DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Atg101 and epg-9

DIOPT Version :9

Sequence 1:	NP_573326.1	Gene:	Atg101 / 32871	FlyBaseID:	FBgn0030960	Length:	218	Species:	Drosophila melanogaster
Sequence 2:	NP_741338.2	Gene:	epg-9 / 177040	WormBaseID:	WBGene00022078	Length:	260	Species:	Caenorhabditis elegans

Alignment Length:	257	Identity:	84/257 - (32%)
Similarity:	119/257 - (46%)	Gaps:	50/257 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MNARSQVFDLTMEGRQVDEAVATIFHTVLFHRCLGKYMYTGDAQYSIGTVGYTDVDCNFIDFTYV 65
            ||.|.....||:|.|||.:||..|||::|.||.||::.|..:..:|:|::|..:|.|..||.|||
Worm     1 MNIRQNELRLTVELRQVTDAVECIFHSLLLHRTLGRFQYNDEKTFSMGSIGIKEVSCEQIDMTYV 65

  Fly    66 CCTSDSLTHKVKRAINSFSEKLRSNESCG--------------------SGQISLEFFQKKKN-- 108
            ...|..|...|...|..|..::......|                    |.||.|:|:.|.|.
Worm    66 RVNSTELAMCVDEDIRQFKCEVEEATCSGSIPRRTPTVGSPTDSAIPLLSAQIGLQFYTKSKKPN 130

  Fly   109 -------RW-----------PFPQESIPWEVWTVHLDLIKHENEDERQLCRENVSDLLTEKVIYI 155
                   .|           ....:...||.|.:.||:.:.|:.||.|..|:.|:|.:.|||:.|
Worm   131 SVIGTAVTWFGGAAATATGATVADDGTSWEEWKLILDVFRVESIDELQKMRQRVADDIGEKVLDI 195

  Fly   156 TELMNRHDYVPKTPSQSELDLIFDTSFPDVQPYLFKFDYSTSGSAAPSMGNAMKKIIKETLA 217
            .|.:|.:.|.||.|:::|:..||:|.|.|.||||||.    ...|.|.|.:      |::||
Worm   196 CEHINHNHYTPKMPTKTEIPEIFETKFSDCQPYLFKI----RRQAVPQMEH------KQSLA 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Atg101	NP_573326.1	ATG101	9..172	CDD:400281	63/202 (31%)
epg-9	NP_741338.2	DUF1649	10..212	CDD:285139	63/201 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159139
Domainoid	1	1.000	97	1.000	Domainoid score	I4590
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11072
Inparanoid	1	1.050	126	1.000	Inparanoid score	I3273
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48336
OrthoDB	1	1.010	-	-		D1539728at2759
OrthoFinder	1	1.000	-	-		FOG0005798
OrthoInspector	1	1.000	-	-		oto17769
orthoMCL	1	0.900	-	-		OOG6_104431
Panther	1	1.100	-	-	LDO	PTHR13292
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R775
SonicParanoid	1	1.000	-	-		X5518
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	14	13.940