Protein Alignment CG42450 and Rgs11

DIOPT Version :10

• Sequence 1: NP_001259691.1
• Gene: CG42450 / 32874
• FlyBaseID: FBgn0259927
• Length: 1280
• Species: Drosophila melanogaster
• Sequence 2: NP_062211.1
• Gene: Rgs11 / 54291
• RGDID: 3563
• Length: 467
• Species: Rattus norvegicus
• Alignment Length: 472
• Identity: 191/472 - (40%)
• Similarity: 282/472 - (59%)
• Gaps: 24/472 - (5%)

  Fly   207 KLSRPMAFDKMEMLVREMQDQEHGVPVRQQKMFLTSIPYAFMGYDLIEWLMDRLQIEESEALNIA 271
            ::.|| ...|||.:|..|||.:.||.:|.|::.:|.||:|..|.|::|||:.:..|.|.|||::.
  Rat    15 RMQRP-HLSKMERVVVSMQDPDQGVKMRSQRLLITVIPHAVAGRDIVEWLVQKFCISEEEALHLG 78

  Fly   272 NQLCLHGYFFPVNDSKTLTVKDDSSLYRFQTPYYWPWQHKAPDNVEYAIYLAKRSLRNKQRHALE 336
            ..|..|||.:|:.:|:.||::.|.:.|||||||:|.........::|||||||:::  :::.||.
  Rat    79 TLLTQHGYIYPLRESRDLTLRPDETPYRFQTPYFWTSTLWPAAELDYAIYLAKKNI--QKQGALV 141

  Fly   337 DYEAEALASLHKNLKGKWDFISMQAEEQVRLAKERKKGDKIVGDSQERAYWRVHRPPPGQFTPLE 401
            |||.|....|||.:...||.:.|||.||:|.||:|:|||::|...||:.||.|::||||....||
  Rat   142 DYEKEHYTLLHKKINHAWDLVLMQAREQLRAAKQRRKGDRLVISCQEQTYWLVNKPPPGAPNVLE 206

  Fly   402 PCPVPSRDRQGLKPNKKKTVDDMQR-DVDYLGKSLNRTRMKMSQACESLVCYSETFSEYDFFLQP 465
            ..|    :|....|::.:...|..: :::...|:|:|.|:|.|...|:.:.:|.....:|..|..
  Rat   207 QGP----ERGSDNPSQVQMSSDFYKCEIECFRKALSRNRVKSSVCLEAYLKFSSQHGPHDPILSG 267

  Fly   466 ALPSNPWVTEDIAFWQLNNTFVDIPTEKRVKRWAISIEELVSDPTGLQEFTGFLEKEYSHENIRF 530
            .||||||:|:|:.:|.:|...|..||:.||:||:.|..||:.||.|...|..||:||:|.||:.|
  Rat   268 CLPSNPWITDDVTYWVMNAPNVAAPTKLRVERWSFSFRELLDDPVGRIHFMDFLQKEFSAENLSF 332

  Fly   531 WIAVNRLRRSAHSQVARKVNEIYEEFLKPGAPCEINIDGKTMESVLKGLKNPSRFTFDSASEHIY 595
            |.|...||....:||...|:.:|::||.|||...||||.:|||..|:||:.|.|:..|:|..|||
  Rat   333 WEACEELRFGGQAQVPTLVDSVYQQFLAPGAARWINIDSRTMEWTLEGLRQPHRYVLDAAQLHIY 397

  Fly   596 MLLLKKDCYPRFIRSEHYKRLLDTGIQPSYKKRF-FNFGGVSGAKKKMTAALSSQPNLGDAAKGP 659
            | |:|||.||||::|:.|:.||:..:.|...||: |.|         :...|.|.|:  .|.:..
  Rat   398 M-LMKKDSYPRFLKSDIYRGLLEEAVIPLETKRWPFPF---------LRKPLHSSPS--PALQST 450

  Fly   660 SGTSAGSSMMQAPPPGN 676
            ||..|.:|   :|..||
  Rat   451 SGEPAATS---SPAGGN 464

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42450	NP_001259691.1	DEP_RGS7-like	219..306	CDD:239897	38/86 (44%)
		RGS_DHEX	303..401	CDD:375589	43/97 (44%)
		G-gamma	418..482	CDD:459879	20/64 (31%)
		RGS_R7-like	494..614	CDD:188660	59/119 (50%)
Rgs11	NP_062211.1	DEP_RGS7-like	26..113	CDD:239897	38/86 (44%)
		RGS_DHEX	110..209	CDD:375589	45/100 (45%)
		GGL	224..284	CDD:128520	20/59 (34%)
		RGS	295..420	CDD:470619	62/125 (50%)