Protein Alignment CG42450 and Rgs19

DIOPT Version :10

• Sequence 1: NP_001259691.1
• Gene: CG42450 / 32874
• FlyBaseID: FBgn0259927
• Length: 1280
• Species: Drosophila melanogaster
• Sequence 2: NP_067693.1
• Gene: Rgs19 / 59293
• RGDID: 629471
• Length: 216
• Species: Rattus norvegicus
• Alignment Length: 198
• Identity: 61/198 - (30%)
• Similarity: 90/198 - (45%)
• Gaps: 34/198 - (17%)

  Fly   455 TFSEYDFFLQPALPSNP-----------------WVTEDIAFWQLNN----------TFVDIPTE 492
            :.|.:|     |.||.|                 |..|....||::.          .....|:.
  Rat    22 SMSSHD-----AAPSGPPSRNPCCLCWCCCCSCSWNQERQRAWQVSRESKLQPLPSCEVCTPPSP 81

  Fly   493 KRVKRWAISIEELVSDPTGLQEFTGFLEKEYSHENIRFWIAVNRLRRSAHSQVA-RKVNEIYEEF 556
            :.|:.||.|.::|:..|||...|..||..|||.||:.||:|...|:..|...|. .|...|||::
  Rat    82 EEVQSWAQSFDKLMHSPTGRSVFRAFLRTEYSEENMLFWLACEELKTEADRHVVDEKARLIYEDY 146

  Fly   557 LKPGAPCEINIDGKTMESVLKGLKNPSRFTFDSASEHIYMLLLKKDCYPRFIRSEHYKRLLDTGI 621
            :...:|.|:::|.:..|.:.:.::.||..|||.|...|| .|:.:|.||||:.|..|:.||..|.
  Rat   147 VSILSPKEVSLDSRVREGINRKMQEPSPHTFDDAQLQIY-TLMHRDSYPRFLTSPTYRSLLLQGA 210

  Fly   622 QPS 624
            ..|
  Rat   211 PQS 213

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42450	NP_001259691.1	DEP_RGS7-like	219..306	CDD:239897
		RGS_DHEX	303..401	CDD:375589
		G-gamma	418..482	CDD:459879	9/43 (21%)
		RGS_R7-like	494..614	CDD:188660	45/120 (38%)
Rgs19	NP_067693.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..30		3/12 (25%)
		RGS	87..204	CDD:470619	45/117 (38%)
		Interaction with GIPC	207..216		2/7 (29%)