DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7101 and Zfp160

DIOPT Version :9

Sequence 1:	NP_573329.2	Gene:	CG7101 / 32875	FlyBaseID:	FBgn0030963	Length:	352	Species:	Drosophila melanogaster
Sequence 2:	NP_663458.2	Gene:	Zfp160 / 224585	MGIID:	108187	Length:	650	Species:	Mus musculus

Alignment Length:	358	Identity:	82/358 - (22%)
Similarity:	124/358 - (34%)	Gaps:	82/358 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 KRTYHCGVCFAEFSRHLAAKRHEQQCSVRVRRLFVCPHCLTLFGEEARLERHRERKHNDGQFLCL 93
            ::.|.|..|...||.:.:...|  |......:.:.|..|..:|.:.:.|..||.....:..:.|.
Mouse   339 EKPYKCNECGKAFSVYSSLTTH--QAIHTGEKPYKCNECGKVFTQNSHLASHRGVHSGEKPYKCE 401

  Fly    94 QCGKKYASATFLYRHVASW--HGQQSLFYCDMCTDNCNDVKTFSGMLELQEHAEEVHR-LRTLKS 155
            :|||.::..:.|.||   |  |..:..:.|..|.      |.||....|..| :.:|. .:..|.
Mouse   402 ECGKLFSQTSNLARH---WRVHTGEKPYKCSECG------KAFSVRSSLIAH-QVIHTGEKPYKC 456

  Fly   156 T-ASDADSQVDEMEDLEMLEENIENILPSIDWDDDLTFGWPTDLDKESCIVNAKPSVFVCPFCAN 219
            | .....||...:.    :.:.|.                          ...||  :.|..|..
Mouse   457 TECGKVFSQTSSLS----IHQRIH--------------------------TGEKP--YRCNECGK 489

  Fly   220 GFPGSLSLVRHLEQVHE-RSALDCCYCGKSHGSREALRSHLQRVHILLRGHVCGICQADFATADH 283
            .|....:|..| :.:|. :....|..|||.......|.:| ||.|...:.:.|..|...|:....
Mouse   490 AFNSHSNLNTH-QVIHTGQKPYKCMQCGKVFTQNSHLANH-QRTHTGEKPYKCNECGKAFSVYSS 552

  Fly   284 LKKHVNSLHLDHRPHLCPTCGKRFTQRCHLTDHIKTDRGH------------------------- 323
            |..| .::|...:|:.|..|||.|||..||..|.:|..|.
Mouse   553 LTTH-QAIHTGEKPYKCNECGKVFTQNSHLASHRRTHTGEKPYQCNKCDKAFSVRSSLTTHQAIH 616

  Fly   324 -GHGTYTCEFCVRPFFRAIDL----ERHVCEEH 351
             |...|||..|.:.|.|:.:|    ..||.::|
Mouse   617 TGEKPYTCSECGKVFSRSSNLTSHQRLHVGQKH 649

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7101	NP_573329.2	PHA00733	<210..263	CDD:177301	14/53 (26%)
		C2H2 Zn finger	242..263	CDD:275368	8/20 (40%)
		C2H2 Zn finger	271..292	CDD:275368	5/20 (25%)
		C2H2 Zn finger	300..319	CDD:275368	10/18 (56%)
		C2H2 Zn finger	330..347	CDD:275368	5/20 (25%)
Zfp160	NP_663458.2	KRAB	8..68	CDD:214630
		KRAB	8..47	CDD:279668
		C2H2 Zn finger	148..168	CDD:275368
		C2H2 Zn finger	176..196	CDD:275368
		zf-H2C2_2	188..213	CDD:290200
		COG5048	200..635	CDD:227381	78/342 (23%)
		zf-C2H2	202..224	CDD:278523
		C2H2 Zn finger	204..224	CDD:275368
		zf-H2C2_2	216..240	CDD:290200
		C2H2 Zn finger	232..252	CDD:275368
		zf-H2C2_2	244..269	CDD:290200
		C2H2 Zn finger	260..280	CDD:275368
		zf-H2C2_2	272..297	CDD:290200
		C2H2 Zn finger	288..308	CDD:275368
		zf-H2C2_2	300..325	CDD:290200
		C2H2 Zn finger	316..336	CDD:275368
		C2H2 Zn finger	344..364	CDD:275368	6/21 (29%)
		zf-H2C2_2	356..381	CDD:290200	5/26 (19%)
		C2H2 Zn finger	372..392	CDD:275368	6/19 (32%)
		zf-H2C2_2	384..409	CDD:290200	7/24 (29%)
		C2H2 Zn finger	400..420	CDD:275368	8/22 (36%)
		zf-H2C2_2	412..436	CDD:290200	8/32 (25%)
		C2H2 Zn finger	428..448	CDD:275368	7/26 (27%)
		zf-H2C2_2	440..465	CDD:290200	5/25 (20%)
		C2H2 Zn finger	456..476	CDD:275368	3/23 (13%)
		zf-H2C2_2	468..493	CDD:290200	6/56 (11%)
		C2H2 Zn finger	484..504	CDD:275368	5/20 (25%)
		zf-H2C2_2	496..521	CDD:290200	7/25 (28%)
		C2H2 Zn finger	512..532	CDD:275368	8/20 (40%)
		zf-H2C2_2	524..548	CDD:290200	7/24 (29%)
		C2H2 Zn finger	540..560	CDD:275368	5/20 (25%)
		zf-H2C2_2	552..577	CDD:290200	9/25 (36%)
		C2H2 Zn finger	568..588	CDD:275368	10/19 (53%)
		zf-H2C2_2	580..604	CDD:290200	5/23 (22%)
		C2H2 Zn finger	596..616	CDD:275368	0/19 (0%)
		zf-H2C2_2	608..633	CDD:290200	6/24 (25%)
		C2H2 Zn finger	624..644	CDD:275368	5/19 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832280
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930