVASWHGQQSLFYCDMCTDNCNDVKTFSGMLELQEHAEEVHRLRTLKSTASDADSQVDEMED 169
            .|:.|..:|..|.     ||.::..:.:.....:::..|..|.|....|     |..|:.:|..:
  Fly    91 CYQLVQKFHDFQR-----MCAESLRNFEKLLQDIDIGCHKLEDHTWHDL-----DTPSESNESTN 145

  Fly   170 LEMLEENIENILPSIDWDDDL-TFGWP--------------------------------TDLDKE 201
            .|     .::..|.|....:: :|.||                                .||.:|
  Fly   146 PE-----AQSHAPCIAATQEIVSFIWPQVCLPLAVILSRITLGASLEEEVYVIEDESAKQDLGQE 205

  Fly   202 SCIVNAK----------PSVFVCPFCANGFPGSLSLVRHLEQVHERSALDCCYCGKSHGSREALR 256
            ...:::|          .....|..|..||.....|..|::|........|.:|.||:.....|.
  Fly   206 KLSISSKLLGARKRRGVRHTLECRICHRGFYKPSLLEAHMQQHEGLRPYTCVHCAKSYARANLLE 270

  Fly   257 SHLQRVH-------ILLRGHVCGICQADFATADHLKKHVNSLHLDHRP-------HLCPTCGKRF 307
            |||:::|       |:   :.|..|...:.....||.|:...|..:..       |:|..|||.|
  Fly   271 SHLRQMHNNADAARII---YACPSCNKVYTANRSLKYHMRRTHERYHESESPDARHICEECGKCF 332

  Fly   308 TQRCHLTDHIKTDRGHGHG-TYTCEFCVRPFFRAIDLERHVCEEH 351
            .::.|||.| |...|...| .|.||.|.|.|:...::..|:..:|
  Fly   333 ARKAHLTRH-KMVHGSVEGRRYCCECCDRRFYTKENMVDHLLRKH 376

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7101	NP_573329.2	PHA00733	<210..263	CDD:177301	15/52 (29%)
		C2H2 Zn finger	242..263	CDD:275368	8/20 (40%)
		C2H2 Zn finger	271..292	CDD:275368	5/20 (25%)
		C2H2 Zn finger	300..319	CDD:275368	9/18 (50%)
		C2H2 Zn finger	330..347	CDD:275368	5/16 (31%)
CG10654	NP_001261767.1	zf-AD	39..115	CDD:285071	17/90 (19%)
		C2H2 Zn finger	228..248	CDD:275368	6/19 (32%)
		C2H2 Zn finger	256..313	CDD:275368	16/59 (27%)
		C2H2 Zn finger	289..314	CDD:275368	6/24 (25%)
		zf-C2H2	323..345	CDD:278523	11/22 (50%)
		C2H2 Zn finger	325..345	CDD:275368	10/20 (50%)
		C2H2 Zn finger	355..376	CDD:275368	6/20 (30%)
		C2H2 Zn finger	385..405	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45455517
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930