Protein Alignment CCKLR-17D3 and npy1r

DIOPT Version :10

• Sequence 1: NP_001097023.1
• Gene: CCKLR-17D3 / 32864
• FlyBaseID: FBgn0030954
• Length: 584
• Species: Drosophila melanogaster
• Sequence 2: NP_001095861.1
• Gene: npy1r / 793668
• ZFINID: ZDB-GENE-080221-1
• Length: 380
• Species: Danio rerio
• Alignment Length: 394
• Identity: 98/394 - (24%)
• Similarity: 155/394 - (39%)
• Gaps: 121/394 - (30%)

  Fly   117 SYSMILLFAVLGNLLVISTLVQNRRMRTITNVFLLNLAISDMLLGVLCMPVTLVGTLLRNFIFGE 181
            :||.::|..|:|||.:|..:.:.|.:..:|||.:.||::||:|:.|:|:|.|.:.|.:.:::||.
Zfish    52 AYSAVVLLGVIGNLALILVIARQRELHNVTNVLIANLSVSDLLMAVVCLPFTFIYTFMDHWVFGA 116

  Fly   182 FLCKLFQFSQAASVAVSSWTLVAISCERYYAICHPLRSRSWQ-TISHAYKIIGFIWLGGILCMTP 245
            .:|||....|..||:||.::||.|:.||:..|.||   |.|: :::||...|...|...:|..||
Zfish   117 VMCKLNSLVQCCSVSVSIFSLVLIAIERHQLILHP---RGWRPSLNHACLGISLTWALAVLTATP 178

  Fly   246 IAVFSQLIPTSRP-------------GYCKCREFWPDQGYELFYNILLDFLLLVLPLLVLCVAYI 297
            ..:||::  |..|             |...|.|.||.:..:|.|...:..|..:.||..:.:.|:
Zfish   179 FLLFSRV--TDAPLKQLPSVFQEQYRGKVVCVEEWPSREIKLTYTTGMLVLQYITPLTFIFICYL 241

  Fly   298 LITRTLYVGMAKDSGRILQQSLPVSATTAGGSAPNPGTSSSSNCILVLTATAVYNENSNNNNGNS 362
                                                               .:|......||...
Zfish   242 ---------------------------------------------------KIYTRLQRRNNMME 255

  Fly   363 EGSAGGGSTNMATTTLTTRPTAPTVITTTTTTTVTLAKTSSPSIRVHDAALRRSNEAKTLESKKR 427
                                                        |:      |.|:.::.|| ||
Zfish   256 --------------------------------------------RI------RENKYRSSES-KR 269

  Fly   428 VVKMLFVLVLEFFICWTPLYVINTMVMLIGPVVYEYVDYTAISFLQLLAYSSSCCNPITYCFMNA 492
            :..|||.:|:.|.:||.||.|.|.::.....|..........|...|.|..|.|.||:.|.|:|.
Zfish   270 INIMLFSIVVAFAVCWLPLNVFNAVIDWNHEVAMNCTHNLLFSLCHLTAMCSVCINPVFYGFLNR 334

  Fly   493 SFRR 496
            :|:|
Zfish   335 NFQR 338

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D3	NP_001097023.1	7tm_GPCRs	112..498	CDD:475119	98/394 (25%)
		TM helix 1	114..138	CDD:320334	8/20 (40%)
		TM helix 2	147..169	CDD:320334	10/21 (48%)
		TM helix 3	185..207	CDD:320334	10/21 (48%)
		TM helix 4	230..246	CDD:320334	4/15 (27%)
		TM helix 5	274..297	CDD:320334	5/22 (23%)
		TM helix 6	429..451	CDD:320334	10/21 (48%)
		TM helix 7	466..491	CDD:320334	9/24 (38%)
npy1r	NP_001095861.1	7tmA_NPY1R	47..340	CDD:320517	98/394 (25%)
		TM helix 1	48..74	CDD:320517	8/21 (38%)
		TM helix 2	81..106	CDD:320517	12/24 (50%)
		TM helix 3	119..149	CDD:320517	13/29 (45%)
		TM helix 4	160..181	CDD:320517	7/20 (35%)
		TM helix 5	217..246	CDD:320517	7/79 (9%)
		TM helix 6	265..295	CDD:320517	15/30 (50%)
		TM helix 7	308..333	CDD:320517	9/24 (38%)