Protein Alignment CG42450 and LOC1277215

DIOPT Version :10

• Sequence 1: NP_001259691.1
• Gene: CG42450 / 32874
• FlyBaseID: FBgn0259927
• Length: 1280
• Species: Drosophila melanogaster
• Sequence 2: XP_061506974.1
• Gene: LOC1277215 / 1277215
• VectorBaseID: AGAMI1_010659
• Length: 581
• Species: Anopheles gambiae
• Alignment Length: 686
• Identity: 230/686 - (33%)
• Similarity: 334/686 - (48%)
• Gaps: 161/686 - (23%)

  Fly    10 DRDRQLVLRNQSAALVPVVVSAP----ATGPGATTPNPQSSAQAQLSLVPSKPTSLSLQPHAVLQ 70
            |:|:         |.|.||:|||    |.|      |.:...:.:.::.
Mosquito     9 DKDK---------AAVTVVISAPKKMNANG------NEKDKDRDRETIT---------------- 42

  Fly    71 AMQQLSPSAGGNNNASSTAA-------TATSSSSGNA------------NSGSSPALASTATAIS 116
                   |:..:||.:..:|       |.|...:|||            :|.||..:|:|:||..
Mosquito    43 -------SSNSSNNCNRGSAGTDGGEGTVTQGGAGNAVVPPAGSGGSNISSSSSTTVATTSTATI 100

  Fly   117 ATTQAATAFSGSSVGHHHLQHHHQHTHPHAPQQSQSQQPQPQHQLQQPHPAGAPSSATQSHHHGS 181
            .||..||..|.::.|
Mosquito   101 TTTTTATISSSAAAG-------------------------------------------------- 115

  Fly   182 ISVSGSGGGLLGSSGGSGNQQ--QAIEKLSRP--MAFDKMEMLVREMQDQEHGVPVRQQKMFLTS 242
             :.:||.|...|..|...:.|  ||......|  :.:.|||.:|..||.:|.||.||..|.|::.
Mosquito   116 -TSAGSSGNKPGQGGQPSHAQATQAALNQDAPNILVYKKMEAIVERMQGEEGGVSVRTIKAFMSK 179

  Fly   243 IPYAFMGYDLIEWLMDRLQIEE-SEALNIANQLCLHGYFFPVNDSKTLTVKDDSSLYRFQTPYYW 306
            :|..|.|.|||.|:|..|.|:: :|||::|:.|..|||.||::|.: ||||:|.:.|||||||:|
Mosquito   180 VPSVFTGADLIAWIMKNLSIDDVNEALHLAHLLASHGYLFPIDDHQ-LTVKNDGTFYRFQTPYFW 243

  Fly   307 P---WQHKAPDNVEYAIYLAKRSLRNKQRHALEDYEAEALASLHKNLKGKWDFISMQAEEQVRLA 368
            |   |:   |:|.:||:||.||:::||.|..|.|||||.||.|.|....||:||.||||.|.::.
Mosquito   244 PSNCWE---PENTDYAVYLCKRTMQNKTRLELADYEAENLAKLQKMFSRKWEFIFMQAEAQSKVD 305

  Fly   369 KERKKGDKIVGDSQERAYWRVHRPPPGQFTPLEPCPVPSRDRQGLK---------PNKKKTVDDM 424
            |:|.|.::.|.||||||:|.||||.||.....| ..:....|:|..         ......|:.:
Mosquito   306 KKRDKLERKVLDSQERAFWDVHRPMPGCVNTTE-VDIKKAYRRGASSLGSGSSGTAGNSNPVEQL 369

  Fly   425 QRDVDYLGKSLNRTRMKMSQACESLVCYSETFSEYDFFLQPALPSNPWVTEDIAFWQLNNTFVDI 489
            .|.:..|...|.|..:|:|:..||...|.|.::|||.||.|....|||:|::...|..:.|..|:
Mosquito   370 TRQIKLLKLKLERRTIKISKVAESYTSYFEQYNEYDSFLNPPDQPNPWITDNTEMWDADRTAKDV 434

  Fly   490 PTEKRVKRWAISIEELVSDPTGLQEFTGFLEKEYSHENIRFWIAVNRLRRSAHSQVARKVNEIYE 554
             :.||||||..|:.||::||.|.::|:.||:||:|.||::||.:|..::....|:|....:.||.
Mosquito   435 -SLKRVKRWGFSLRELLNDPVGREQFSKFLDKEFSGENLKFWESVQSMKAQPQSKVKEAAHAIYL 498

  Fly   555 EFLKPGAPCEINIDGKTMESVLKGLKN---PSRFTFDSASEHIYMLLLKKDCYPRFIRSEHYKRL 616
            |||.|.|||.:|:|.|:||...:.:.:   |:|:.||.|:.|:|. |:|.|.|.|::||:.||..
Mosquito   499 EFLAPDAPCPVNVDSKSMELAREAVSSAAPPNRWCFDVAAAHVYH-LMKSDSYSRYLRSDMYKEY 562

  Fly   617 LDTGIQPSYKKRFFNFGGVSGAKKKMTAALSSQPNL 652
            |                  :|:|||    :.|.|||
Mosquito   563 L------------------NGSKKK----IKSIPNL 576

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42450	NP_001259691.1	DEP_RGS7-like	219..306	CDD:239897	43/87 (49%)
		RGS_DHEX	303..401	CDD:375589	52/100 (52%)
		G-gamma	418..482	CDD:459879	22/63 (35%)
		RGS_R7-like	494..614	CDD:188660	52/122 (43%)
LOC1277215	XP_061506974.1	None