Protein Alignment CG42450 and rgs3b

DIOPT Version :10

• Sequence 1: NP_001259691.1
• Gene: CG42450 / 32874
• FlyBaseID: FBgn0259927
• Length: 1280
• Species: Drosophila melanogaster
• Sequence 2: XP_068077654.2
• Gene: rgs3b / 557360
• ZFINID: ZDB-GENE-060531-24
• Length: 1156
• Species: Danio rerio
• Alignment Length: 620
• Identity: 128/620 - (20%)
• Similarity: 215/620 - (34%)
• Gaps: 180/620 - (29%)

  Fly    12 DRQLVLRNQSAALVPVVVSAPATGPGATTPNPQSSAQAQLSLVPSKPTSLSLQPHAVLQAMQQLS 76
            |:||.||.:             .||.... .|:::.||.|.|       |...||:|.:......
Zfish   689 DKQLALRER-------------IGPDQML-EPKAAEQADLGL-------LGFSPHSVSEPCSPSC 732

  Fly    77 PSAG---GNNNASSTAATATSSSSGNANSGSSPALASTATAISATTQAATAFSGSSVGHHHLQHH 138
            |||.   ...|.:|.|...:.....:||..|..:..:...:.:.|::.
Zfish   733 PSASPILRRTNCTSPAQRLSYPDLPDANQTSPTSRDACKPSYTDTSEI----------------- 780

  Fly   139 HQHTHPHAPQQSQSQQPQPQHQLQQPHPAGAPSSATQSHHHGSISVSGSGGGLLGSSGGSGNQQQ 203
                       .:::|.:.:....:....|...||::     :|||     |...:|..|.:...
Zfish   781 -----------WKNRQKEVKESDLEKREQGEGESASE-----TISV-----GARPTSSSSSSSPL 824

  Fly   204 AIEKLSRPMAFDKMEMLVREMQDQEHGVPVRQQKMFLTSIPYAFMGYDLIEWLMDRLQIEESEAL 268
            .|.||....:|:...:......|.:......::              |..|..:.|..:.||...
Zfish   825 VIPKLCLDRSFNTDALTSPSTDDDDDDEEEDEE--------------DSDEGFLKRRSMVESSPC 875

  Fly   269 --NIANQLCLHGYFFPVNDSKTLTVKDDSSLYRFQTPYYWPWQHKAPDNVEYAIYLAKRSLRNKQ 331
              ..:..||:                 ..||:|             ..:.|.::....||.|...
Zfish   876 GGQQSGGLCV-----------------QRSLHR-------------RTHSEGSLLQEPRSPRFIS 910

  Fly   332 RHALEDYEAEALASLHKNLKGKWDFISMQAEEQVRLAKERKKGDKIVGDSQERAYWRVHRPPPGQ 396
            ..|::..||:      :....:|...|.|.     |.||..|.    |.|       ||     |
Zfish   911 DQAIDCIEAK------RETPERWAVPSPQT-----LRKELTKN----GGS-------VH-----Q 948

  Fly   397 ----FTPLEPCPVPS----RDRQGLKPNKKKTV-DDMQRDVDYLGKSLNRTRMKMSQACESLVCY 452
                ||....|..|:    ..:..:|..|.|.: .||:..:.:|.|..|...            .
Zfish   949 ICLLFTGRRVCGKPNCKCDMGKTAVKKKKSKNLAKDMKNRLTFLRKKTNDRH------------G 1001

  Fly   453 SETFSEYDFFLQPALPSNPWVTEDIAFWQLNNTFVDIPTEKRVKRWAISIEELVSDPTGLQEFTG 517
            |...|:.|..|:.                      |.|..:...:||.|::.|:|...||..|..
Zfish  1002 SNPASKLDKVLKS----------------------DKPAPEEALKWAESLDTLLSHKYGLAVFRS 1044

  Fly   518 FLEKEYSHENIRFWIAVNRLRR-SAHSQVARKVNEIYEEFLKPGAPCEINIDGKTMESVLKGLKN 581
            ||:.|:|.||:.||:|....:: .:.|::..:..:|:.|::...:..|:|:|..|.|.:.:.::|
Zfish  1045 FLQTEFSEENLDFWLACEEFKKIKSLSKMTSRAKKIFTEYISIQSCKEVNLDSYTREHIKENMEN 1109

  Fly   582 PSRFTFDSASEHIYMLLLKKDCYPRFIRSEHYKRL 616
            .....||.|...|:. |:::|.||||:||:.|..|
Zfish  1110 ICADCFDLAQSRIFG-LMERDSYPRFLRSDIYMEL 1143

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42450	NP_001259691.1	DEP_RGS7-like	219..306	CDD:239897	11/88 (13%)
		RGS_DHEX	303..401	CDD:375589	21/101 (21%)
		G-gamma	418..482	CDD:459879	10/64 (16%)
		RGS_R7-like	494..614	CDD:188660	38/120 (32%)
rgs3b	XP_068077654.2	None