Protein Alignment CCKLR-17D3 and npffr1l1

DIOPT Version :10

• Sequence 1: NP_001097023.1
• Gene: CCKLR-17D3 / 32864
• FlyBaseID: FBgn0030954
• Length: 584
• Species: Drosophila melanogaster
• Sequence 2: NP_001165167.1
• Gene: npffr1l1 / 559950
• ZFINID: ZDB-GENE-091118-18
• Length: 398
• Species: Danio rerio
• Alignment Length: 414
• Identity: 101/414 - (24%)
• Similarity: 161/414 - (38%)
• Gaps: 143/414 - (34%)

  Fly   107 STGMPVWLIPSYSMILLFAVLGNLLVISTLVQNRRMRTITNVFLLNLAISDMLLGVLCMPVTLVG 171
            |.||.|..|.||.::||..|:||.||...:::||.||::||:|:||||:||:|:|:.|:|.||:.
Zfish    27 SAGMAVSYILSYLLVLLLCVVGNGLVCLVVIRNRNMRSVTNLFILNLAVSDLLVGIFCVPTTLID 91

  Fly   172 TLLRNFIFGEFLCKLFQFSQAASVAVSSWTLVAISCERYYAICHPLRSRSWQTISHAYKIIGFIW 236
            :|:..:.|.:..|.:....|..||:.|.:|||||:.:|:..|.:|...| .:.::..:.|: |||
Zfish    92 SLISGWPFSQITCTMSNLVQGMSVSASVFTLVAIAVDRFTGIVYPFHHR-LRPVTALFAIV-FIW 154

  Fly   237 LGGILCMTPIAVF--------------SQLIPTSRPGYCKCREFWPDQGYELFYNILLDFLLLVL 287
            |.....:.|.|..              .|:.|     ...|.|.||.......|..::...:.:.
Zfish   155 LLAFAIIFPSAATLTVIHLDDMYMVQNDQIYP-----LFVCFEDWPRADMRRVYTTVIFVHVYLA 214

  Fly   288 PLLVLCVAYILITRTLYVGMAKDSGRILQQSLPVSATTAGGSAPNPGTSSSSNCILVLTATAVYN 352
            ||.::.:.|                                           .||
Zfish   215 PLGLISIMY-------------------------------------------GCI---------- 226

  Fly   353 ENSNNNNGNSEGSAGGGSTNMATTTLTTRPTAPTVITTTTTTTVTLAKTSSPSIRVHDAALRRSN 417
                         |...|:|:....|.:|
Zfish   227 -------------AAKLSSNLQENRLRSR------------------------------------ 242

  Fly   418 EAKTLESKKRVVKMLFVLVLEFFICWTPLYVINTMVMLIGPVVYEYVDYTAISFL--------QL 474
                  .:.:|:|||.::.:.|.:.|.||:   |:::|..   |:.:|...|.||        ..
Zfish   243 ------RRMKVIKMLIMVAVLFMVSWLPLW---TLMLLTD---YQDLDRQQIDFLSSYLFPVAHW 295

  Fly   475 LAYSSSCCNPITYCFMNASFRRAF 498
            ||:.:|..|||.|.|.|.:|||.|
Zfish   296 LAFFNSGVNPIIYGFFNENFRRGF 319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D3	NP_001097023.1	7tm_GPCRs	112..498	CDD:475119	97/407 (24%)
		TM helix 1	114..138	CDD:320334	10/23 (43%)
		TM helix 2	147..169	CDD:320334	12/21 (57%)
		TM helix 3	185..207	CDD:320334	9/21 (43%)
		TM helix 4	230..246	CDD:320334	5/15 (33%)
		TM helix 5	274..297	CDD:320334	3/22 (14%)
		TM helix 6	429..451	CDD:320334	7/21 (33%)
		TM helix 7	466..491	CDD:320334	11/32 (34%)
npffr1l1	NP_001165167.1	7tm_GPCRs	32..319	CDD:475119	97/407 (24%)
		TM helix 1	34..58	CDD:320647	10/23 (43%)
		TM helix 2	67..89	CDD:320647	12/21 (57%)
		TM helix 3	105..127	CDD:320647	9/21 (43%)
		TM helix 4	148..164	CDD:320647	5/16 (31%)
		TM helix 5	201..224	CDD:320647	4/65 (6%)
		TM helix 6	248..270	CDD:320647	8/24 (33%)
		TM helix 7	287..312	CDD:320647	8/24 (33%)