DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7101 and CG18011

DIOPT Version :9

Sequence 1:	NP_573329.2	Gene:	CG7101 / 32875	FlyBaseID:	FBgn0030963	Length:	352	Species:	Drosophila melanogaster
Sequence 2:	NP_610559.1	Gene:	CG18011 / 36068	FlyBaseID:	FBgn0033491	Length:	985	Species:	Drosophila melanogaster

Alignment Length:	417	Identity:	90/417 - (21%)
Similarity:	138/417 - (33%)	Gaps:	143/417 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 CGVCFAEFS----------RHLAAKRHEQQCSV------------------------------RV 58
            |.:|..||:          :||..::....||.                              .:
  Fly   545 CELCSREFATEATYNIHMKKHLIIEKDVHVCSTCGLLSDSRETLLAHVNSVKTACFGSKIDVELL 609

  Fly    59 RRLFVCPHCLTLFGEEARLERHRER-KHNDGQFLCLQCGKKYASATFLYRH---------VASWH 113
            |..:||.:|.:.|.|:..|:.||:. .|.||.|||..|||::.... ||||         ..|.|
  Fly   610 RDAYVCEYCSSYFKEKDCLQAHRDSGVHKDGVFLCQPCGKEFPHMK-LYRHHLRNYQQLRSDSTH 673

  Fly   114 GQQSL---FYCDM--CTD---NCNDVKTFSGMLELQEHAEEVHRLRTLKSTASDADSQVDEMEDL 170
            .:..:   :.||.  ||:   |.|.:.|              |:.||.:|.:..|:......::
  Fly   674 RRLEICVYYMCDQENCTESYVNWNSLYT--------------HKRRTHESASKQAEKSSKSAQE- 723

  Fly   171 EMLEENIENILPSIDWDDDLTFGWPTDLDKESCIVNAKPSVFV----------CPFCANGFPGSL 225
                                   |......:.|......||.|          ||.|.:.:....
  Fly   724 -----------------------WVCQFCLKECRSKMSLSVHVARSHNNDNVTCPLCNSSYKSHD 765

  Fly   226 SLVRHLEQVHERSALDCCYCGKSHGSREALRSHLQRVHILLRGHVCGICQADFATADHLKKHVNS 290
            :|.:|....||  .::|..|.|...:|....:|:..||...:.:.|.:||..|.....::.| ..
  Fly   766 ALAKHHAYWHE--PIECPECFKIVKNRRNYDTHVNVVHSNKKRYSCSVCQKGFYHKSEMEAH-QK 827

  Fly   291 LHLDHRPHLCPTCG------------------KRFTQRCHL-------TDHIKTDRGHGHG-TYT 329
            ||  .:.:.|..|.                  |||...|::       :..:||.....|| .||
  Fly   828 LH--GQSYSCEQCSFTTRNKKSLSVHVLGQHYKRFAFECNVCKKRFGRSQGLKTHMQRAHGDKYT 890

  Fly   330 CE-----FCVRPFFRAIDLERHVCEEH 351
            |.     .|.|.|..:..|..||.:.|
  Fly   891 CRDYFDGGCGRTFVNSSQLNVHVRKIH 917

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7101	NP_573329.2	PHA00733	<210..263	CDD:177301	15/62 (24%)
		C2H2 Zn finger	242..263	CDD:275368	5/20 (25%)
		C2H2 Zn finger	271..292	CDD:275368	5/20 (25%)
		C2H2 Zn finger	300..319	CDD:275368	6/43 (14%)
		C2H2 Zn finger	330..347	CDD:275368	5/21 (24%)
CG18011	NP_610559.1	PRK14950	<98..>184	CDD:237864
		C2H2 Zn finger	488..508	CDD:275368
		C2H2 Zn finger	518..538	CDD:275368
		C2H2 Zn finger	545..565	CDD:275368	4/19 (21%)
		C2H2 Zn finger	575..596	CDD:275371	2/20 (10%)
		SFP1	<682..747	CDD:227516	17/102 (17%)
		C2H2 Zn finger	754..775	CDD:275368	5/20 (25%)
		C2H2 Zn finger	780..801	CDD:275368	5/20 (25%)
		C2H2 Zn finger	809..829	CDD:275368	5/20 (25%)
		C2H2 Zn finger	864..885	CDD:275368	3/20 (15%)
		C2H2 Zn finger	891..917	CDD:275368	7/25 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440071
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930