DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Atg101 and atg101

DIOPT Version :9

Sequence 1:	NP_573326.1	Gene:	Atg101 / 32871	FlyBaseID:	FBgn0030960	Length:	218	Species:	Drosophila melanogaster
Sequence 2:	NP_001032316.1	Gene:	atg101 / 567680	ZFINID:	ZDB-GENE-051030-36	Length:	218	Species:	Danio rerio

Alignment Length:	218	Identity:	115/218 - (52%)
Similarity:	160/218 - (73%)	Gaps:	0/218 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MNARSQVFDLTMEGRQVDEAVATIFHTVLFHRCLGKYMYTGDAQYSIGTVGYTDVDCNFIDFTYV 65
            ||.||:|.::::||||||||:..:.||:|.||..||:.|..:..|||||||..||||:|||||:|
Zfish     1 MNCRSEVLEVSVEGRQVDEAMLGLLHTILLHRSTGKFHYKKEGTYSIGTVGTQDVDCDFIDFTFV 65

  Fly    66 CCTSDSLTHKVKRAINSFSEKLRSNESCGSGQISLEFFQKKKNRWPFPQESIPWEVWTVHLDLIK 130
            ..:||.|...:::|:..|.:.|.::.|.|.|||||||:||||:||||..|.||||||::.::::.
Zfish    66 RVSSDELDRVIRKAVAEFKDALGNSGSDGMGQISLEFYQKKKSRWPFSDECIPWEVWSIKVNVVN 130

  Fly   131 HENEDERQLCRENVSDLLTEKVIYITELMNRHDYVPKTPSQSELDLIFDTSFPDVQPYLFKFDYS 195
            ..||.|||:|||.|.:.|.||||.|.|::|||:|:||.|:|||:|.:||||..||||||:|..|.
Zfish   131 LANEQERQICREKVGEKLGEKVINIVEVINRHEYLPKMPTQSEVDNVFDTSLKDVQPYLYKITYQ 195

  Fly   196 TSGSAAPSMGNAMKKIIKETLAM 218
            .:.|...|:...|:::||:|||:
Zfish   196 ITDSLGTSVSTTMRRLIKDTLAL 218

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Atg101	NP_573326.1	ATG101	9..172	CDD:400281	86/162 (53%)
atg101	NP_001032316.1	DUF1649	9..172	CDD:285139	86/162 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580387
Domainoid	1	1.000	194	1.000	Domainoid score	I3133
eggNOG	1	0.900	-	-		E1_KOG4493
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11072
Inparanoid	1	1.050	252	1.000	Inparanoid score	I3207
OMA	1	1.010	-	-		QHG48336
OrthoDB	1	1.010	-	-		D1539728at2759
OrthoFinder	1	1.000	-	-		FOG0005798
OrthoInspector	1	1.000	-	-		oto39885
orthoMCL	1	0.900	-	-		OOG6_104431
Panther	1	1.100	-	-	LDO	PTHR13292
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R775
SonicParanoid	1	1.000	-	-		X5518
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800