Protein Alignment CG42450 and rgs-3

DIOPT Version :10

• Sequence 1: NP_001259691.1
• Gene: CG42450 / 32874
• FlyBaseID: FBgn0259927
• Length: 1280
• Species: Drosophila melanogaster
• Sequence 2: NP_495223.1
• Gene: rgs-3 / 174020
• WormBaseID: WBGene00004346
• Length: 363
• Species: Caenorhabditis elegans
• Alignment Length: 386
• Identity: 85/386 - (22%)
• Similarity: 140/386 - (36%)
• Gaps: 97/386 - (25%)

  Fly   262 IEESEALNIANQLCLHGYFFPV-NDSKTLTVKDDSSLY-------------RFQTPYYWPWQHKA 312
            |..|.:...:|.:.|.   .|: |.|.|.......|:|             |.|.|.      ..
 Worm    41 ITSSTSAPASNDVTLQ---VPITNSSATSPTPSTGSMYFIAGMFDGKEKVNREQPPM------PT 96

  Fly   313 PDNVEYAIYLAKRSLRNKQRHALEDYEAEALASLHKNLKGKWDF----ISMQAEEQVRLAKERKK 373
            .|.|||            .|.|  .:.|...|::..:.|||..|    ....|||.:...:..:|
 Worm    97 TDGVEY------------PRAA--SWAAGNCANVLNDDKGKQLFRVFLFQSLAEENLAFLEAMEK 147

  Fly   374 GDKIVGDSQERAYWRVHRPPPGQFTPLEPCPVPSRDRQGLKPNKKKTVDDMQRDVDYLGKSLNRT 438
            ..|:....::.||                              .|:.::..|..::....|:...
 Worm   148 LKKMKISDEKVAY------------------------------AKEILETYQGSINLSSSSMKSL 182

  Fly   439 RMKMSQACESLVCYSETFSEYDFFLQPALPSNPWVTEDIAF--WQLNNTFVDIPTE----KRVKR 497
            |..::         |||....:|  .||:.....:.|:..|  ::.:..:::...|    ...::
 Worm   183 RNAVA---------SETLDMEEF--APAIKEVRRLLENDQFPRFRRSELYLEYLEELLPRSYAEK 236

  Fly   498 WAISIEELVSDPTGLQEFTGFLEKEYSHENIRFWIAVNRLRRSAHSQVARKVNE----IYEEFLK 558
            ||.|.|.|:.:..|...|..||...::.||:|||.||...|.|.|.  |..:|.    |...:|.
 Worm   237 WAQSFEGLLGNHVGRHHFRIFLRSIHAEENLRFWEAVVEFRSSRHK--ANAMNNLGKVILSTYLA 299

  Fly   559 PGAPCEINIDGKTMESVLKGLK-NPSRFT-FDSASEHIYMLLLKKDCYPRFIRSEHYKRLL 617
            .|...|:.:.....:.:.:.:: |....| ||.|.:|:.. :|:.|.|.||::|..|..||
 Worm   300 EGTTNEVFLPFGVRQVIERRIQDNQIDITLFDEAIKHVEQ-VLRNDPYVRFLQSSQYIDLL 359

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42450	NP_001259691.1	DEP_RGS7-like	219..306	CDD:239897	13/57 (23%)
		RGS_DHEX	303..401	CDD:375589	20/101 (20%)
		G-gamma	418..482	CDD:459879	12/65 (18%)
		RGS_R7-like	494..614	CDD:188660	37/125 (30%)
rgs-3	NP_495223.1	RGS	112..218	CDD:214613	24/146 (16%)
		RGS	240..358	CDD:459870	36/120 (30%)