Protein Alignment CG18259 and RBM23

DIOPT Version :10

• Sequence 1: NP_573324.1
• Gene: CG18259 / 32866
• FlyBaseID: FBgn0030956
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: NP_001339693.1
• Gene: RBM23 / 55147
• HGNCID: 20155
• Length: 483
• Species: Homo sapiens
• Alignment Length: 456
• Identity: 88/456 - (19%)
• Similarity: 149/456 - (32%)
• Gaps: 153/456 - (33%)

  Fly     2 DIDLSLDEIIERKRGQRGYRPLDRKFNANFSKPRQLLNKPFFKPSGARGSHSDTPAKRTFDARNT 66
            |.|:.::.::|        .|..::.:   .:.|:.:.|.:  ||....|.|::..:.:  ..:|
Human    49 DFDIVIEAMLE--------APYKKEED---EQQRKEVKKDY--PSNTTSSTSNSGNETS--GSST 98

  Fly    67 IAAKTRAKIADARDLINKSVRDSGIDARQLLLERKKARSAGPILIDDEEESFEPSHRARGKGVHI 131
            |...::.|.:.:.   ||| ||           ||::||.      |.:.....:.|:|..|
Human    99 IGETSKKKRSRSH---NKS-RD-----------RKRSRSR------DRDRYRRRNSRSRSPG--- 139

  Fly   132 GQFGHRLSMSNHADGTIQAKWDSDDGVVELG-NHMLSGLRRTFDPRSHKPGKPFAP-RRYIDLDN 194
            .|..||           ...||...|..... :|     ||  :.|.|....|.|. .||
Human   140 RQCRHR-----------SRSWDRRHGSESRSRDH-----RR--EDRVHYRSPPLATGYRY----- 181

  Fly   195 MQDLEDEEISRTLHLGQMKQASPRYSIGGLDLNRGDDVEMSMAPLNNKIDN---------NAFSI 250
                           |..|  ||.:              ...:|:...:||         ..|.:
Human   182 ---------------GHSK--SPHF--------------REKSPVREPVDNLSPEERDARTVFCM 215

  Fly   251 YEAARNRIERPSLTNRLVVGRSNTTKEPLERRHRDTASTSKLPESLRSRLFVGKRDPHISHGI-Y 314
            ..|||                         .|.||..........:|....:..|:...|.|| |
Human   216 QLAAR-------------------------IRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAY 255

  Fly   315 AN----ENRRKAVGGGGARDSDSGTDSDGDAAAPSKNKRRSPSPLSLRTSNTKDG----YRLLVS 371
            ..    ::...|:|..|.|  ..|......|:...||:      |:...:|.:.|    .||.|.
Human   256 VEFCEIQSVPLAIGLTGQR--LLGVPIIVQASQAEKNR------LAAMANNLQKGNGGPMRLYVG 312

  Fly   372 NLHTNVTTADIRELFSDIGPVYDARVVR-------PGTAEVIYKSLEHAEKAVDTYHHRQFDDQP 429
            :||.|:|...:|.:|...|.:.:..:::       .|...:.:...|.|.:|::..:..:...:|
Human   313 SLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFELAGRP 377

  Fly   430 M 430
            |
Human   378 M 378

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18259	NP_573324.1	RRM_SKAR	366..434	CDD:410082	16/72 (22%)
RBM23	NP_001339693.1	SF-CC1	143..482	CDD:273721	61/323 (19%)