Protein Alignment CCKLR-17D3 and galr2b

DIOPT Version :10

• Sequence 1: NP_001097023.1
• Gene: CCKLR-17D3 / 32864
• FlyBaseID: FBgn0030954
• Length: 584
• Species: Drosophila melanogaster
• Sequence 2: NP_001410737.1
• Gene: galr2b / 798737
• ZFINID: ZDB-GENE-131121-48
• Length: 378
• Species: Danio rerio
• Alignment Length: 478
• Identity: 109/478 - (22%)
• Similarity: 179/478 - (37%)
• Gaps: 138/478 - (28%)

  Fly    91 SSSPSPSSTPASSSSTSTGMPVWLIPSYSMILLFAVLGNLLVISTLVQNRRM-RTITNVFLLNLA 154
            ::|.|....|||         |.:...:|:|.|...:||.||::.|:::.:: ...||:|:|||:
Zfish    15 NASESYQLNPAS---------VIVSVVFSLIFLLGTIGNSLVLAVLLRSGQVGYNTTNLFILNLS 70

  Fly   155 ISDMLLGVLCMPVTLVGTLLRNFIFGEFLCKLFQFSQAASVAVSSWTLVAISCERYYAICHPLRS 219
            ::|....:.|:|.......|..::||.|:||:..|....::..||:||.|:|.:||.||.:||||
Zfish    71 VADFFFIIFCVPFQATIYSLEGWVFGSFMCKVVHFFINLTMYASSFTLAAVSVDRYLAIRYPLRS 135

  Fly   220 RSWQTISHAYKIIGFIWLGGILCMTPIAVFSQLIPTSRPGYCKCREFWPDQGYELFYNILLD--- 281
            |..:|..:|...:..||...::...|...:..||.......|.       .|:|.....:||
Zfish   136 RELRTPCNAVVAMVVIWGLSLVFAGPYLSYYDLIDFENSNVCV-------PGWEEHNRKVLDTCT 193

  Fly   282 FLL-LVLPLLVLCVAYILITRTL-YVGMAKDSGRILQQSLPVSATTAGGSAPNPGTSSSSNCILV 344
            |:. .|:|:|::.::|   |||: |:..|.|                    |..|.|.|.
Zfish   194 FVFGYVIPVLIVSLSY---TRTIKYLWTAVD--------------------PLDGMSESK----- 230

  Fly   345 LTATAVYNENSNNNNGNSEGSAGGGSTNMATTTLTTRPTAPTVITTTTTTTVTLAKTSSPSIRVH 409
                                                                             
Zfish   231 ----------------------------------------------------------------- 230

  Fly   410 DAALRRSNEAKTLESKKRVVKMLFVLVLEFFICWTPLYVINTMVMLIGPVVYEYVDYTAISFLQL 474
                         .:|::|.||:.::.:.|.|||.|.:|: .:..|.|...:....|........
Zfish   231 -------------RAKRKVTKMIIIVTVLFCICWLPYHVV-ILCYLYGDFPFNQTTYAFRLLSHC 281

  Fly   475 LAYSSSCCNPITYCFMNASFRRAFVDTFKGLPWRRG------AGASGGVGGAAGGGLSASQAGAG 533
            :||::||.|||.|..::..||:.|...|..:..::|      ...:..|.|...|....||...
Zfish   282 MAYANSCLNPIVYALVSKHFRKGFKKVFSCILSKKGRNKVHVVNVANTVPGFEAGSTEVSQMNE- 345

  Fly   534 PGAYASANTNISLNPGLAMGMGT 556
              ..|..|.:..:|..||....|
Zfish   346 --ENARQNESEMVNRPLAQPQDT 366

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D3	NP_001097023.1	7tm_GPCRs	112..498	CDD:475119	90/391 (23%)
		TM helix 1	114..138	CDD:320334	8/23 (35%)
		TM helix 2	147..169	CDD:320334	8/21 (38%)
		TM helix 3	185..207	CDD:320334	7/21 (33%)
		TM helix 4	230..246	CDD:320334	2/15 (13%)
		TM helix 5	274..297	CDD:320334	6/26 (23%)
		TM helix 6	429..451	CDD:320334	8/21 (38%)
		TM helix 7	466..491	CDD:320334	9/24 (38%)
galr2b	NP_001410737.1	7tmA_Gal2_Gal3_R	27..305	CDD:320225	90/391 (23%)
		TM helix 1	28..54	CDD:320225	8/25 (32%)
		TM helix 2	62..88	CDD:320225	9/25 (36%)
		TM helix 3	100..130	CDD:320225	12/29 (41%)
		TM helix 4	142..162	CDD:320225	3/19 (16%)
		TM helix 5	186..215	CDD:320225	10/31 (32%)
		TM helix 6	231..261	CDD:320225	10/30 (33%)
		TM helix 7	273..298	CDD:320225	9/24 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	339..362		6/25 (24%)