DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7101 and CG12942

DIOPT Version :9

Sequence 1:	NP_573329.2	Gene:	CG7101 / 32875	FlyBaseID:	FBgn0030963	Length:	352	Species:	Drosophila melanogaster
Sequence 2:	NP_610628.2	Gene:	CG12942 / 36158	FlyBaseID:	FBgn0033569	Length:	686	Species:	Drosophila melanogaster

Alignment Length:	327	Identity:	69/327 - (21%)
Similarity:	109/327 - (33%)	Gaps:	85/327 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 KKRTYHCGVC-------FAEFSRHLAAKRH------EQQCSVRVRRLFVCPHCLTLFGEEARLER 79
            |.:.:.|..|       .:|..:|| ...|      |..|.::..    ||.|..:|.::....:
  Fly   341 KNQNFKCRPCNSYETKDRSEMQKHL-IDHHKIDGDFEMYCYMQAN----CPACDRIFKDQRSARK 400

  Fly    80 HRERKHNDGQ--------FLCLQCGKKYASATFLYRHVASWHGQQ------SLFYCDMCTDNCND 130
            |..|.|...|        :.|..|.|       ::...||.|..|      .:.:|..|....|.
  Fly   401 HYTRVHTPVQIAVSPTESYACTACDK-------VFNQKASLHSHQRFCQVKDVVHCSFCDQQFNS 458

  Fly   131 VKTFSGMLELQE-HA-EEVHRLRTLKSTASDADSQVDEMEDLEMLEENIENILPSIDWDDDLTFG 193
            ::.:.  |.||: || |.||.....:.:...|::                           ||..
  Fly   459 MRKYE--LHLQQLHAVETVHECEICRRSFKSAET---------------------------LTMH 494

  Fly   194 WPTDLDKESCIVNAKPSVFVCPFCANGFPGSLSLVRHLEQVH-ERSALDCCYCGKSHGSREALRS 257
            .....::.          :.|..|:..:..|..|..|.|:.| ....:.|..||....:...||.
  Fly   495 RKRHSERH----------YQCGKCSLNYVNSAELRVHYERAHVNEEPVSCLTCGNQFQNMTLLRE 549

  Fly   258 HLQRVHILLRGHVCGICQADFATADHLKKHVNSLHLDHRPHLCPTCGKRFTQRCHLTDHIKTDRG 322
            |.||.|...:...|.:|..:..|....::|... |:|: |:.|..|...|..|.....|.|  :.
  Fly   550 HEQRSHQKSKVWRCEVCNFETKTRWRRRQHQYE-HMDY-PYKCQKCTSEFADRSKFRQHSK--KV 610

  Fly   323 HG 324
            ||
  Fly   611 HG 612

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7101	NP_573329.2	PHA00733	<210..263	CDD:177301	15/53 (28%)
		C2H2 Zn finger	242..263	CDD:275368	8/20 (40%)
		C2H2 Zn finger	271..292	CDD:275368	4/20 (20%)
		C2H2 Zn finger	300..319	CDD:275368	5/18 (28%)
		C2H2 Zn finger	330..347	CDD:275368
CG12942	NP_610628.2	zf-AD	22..101	CDD:285071
		C2H2 Zn finger	385..406	CDD:275368	6/20 (30%)
		C2H2 Zn finger	421..470	CDD:275368	13/57 (23%)
		C2H2 Zn finger	449..466	CDD:275371	4/18 (22%)
		C2H2 Zn finger	478..498	CDD:275368	3/46 (7%)
		C2H2 Zn finger	505..526	CDD:275368	6/20 (30%)
		C2H2 Zn finger	534..555	CDD:275368	8/20 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440070
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930