DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG6961 and Alyref

DIOPT Version :9

Sequence 1:NP_573325.1 Gene:CG6961 / 32869 FlyBaseID:FBgn0030959 Length:474 Species:Drosophila melanogaster
Sequence 2:NP_035698.1 Gene:Alyref / 21681 MGIID:1341044 Length:255 Species:Mus musculus


Alignment Length:200 Identity:56/200 - (28%)
Similarity:79/200 - (39%) Gaps:49/200 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly   304 KRDPHISHGIYANENRRKAVGGG---GGSDSDSGTDSDGDAAA-------PSKNK---------- 348
            |.|..:...|..|.::|...|||   |.:.|..|......|||       |.:|:          
Mouse     4 KMDMSLDDIIKLNRSQRGGRGGGRGRGRAGSQGGRGGAVQAAARVNRGGGPMRNRPAIARGAAGG 68

  Fly   349 -RRSPSPLSLRTSNTKD-------------------GYRLLVSNLHTNVTTADIRELFSDIGPV- 392
             |..|:|.| |.....|                   |.:||||||...|:.|||:|||::.|.: 
Mouse    69 GRNRPAPYS-RPKQLPDKWQHDLFDSGFGGGAGVETGGKLLVSNLDFGVSDADIQELFAEFGTLK 132

  Fly   393 -----YDARVVRPGTAEVIYKSLEHAEKAVDTYHHRQFDDQPMHCVLVNPH--SSRRSVHKASSR 450
                 ||......|||:|.::....|.||:..|:....|.:||:..||...  :.||.....:..
Mouse   133 KAAVHYDRSGRSLGTADVHFERKADALKAMKQYNGVPLDGRPMNIQLVTSQIDTQRRPAQSINRG 197

  Fly   451 TVTTN 455
            .:|.|
Mouse   198 GMTRN 202

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6961NP_573325.1 RRM 256..>443 CDD:223796 53/186 (28%)
RRM_SKAR 366..434 CDD:241125 27/73 (37%)
AlyrefNP_035698.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..83 21/79 (27%)
Sufficient for RNA-binding, interaction with NXF1-NXT1 heterodimer. /evidence=ECO:0000250 16..37 7/20 (35%)
RRM_THOC4 106..179 CDD:241124 27/72 (38%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 185..255 3/17 (18%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0533
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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