Protein Alignment CCKLR-17D3 and sstr3

DIOPT Version :10

• Sequence 1: NP_001097023.1
• Gene: CCKLR-17D3 / 32864
• FlyBaseID: FBgn0030954
• Length: 584
• Species: Drosophila melanogaster
• Sequence 2: XP_695365.1
• Gene: sstr3 / 566989
• ZFINID: ZDB-GENE-061009-35
• Length: 480
• Species: Danio rerio
• Alignment Length: 403
• Identity: 92/403 - (22%)
• Similarity: 157/403 - (38%)
• Gaps: 121/403 - (30%)

  Fly   102 SSSSTSTGMPVWLIP-SYSMILLFAVLGNLLVISTLVQNRRMRTITNVFLLNLAISDMLLGVLCM 165
            :.:.|.|.|...||| .|.::.:..:.||.|||..::...:..::||:::|||||:|.|. :|.:
Zfish    47 AGNRTETSMAGILIPLIYIIVCIVGLGGNSLVIHIVLHYSKTESVTNIYILNLAIADELF-MLGL 110

  Fly   166 PVTLVGTLLRNFIFGEFLCKLFQFSQAASVAVSSWTLVAISCERYYAICHPLRSRSWQTISHAYK 230
            |...|...:.::.||.|.|:|.......:...|.:.|..:|.:||.|:.||:||..|:....|..
Zfish   111 PFLAVQNAMHSWPFGSFTCRLVMTVDGINQFTSIFCLTVMSIDRYLAVVHPIRSSKWRRPQVAKA 175

  Fly   231 IIGFIWLGGILCMTPIAVFSQLIPTSRPGYCKCREFWPDQGYE-----LFYNILLDFLLLVLPLL 290
            :.|.||....|.:.|:.:|:.:   .|.|.. |...||.....     :.|...:.|.   .|||
Zfish   176 VNGTIWAVSFLVVLPVVIFASV---QREGGI-CNIIWPKPANVWAAAFIIYTSTVGFF---FPLL 233

  Fly   291 VLCVAYILITRTLYVGMAKDSGRILQQSLPVSATTAGGSAPNPGTSSSSNCILVLTATAVYNENS 355
            |:|:.|:||
Zfish   234 VICMCYLLI-------------------------------------------------------- 242

  Fly   356 NNNNGNSEGSAGGGSTNMATTTLTTRPTAPTVITTTTTTTVTLAKTSSPSIRVHDAALRRSNEAK 420
                                                      :.|..|...:||..:.:|.
Zfish   243 ------------------------------------------VIKIRSSGKKVHATSTKRR---- 261

  Fly   421 TLESKKRVVKMLFVLVLEFFICWTPLYVINTMVMLIGPVVYEYVDYTAISFLQLLAYSSSCCNPI 485
              :|:::|.:|:.::|..|..||.|.|.:| ::.|:..:..|  ......|:.:|:|::||.|||
Zfish   262 --KSERKVTRMVVIVVAVFVFCWMPFYALN-IINLVESLRDE--PQGLHLFVVVLSYANSCANPI 321

  Fly   486 TYCFMNASFRRAF 498
            .|.|::.:|:|.|
Zfish   322 VYGFLSDNFKRGF 334

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D3	NP_001097023.1	7tm_GPCRs	112..498	CDD:475119	88/391 (23%)
		TM helix 1	114..138	CDD:320334	9/24 (38%)
		TM helix 2	147..169	CDD:320334	10/21 (48%)
		TM helix 3	185..207	CDD:320334	3/21 (14%)
		TM helix 4	230..246	CDD:320334	4/15 (27%)
		TM helix 5	274..297	CDD:320334	7/22 (32%)
		TM helix 6	429..451	CDD:320334	7/21 (33%)
		TM helix 7	466..491	CDD:320334	10/24 (42%)
sstr3	XP_695365.1	7tmA_SSTR3	58..334	CDD:320638	88/390 (23%)
		TM helix 1	59..85	CDD:320638	9/25 (36%)
		TM helix 2	92..118	CDD:320638	12/26 (46%)
		TM helix 3	129..159	CDD:320638	8/29 (28%)
		TM helix 4	171..193	CDD:320638	6/21 (29%)
		TM helix 5	216..245	CDD:320638	10/129 (8%)
		TM helix 6	262..292	CDD:320638	10/30 (33%)
		TM helix 7	302..327	CDD:320638	10/24 (42%)