Protein Alignment CG42450 and rgs7a

DIOPT Version :10

• Sequence 1: NP_001259691.1
• Gene: CG42450 / 32874
• FlyBaseID: FBgn0259927
• Length: 1280
• Species: Drosophila melanogaster
• Sequence 2: XP_021322816.2
• Gene: rgs7a / 436814
• ZFINID: ZDB-GENE-040718-276
• Length: 487
• Species: Danio rerio
• Alignment Length: 491
• Identity: 192/491 - (39%)
• Similarity: 286/491 - (58%)
• Gaps: 59/491 - (12%)

  Fly   212 MAFDKMEMLVREMQDQEHGVPVRQQKMFLTSIPYAFMGYDLIEWLMDRLQIEES-EALNIANQLC 275
            :.:.|||.::..|||:::|:|:|..|.||:.||..|.|.|:::||:..|.||:. |||::...:.
Zfish    22 LVYRKMEDVIARMQDEKNGIPIRTVKSFLSKIPSVFSGSDIVQWLLKNLCIEDQVEALHLGTLMA 86

  Fly   276 LHGYFFPVNDSKTLTVKDDSSLYRFQTPYYWP---WQHKAPDNVEYAIYLAKRSLRNKQRHALED 337
            .||||||::| ..||:|||.:.|||||||:||   |:   |:|.:||:||.||:::||.|..|.|
Zfish    87 AHGYFFPISD-HVLTLKDDGTFYRFQTPYFWPSNCWE---PENTDYAVYLCKRTMQNKARLELAD 147

  Fly   338 YEAEALASLHKNLKGKWDFISMQAEEQVRLAKERKKGDKIVGDSQERAYWRVHRPPPGQFTPLE- 401
            ||||:||.|.:....||:||.||||.|.::.|:|.|.::.:.||||||:|.||||.||.....|
Zfish   148 YEAESLARLQRAFARKWEFIFMQAEAQAKVDKKRDKIERKILDSQERAFWDVHRPVPGCVNTTEV 212

  Fly   402 ------PCPVPSRDRQ---GLKPN--------------KKKTVDDMQRDVDYLGKSLNRTRMKMS 443
                  ....|.:.|:   ||:.:              |:.|.:::|..:.:....|:|.|:|||
Zfish   213 DIKKSSRMKNPHKTRKSVYGLQNDIRSHSPTHTPAPEAKQPTEEELQEQIKFWQAQLDRHRLKMS 277

  Fly   444 QACESLVCYSETFSEYDFFLQPALPSNPWVTEDIAFWQLNNTFVDIPTEKRVKRWAISIEELVSD 508
            :..|||:.|:|.:|:||.||....|||||:::|...|::..:  ..|.:.||:||...|:|::.|
Zfish   278 KVAESLLSYAEQYSDYDPFLSTPDPSNPWMSDDTTLWEMEAS--KEPGQTRVRRWGFGIDEVLKD 340

  Fly   509 PTGLQEFTGFLEKEYSHENIRFWIAVNRLRRSAHSQVARKVNEIYEEFLKPGAPCEINIDGKTME 573
            |.|.::|..|||.|:|.||:|||:||..|:|....:|..:|.||:||||..|||..||:|.|:.:
Zfish   341 PVGREQFLKFLESEFSSENLRFWLAVQELKRRPIREVPTRVQEIWEEFLAAGAPSAINVDSKSYD 405

  Fly   574 SVLKGLKNPSRFTFDSASEHIYMLLLKKDCYPRFIRSEHYKRLLDTGIQPSYKKRFFNFGGVSGA 638
            ...:.:|:|.|:.|:.|.||||. |:|.|.|.|||||..|:.||.                   |
Zfish   406 KTTQNVKDPGRYAFEDAQEHIYK-LMKSDSYSRFIRSSAYQELLQ-------------------A 450

  Fly   639 KKKMTAALSSQPNLGDAAKGPSGTSAGSSMMQAPPP 674
            |||..:....:.:.....:     :.|.|::...||
Zfish   451 KKKSGSIQDRRTSFEKFTR-----NVGKSLISKRPP 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42450	NP_001259691.1	DEP_RGS7-like	219..306	CDD:239897	41/87 (47%)
		RGS_DHEX	303..401	CDD:375589	50/100 (50%)
		G-gamma	418..482	CDD:459879	25/63 (40%)
		RGS_R7-like	494..614	CDD:188660	57/119 (48%)
rgs7a	XP_021322816.2	None