DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6961 and aly-2

DIOPT Version :9

Sequence 1:	NP_573325.1	Gene:	CG6961 / 32869	FlyBaseID:	FBgn0030959	Length:	474	Species:	Drosophila melanogaster
Sequence 2:	NP_501594.1	Gene:	aly-2 / 177738	WormBaseID:	WBGene00000121	Length:	227	Species:	Caenorhabditis elegans

Alignment Length:	158	Identity:	36/158 - (22%)
Similarity:	63/158 - (39%)	Gaps:	26/158 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   306 DPHISHGIYANENRRKAV------GGGG----GSDSDSGT---DSDGDAAAPSK---NKRRSPSP 354
            |..:|..|..|...:|.|      ..||    |:.|:.||   .|.|.:....:   ..|||..
Worm     8 DMSLSDIISTNRKNKKVVKKPIKKSAGGIRKRGNASNVGTPRRQSGGTSRGGGRMGNTVRRSAG- 71

  Fly   355 LSLRTSNTKDGYRLLVSNLHTNVTTADIRELFS-----DIGPVYDARVVRPGTAEVIYKSLEHAE 414
               .:||.....|:.:|||...|.::|::|||.     .:...::......||.::..|..: |:
Worm    72 ---GSSNDNKQVRINISNLAETVISSDLQELFGAFNLHKVSVNFNENGGAAGTGDITLKKYD-AD 132

  Fly   415 KAVDTYHHRQFDDQPMHCVLVNPHSSRR 442
            :.:..:.....|.:.||..::...:..|
Worm   133 RLIQKFAGVALDGKVMHFAVIESSNFAR 160

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6961	NP_573325.1	RRM	256..>443	CDD:223796	36/158 (23%)
CG6961	NP_573325.1	RRM_SKAR	366..434	CDD:241125	16/72 (22%)
aly-2	NP_501594.1	RRM_SF	81..152	CDD:388407	16/71 (23%)
aly-2	NP_501594.1	FoP_duplication	165..>227	CDD:372765
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165197
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0533
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.700