Protein Alignment CG42450 and rgs6

DIOPT Version :10

• Sequence 1: NP_001259691.1
• Gene: CG42450 / 32874
• FlyBaseID: FBgn0259927
• Length: 1280
• Species: Drosophila melanogaster
• Sequence 2: NP_001030340.1
• Gene: rgs6 / 562667
• ZFINID: ZDB-GENE-030131-31
• Length: 489
• Species: Danio rerio
• Alignment Length: 492
• Identity: 191/492 - (38%)
• Similarity: 290/492 - (58%)
• Gaps: 51/492 - (10%)

  Fly   200 NQQQAIEKLSRP-------MAFDKMEMLVREMQDQEHGVPVRQQKMFLTSIPYAFMGYDLIEWLM 257
            :|.|....::.|       :|:.|:|.::..:||:..|||||..|.|||.||....|.|:::|:|
Zfish     5 SQDQGAVGIADPDEDSPNMIAYRKIEDIITRLQDEAEGVPVRTVKSFLTKIPNVVTGSDIVQWMM 69

  Fly   258 DRLQIEE-SEALNIANQLCLHGYFFPVNDSKTLTVKDDSSLYRFQTPYYWP---WQHKAPDNVEY 318
            ..|.:|: :||:::.:.:...||.||::| ..||:|||.:.||||.||:||   |:   |:|.:|
Zfish    70 KNLNMEDPAEAIHVGSLIAAQGYIFPISD-HVLTLKDDGTFYRFQAPYFWPSNCWE---PENTDY 130

  Fly   319 AIYLAKRSLRNKQRHALEDYEAEALASLHKNLKGKWDFISMQAEEQVRLAKERKKGDKIVGDSQE 383
            ||||.||:::||.|..|.|||||.||.|.:....||:||.||||.||::.:::.|.::.:.||||
Zfish   131 AIYLCKRTMQNKTRLELADYEAENLARLQRAFARKWEFIFMQAEAQVKIDRKKDKTERKILDSQE 195

  Fly   384 RAYWRVHRPPPGQFTPLE----PC---PVPSR----------DRQGLKP-------NKKKTVDDM 424
            ||:|.||||.||.....|    .|   ..|.|          |.|...|       :.|.|.:|:
Zfish   196 RAFWDVHRPVPGCVNTTEMDIRKCRRLKNPQRVKKSVYGVVDDTQTQSPVHTPAQQSSKDTKEDV 260

  Fly   425 QRDVDYLGKSLNRTRMKMSQACESLVCYSETFSEYDFFLQPALPSNPWVTEDIAFWQLNNTFVDI 489
            ::::.:|...|:|..||||:..|:|:.|:|.:.:||.|:....|||||:::|..||:|..:  ..
Zfish   261 EKEILFLNTQLDRHCMKMSKVAETLMSYTEQYLDYDPFVAVPEPSNPWISDDATFWELEAS--KD 323

  Fly   490 PTEKRVKRWAISIEELVSDPTGLQEFTGFLEKEYSHENIRFWIAVNRLRRSAHSQVARKVNEIYE 554
            |:::|||:|..|::|.:.||.|.::|..|||.|:|.||:.||:||..|:.....:||.:..||::
Zfish   324 PSQQRVKKWGFSLDEALKDPVGREQFLKFLESEFSSENLLFWLAVQDLKCRPLQEVASRAQEIWQ 388

  Fly   555 EFLKPGAPCEINIDGKTMESVLKGLKNPSRFTFDSASEHIYMLLLKKDCYPRFIRSEHYKRLL-- 617
            |||..|||..||:|..:.|...:.||:|.|::|:.|.:|||. |:|.|.||||:||..|:.||
Zfish   389 EFLAEGAPNAINLDSHSYERTSQNLKDPGRYSFEDAQDHIYK-LMKSDSYPRFLRSNAYQDLLLA 452

  Fly   618 ------DTGIQPSYKKRFFNFGGVSGAKKKMTAALSS 648
                  :.|.:.|.:| |....|.|...|::|..:.|
Zfish   453 RKKPETEQGRRTSLEK-FTRSVGKSLTSKRLTGLMQS 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42450	NP_001259691.1	DEP_RGS7-like	219..306	CDD:239897	37/87 (43%)
		RGS_DHEX	303..401	CDD:375589	50/100 (50%)
		G-gamma	418..482	CDD:459879	25/63 (40%)
		RGS_R7-like	494..614	CDD:188660	54/119 (45%)
rgs6	NP_001030340.1	DEP_RGS7-like	31..118	CDD:239897	37/87 (43%)
		RGS_DHEX	115..216	CDD:375589	51/103 (50%)
		GGL	257..318	CDD:128520	23/60 (38%)
		RGS_RGS6	327..451	CDD:188691	56/124 (45%)