Protein Alignment CCKLR-17D3 and npy2rl

DIOPT Version :10

• Sequence 1: NP_001097023.1
• Gene: CCKLR-17D3 / 32864
• FlyBaseID: FBgn0030954
• Length: 584
• Species: Drosophila melanogaster
• Sequence 2: NP_001314731.1
• Gene: npy2rl / 795311
• ZFINID: ZDB-GENE-111115-4
• Length: 373
• Species: Danio rerio
• Alignment Length: 425
• Identity: 103/425 - (24%)
• Similarity: 172/425 - (40%)
• Gaps: 117/425 - (27%)

  Fly    87 SLGTSSSPSPSSTPASSSSTST---GMPVWLIPSYSMILLFAVLGNLLVISTLVQNRRMRTITNV 148
            |:|..||....:.|......||   |:.|.||.:||.|:|..|:||.|||..:.:.:.:||:||.
Zfish    17 SIGEDSSDLTLNHPLLELGDSTKLLGVQVVLILAYSTIILLGVVGNSLVIYVVYKFKTLRTVTNF 81

  Fly   149 FLLNLAISDMLLGVLCMPVTLVGTLLRNFIFGEFLCKLFQFSQAASVAVSSWTLVAISCERYYAI 213
            |:.|||::|:|:..||:|.||..||||.:.||:.||....::|..:|.||:.||..|:.:|:..|
Zfish    82 FIANLAVADLLVNTLCLPFTLAYTLLREWKFGQVLCFTLPYAQGLAVHVSTITLNVIALDRHRCI 146

  Fly   214 CHPLRSRSWQTISHAYKIIGFIWLGGILCMTPIAVFSQ--LIPTSRPGYCK-CREFWPDQGYE-L 274
            .:.|.:|  .:....:.:|...|:...:..:|:|:|.:  ::..|.....: |.|.|||...: .
Zfish   147 VYHLDTR--MSKDTCFLVIAITWVVSAVLASPLAIFREYGIVDLSPDNSIEVCGEKWPDSSTDST 209

  Fly   275 FYNILLDFLLLVLPLLVLCVAYILITRTLYVGMAKDSGRILQQSLPVSATTAGGSAPNPGTSSSS 339
            .|:|....|..||||.::..|||.|...|
Zfish   210 LYSISTLLLQYVLPLAIISFAYIRIWSKL------------------------------------ 238

  Fly   340 NCILVLTATAVYNENSNNNNGNSEGSAGGGSTNMATTTLTTRPTAPTVITTTTTTTVTLAKTSSP 404
                                                                             
Zfish   239 ----------------------------------------------------------------- 238

  Fly   405 SIRVHDAALRRSNEAKTLESKKRVVKMLFVLVLEFFICWTPLYVINTMVMLIGPVVYEYVDYTAI 469
              |.|.:.:.|::..   ..:::..|||..:|:.|.:.|.|.:... :.:.|...|.:..|:..:
Zfish   239 --RNHVSPVGRNDRH---HRRRKTTKMLVTMVVVFAVSWLPFHAFQ-LAIDIDHSVLDMKDFRLL 297

  Fly   470 -SFLQLLAYSSSCCNPITYCFMNASFRRAFVDTFK 503
             :...::|..|:..||:.|.:||.::|.|||..|:
Zfish   298 YTVFHIVAMCSTFANPLLYGWMNRNYRSAFVAVFR 332

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D3	NP_001097023.1	7tm_GPCRs	112..498	CDD:475119	91/390 (23%)
		TM helix 1	114..138	CDD:320334	12/23 (52%)
		TM helix 2	147..169	CDD:320334	10/21 (48%)
		TM helix 3	185..207	CDD:320334	7/21 (33%)
		TM helix 4	230..246	CDD:320334	2/15 (13%)
		TM helix 5	274..297	CDD:320334	8/22 (36%)
		TM helix 6	429..451	CDD:320334	7/21 (33%)
		TM helix 7	466..491	CDD:320334	5/25 (20%)
npy2rl	NP_001314731.1	7tm_GPCRs	45..327	CDD:475119	91/390 (23%)
		TM helix 1	47..71	CDD:410628	12/23 (52%)
		TM helix 2	80..102	CDD:410628	10/21 (48%)
		TM helix 3	118..140	CDD:410628	7/21 (33%)
		TM helix 4	161..177	CDD:410628	2/15 (13%)
		TM helix 5	209..232	CDD:410628	8/22 (36%)
		TM helix 6	258..280	CDD:410628	7/22 (32%)
		TM helix 7	295..320	CDD:410628	5/24 (21%)