Protein Alignment CG42450 and Rgs9

DIOPT Version :10

• Sequence 1: NP_001259691.1
• Gene: CG42450 / 32874
• FlyBaseID: FBgn0259927
• Length: 1280
• Species: Drosophila melanogaster
• Sequence 2: NP_062097.1
• Gene: Rgs9 / 29481
• RGDID: 3572
• Length: 677
• Species: Rattus norvegicus
• Alignment Length: 794
• Identity: 250/794 - (31%)
• Similarity: 375/794 - (47%)
• Gaps: 181/794 - (22%)

  Fly   210 RP-MAF-DKMEMLVREMQDQEHGVPVRQQKMFLTSIPYAFMGYDLIEWLMDRLQIEESEALNIAN 272
            || ||| .|:|.||::||:.|.||.::.|::.:||:|:|..|.|:::|::.||.|...||.|:.|
  Rat    11 RPRMAFLQKIEALVKDMQNPETGVRMQNQRVLVTSVPHAMTGGDVLQWIIQRLWISNLEAQNLGN 75

  Fly   273 QLCLHGYFFPVNDSKTLTVKDDSSLYRFQTPYYWPWQHKAPDNVEYAIYLAKRSLRNKQRHALED 337
            .:..:||.:|:.|.|.|.:|.|||||||||||:||.|....::.:||||||||::  |::..||:
  Rat    76 FIVKYGYIYPLQDPKNLVLKPDSSLYRFQTPYFWPTQQWPAEDTDYAIYLAKRNI--KKKGILEE 138

  Fly   338 YEAEALASLHKNLKGKWDFISMQAEEQVRLAKERKKGDKIVGDSQERAYWRVHRPPPGQFTPLEP 402
            ||.|....|:|.:..||||:.|||:||.|..|||.|.|:...|.||:|||.|||.|||....|:
  Rat   139 YEKENYDFLNKKINYKWDFVIMQAKEQYRTGKERNKADRYALDCQEKAYWLVHRSPPGMNNVLD- 202

  Fly   403 CPVPSRDRQGL----KPN--KKKTVDDMQRDVDYLGKSLNRTRMKMSQACESLVCYSETFSEYDF 461
                    .||    .||  ||:||..:::::.|..::|.|:.:|.|.:...:|.|||.||..|.
  Rat   203 --------YGLDRVTNPNEVKKQTVTAVRKEIMYYQQALMRSTVKSSVSLGGIVKYSEQFSSNDA 259

  Fly   462 FLQPALPSNPWVTEDIAFWQLNNTFVDIPTEKRVKRWAISIEELVSDPTGLQEFTGFLEKEYSHE 526
            .:...||||||:|:|..||.||...|::||:.||:|||.:..||:.||.|.|.|..||:||:|.|
  Rat   260 IMSGCLPSNPWITDDTQFWDLNAKLVEVPTKMRVERWAFNFSELIRDPKGRQSFQYFLKKEFSGE 324

  Fly   527 NIRFWIAVNRLRRSAHSQVARKVNEIYEEFLKPGAPCEINIDGKTMESVLKGLKNPSRFTFDSAS 591
            |:.||.|...|:....|:|..|..|||:.||.|||...||||||||:..:|||::|.|:..|:|.
  Rat   325 NLGFWEACEDLKYGDQSKVKEKAEEIYKLFLAPGARRWINIDGKTMDITVKGLRHPHRYVLDAAQ 389

  Fly   592 EHIYMLLLKKDCYPRFIRSEHYKRLLDTGIQPSYKKRFFNFGGVSGAKKKMTAALSSQPNLGDAA 656
            .|||| |:|||.|.|:::|..||.:|...|:|                ::.|...|:.|.:
  Rat   390 THIYM-LMKKDSYARYLKSPIYKEMLAKAIEP----------------QETTKRSSTLPFM---- 433

  Fly   657 KGPSGTSAGSSMMQAPPPGNLARRRGSDRSLTGSAHELAVIGVNKDAGSKVPHSHSQSNLSEIPF 721
                    ...:..:|.|..|.:....:|:              ::|.:.|..:....:|:
  Rat   434 --------RRHLRSSPSPVILRQLEEEERA--------------REAANTVDITQPGQHLA---- 472

  Fly   722 SSDSIYRGDMPQRHMAIMDIGIYAAYGNRESSLQALPETPKTKTTVLDATESTSSSTALAAAASS 786
                      |..|:|     :|..        ..:|.:|               |:..:.:..|
  Rat   473 ----------PSPHLA-----VYTG--------TCVPPSP---------------SSPFSPSCRS 499

  Fly   787 AVCPWDDPAESVPPPPPPAQVKLSVCPWELDSATETPTAAPAVGSGG--GGAGASKILSSTGQPM 849
            ...|:..|:..:..|      .:::||        :|......||.|  |...||...::.|.|:
  Rat   500 PRKPFPSPSRFIRRP------SIAICP--------SPIRVALEGSSGLEGKGEASWSGANPGPPV 550

  Fly   850 RLN-STSSDNS--------DVNDRMQRNLG----------------------IRHQNTVDSGEAG 883
            ..: .||.|.|        .:..|...:||                      :.|......|:.|
  Rat   551 TESIETSVDRSRPHSQPRAPLKARAALSLGRFLRRGCLASPVFARLSPKCPSVSHGKVQPLGDMG 615

  Fly   884 IKRLIPNIPEQRRASVSFTPSPTPDFQLGRTPTTTSSPTVAPSSSTPLQARSAVYGSGQGIAKDP 948
              :.:|.:..::.|:.         ||:.....|.|.|.:..|.                   ||
  Rat   616 --QQLPRLKPKKVANF---------FQIKMEMPTDSGPCLMDSD-------------------DP 650

  Fly   949 PSGSDVDAELEEEL 962
            .:|...|...|:|:
  Rat   651 GAGESGDQTTEKEV 664

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42450	NP_001259691.1	DEP_RGS7-like	219..306	CDD:239897	40/86 (47%)
		RGS_DHEX	303..401	CDD:375589	48/97 (49%)
		G-gamma	418..482	CDD:459879	25/63 (40%)
		RGS_R7-like	494..614	CDD:188660	60/119 (50%)
Rgs9	NP_062097.1	DEP_RGS7-like	22..109	CDD:239897	40/86 (47%)
		RGS_DHEX	106..205	CDD:375589	49/109 (45%)
		GGL	219..280	CDD:128520	23/60 (38%)
		RGS_RGS9	292..412	CDD:188693	61/120 (51%)
		PHA03379	<502..>568	CDD:223066	18/79 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	530..571		11/40 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	639..677		9/45 (20%)