Protein Alignment CG42450 and Rgs6

DIOPT Version :10

• Sequence 1: NP_001259691.1
• Gene: CG42450 / 32874
• FlyBaseID: FBgn0259927
• Length: 1280
• Species: Drosophila melanogaster
• Sequence 2: XP_063118437.1
• Gene: Rgs6 / 54295
• RGDID: 3569
• Length: 591
• Species: Rattus norvegicus
• Alignment Length: 555
• Identity: 211/555 - (38%)
• Similarity: 314/555 - (56%)
• Gaps: 77/555 - (13%)

  Fly   197 GSGNQQQ---AIEKLSRP--MAFDKMEMLVREMQDQE-HGVPVRQQKMFLTSIPYAFMGYDLIEW 255
            |||:|:.   |..:.|.|  :.:.|:|.::.:|||.: .|||:|..|.||:.||....|.|:::|
  Rat    43 GSGDQRAVGVADPEESSPNMIVYCKIEDIITKMQDDKTGGVPIRTVKSFLSKIPSVVTGTDIVQW 107

  Fly   256 LMDRLQIEES-EALNIANQLCLHGYFFPVNDSKTLTVKDDSSLYRFQTPYYWP---WQHKAPDNV 316
            ||..|.||:. ||:::.:.:...||.||::| ..||:|||.:.||||.||:||   |:   |:|.
  Rat   108 LMKNLSIEDPVEAIHLGSLIAAQGYVFPISD-HVLTMKDDGTFYRFQAPYFWPSNCWE---PENT 168

  Fly   317 EYAIYLAKRSLRNKQRHALEDYEAEALASLHKNLKGKWDFISMQAEEQVRLAKERKKGDKIVGDS 381
            :|||||.||:::||.|..|.|||||.||.|.:....||:||.||||.||::.:::.|.::.:.||
  Rat   169 DYAIYLCKRTMQNKARLELADYEAENLARLQRAFARKWEFIFMQAEAQVKIDRKKDKTERKILDS 233

  Fly   382 QERAYWRVHRPPPGQFTPLE------------------------------PCPVPSRDRQGLKPN 416
            ||||:|.||||.||.....|                              |..:||      :|.
  Rat   234 QERAFWDVHRPVPGCVNTTEMDIRKCRRLKNPQKVKKSVYGVTDESQSQSPVHIPS------QPI 292

  Fly   417 KKKTVDDMQRDVDYLGKSLNRTRMKMSQACESLVCYSETFSEYDFFLQPALPSNPWVTEDIAFWQ 481
            :|.|.||:::.:.:|...::|..:|||:..|||:.|:|.:.|||.|:.||.|||||:::||..|.
  Rat   293 RKTTKDDIRKQITFLNAQIDRHCLKMSKVAESLIAYTEQYVEYDPFITPAEPSNPWISDDITLWD 357

  Fly   482 LNNTFVDIPTEKRVKRWAISIEELVSDPTGLQEFTGFLEKEYSHENIRFWIAVNRLRRSAHSQVA 546
            :..:  ..|:::|||||..|.:|::.|..|..:|..|||.|:|.||:|||:||..|::.....||
  Rat   358 IEMS--KEPSQQRVKRWGFSFDEILKDQVGRDQFLRFLESEFSSENLRFWLAVQDLKKQPLQDVA 420

  Fly   547 RKVNEIYEEFLKPGAPCEINIDGKTMESVLKGLKNPSRFTFDSASEHIYMLLLKKDCYPRFIRSE 611
            ::|.||::|||.||||..||:|..:.|...:.:|:..|:||:.|.||||. |:|.|.|.||:||.
  Rat   421 KRVEEIWQEFLAPGAPSAINLDSHSYEITSQNVKDGGRYTFEDAQEHIYK-LMKSDSYARFLRSN 484

  Fly   612 HYKRLL--------DTGIQPSYKKRFFNFGGVSGAKKKMTAALSSQ----PNLGDAAKGPSGTSA 664
            .|:.||        :.|.:.|.:|  |........:.:|.||...:    |.:|..|.|.:....
  Rat   485 AYQDLLLAKKKPESEQGRRTSLEK--FTRSVCCWRRLRMAAAFHPRGGFLPAVGKVAGGQAPYGP 547

  Fly   665 GSSMMQAPPPG-------NLARRR--GSDR-SLTG 689
            .:.::.||.||       :..|||  .:|| ||.|
  Rat   548 DAVLLTAPIPGSGPGPTEHPGRRRSTSNDRASLRG 582

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42450	NP_001259691.1	DEP_RGS7-like	219..306	CDD:239897	38/88 (43%)
		RGS_DHEX	303..401	CDD:375589	50/100 (50%)
		G-gamma	418..482	CDD:459879	28/63 (44%)
		RGS_R7-like	494..614	CDD:188660	56/119 (47%)
Rgs6	XP_063118437.1	None