DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18259 and SPBC106.12c

DIOPT Version :9

Sequence 1:	NP_573324.1	Gene:	CG18259 / 32866	FlyBaseID:	FBgn0030956	Length:	474	Species:	Drosophila melanogaster
Sequence 2:	NP_595161.1	Gene:	SPBC106.12c / 2540184	PomBaseID:	SPBC106.12c	Length:	274	Species:	Schizosaccharomyces pombe

Alignment Length:	230	Identity:	55/230 - (23%)
Similarity:	80/230 - (34%)	Gaps:	62/230 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   273 NTTKEPLERRH-RDTASTSKLPESLRSRL-FVGKRDPHISHGIYANENRRKAVGGGGARDSDSGT 335
            |......:.:| |...|.:::  |.:||| :..||        .:.|:......|....|.|.
pombe    12 NERTNGFDHKHSRRRGSQNRI--SKKSRLTYKFKR--------ASKEHNSSPDDGPWQHDLDQ-- 64

  Fly   336 DSDGDAAAPSKNKRRSPSPLSLRTSNTKDGYRLLVSNLHTNVTTADIRELFSDIGPV-----YDA 395
            :.|.........||:.        |..:.|.|  |.|||..|...|:..||.:..|:     ||.
pombe    65 EQDAHPRTTHLQKRQH--------SENRFGVR--VENLHYQVLEKDVLSLFENFHPIRVIMNYDR 119

  Fly   396 RVVRPGTAEVIYKSLEHAEKAVDTYHHRQ----------------FD---DQPMHCVLVNPHSSR 441
            .....|:.:|.:::.:.||.|..|.....                ||   |.| |.......|||
pombe   120 AGRSEGSCDVYFETSQDAEDAQKTLQSTNLKGSEIQISKKSPPSLFDRISDMP-HSARKPSRSSR 183

  Fly   442 ------RSVHK------ASSRTVTTNSSGVEVDID 464
                  ||..|      :||:..:.||...| |:|
pombe   184 SNRGFNRSSKKDDRSFRSSSKKSSNNSISHE-DLD 217

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18259	NP_573324.1	RRM	<345..>443	CDD:223796	30/127 (24%)
CG18259	NP_573324.1	RRM_SKAR	366..434	CDD:241125	23/91 (25%)
SPBC106.12c	NP_595161.1	RRM	1..229	CDD:223796	55/230 (24%)
SPBC106.12c	NP_595161.1	RRM_Aly_REF_like	87..158	CDD:240864	18/72 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0533
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.770