Protein Alignment CG42450 and fhip1a

DIOPT Version :10

• Sequence 1: NP_001259691.1
• Gene: CG42450 / 32874
• FlyBaseID: FBgn0259927
• Length: 1280
• Species: Drosophila melanogaster
• Sequence 2: XP_002933543.3
• Gene: fhip1a / 100486834
• XenbaseID: XB-GENE-951017
• Length: 981
• Species: Xenopus tropicalis
• Alignment Length: 956
• Identity: 173/956 - (18%)
• Similarity: 282/956 - (29%)
• Gaps: 380/956 - (39%)

  Fly   218 EMLVREM-QDQEHGVPVRQQKMFLTSIPYAFMGYDLIEWLMDRLQIEESEALNIANQLCLHGYFF 281
            |:||.:. |...|..|:.:..|.|.|   |..|        ....:.|::...:.||||
 Frog   122 ELLVTQSHQPLLHHKPILKPLMMLLS---ACSG--------TSTAVVETKLAVLLNQLC------ 169

  Fly   282 PVNDSKTLTVKDDSSLYRFQTPYYWPWQHKAPDNVEYAIYLAKRSLRNKQRHALEDYEA-EALAS 345
                  ::..||.|.|..|        .|.:.|.......:....:....|......:| :||..
 Frog   170 ------SILAKDPSILELF--------FHTSEDQGAANFLIFSLLIPFIHREGTVGQQARDALLF 220

  Fly   346 LHKNLKGKWDFISMQAEEQVRLAKERKKGDKIVGDSQERAYWRVHRPPPGQFTPLEPCPVPSRDR 410
            :          :|:.||..| :||...:|...                         |||.:...
 Frog   221 I----------MSLSAENNV-VAKHIVEGTFF-------------------------CPVLATGL 249

  Fly   411 QGLKPNKKKTVDDMQRDVDYLGKSLNRTRMKMSQAC---ESLVCYSETFSEYDFFLQPALPSNPW 472
            .||..:....:||...|...|          :.:.|   ..|:.:..:....:..:|.|   :|.
 Frog   250 SGLYSSLPTKLDDKGEDWHCL----------LKEDCLQIPELIQFQNSLEFCNAVIQVA---HPL 301

  Fly   473 VTEDIAFWQLNNTFVDIPTEKRVKRWAISIEEL-------------VSDPTGLQEFTGFLEKEYS 524
            :...:..:..|...:.:......|   :::||:             ||:||.|:.|..|: ..:.
 Frog   302 IRAQLVDYIFNGFLLPVVAPALHK---VTVEEVMTTTAYLDLFLRSVSEPTLLKIFLRFI-LIHQ 362

  Fly   525 HENI-----------------------------------------RFWIAVNRLRRSAHSQVARK 548
            ||.:                                         |:.|..|.:..:..|.|  :
 Frog   363 HEKVHILDTLVSRINTPFRLCVVSLALFRTLIGLHCEDVMLQLILRYLIPCNHVMVTQRSAV--R 425

  Fly   549 VNEIY----EEFLKPGAPC---EINIDG-----KTMESVLKGLKNPSRFTFDSASEHIYMLLLKK 601
            ..:.|    |:||.....|   .::..|     :||.|..:      :.|....|:|:|    :|
 Frog   426 EQDCYSACAEKFLSLTPECCALTVSSTGYLERRQTMYSKFR------QRTDSDDSKHLY----EK 480

  Fly   602 DCYPRFIRSEHYKRLLDTGIQPSYKKRFFNFGGVSGAKKKMTAALSSQPNLGDAAKGPSGTSAGS 666
            |            .|:|                                  ||.|:
 Frog   481 D------------TLMD----------------------------------GDCAE--------- 490

  Fly   667 SMMQAPPPGNLARRRGSDRSLTGSAHELAVIGVNKDAGSKV---PHSHSQSNLSEIPFSS---DS 725
                 |...|..       .....||| .::...:|.  ||   |:. .|:...||...:   |:
 Frog   491 -----PVDDNYL-------EYLWEAHE-NILNCLEDC--KVWSAPYD-GQNPDPEISLKALMEDN 539

  Fly   726 IYRGDMP-----QRHMAIMDIGIYAAYGNRESSLQALPETPKT-KTTVLDATESTSSSTALAAAA 784
            ..||:.|     .||           |.:..||     |||.. ..|:||.....|..|.::..:
 Frog   540 CRRGEFPTFRRATRH-----------YMDSFSS-----ETPSLGGKTLLDLEWDDSYDTGMSPDS 588

  Fly   785 SSAVCPWDDPAESVPPPPPPAQVKLSVCPWELDSATETPTAAPAVGSGGGGAGASKILSSTGQP- 848
            .|  |......::|.||.||..::            |....|.....|      |.|..|..|.
 Frog   589 GS--CSPQPSIDAVLPPEPPHHIQ------------EMKRNAIMFIKG------SYIEESDFQDD 633

  Fly   849 ---MRL------------NSTSSDNSDVNDRM---------QRNLGIRHQNTVDSGEAGIKRLIP 889
               .||            |.|..::.:.||:.         |.|.........|:.:..:|:.:|
 Frog   634 VMVYRLCAVKDAKDADMQNITDKNDIETNDQFTKPQEGNQTQANYNKNANLNEDTVKTQVKQTLP 698

  Fly   890 NIPEQRRASVSFTPSPTPDFQLGRTPTTTSSPTVAPSSSTPLQARSAVYGSGQGIAKDPPSGSDV 954
            .:..|.        ||..|       ..::..|::|.|                        .:.
 Frog   699 KVKIQL--------SPAAD-------DISNMNTLSPDS------------------------EEF 724

  Fly   955 DAELEEELN--KISLGESSISEPPLLVVPTPEQTPPPITKITPPPGESENQADQVIDSTEIPGSS 1017
            .|..::.||  |.|..|..||               ||..:..|..|.|::.|:.  |.::|  .
 Frog   725 IARYDDMLNGLKTSTLEDVIS---------------PIHSLASPMEEDEDEFDKY--SLDLP--Q 770

  Fly  1018 CSTQANQFGEATATVTTVKEVQIELIEQVSGVQTEPDSPPTIKVLV 1063
            ..:..:.||...||:.:         ..:...||.|.:.|.|.|::
 Frog   771 AESIPSPFGPRDATIFS---------NFLPRPQTAPFTGPFISVVL 807

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42450	NP_001259691.1	DEP_RGS7-like	219..306	CDD:239897	20/87 (23%)
		RGS_DHEX	303..401	CDD:375589	13/98 (13%)
		G-gamma	418..482	CDD:459879	9/66 (14%)
		RGS_R7-like	494..614	CDD:188660	32/185 (17%)
fhip1a	XP_002933543.3	RAI16-like	87..410	CDD:370927	62/371 (17%)
		DUF5917	799..892	CDD:466037	3/9 (33%)
		KELAA	950..976	CDD:466035