Protein Alignment CCKLR-17D3 and tacr3a

DIOPT Version :10

• Sequence 1: NP_001097023.1
• Gene: CCKLR-17D3 / 32864
• FlyBaseID: FBgn0030954
• Length: 584
• Species: Drosophila melanogaster
• Sequence 2: NP_001243567.1
• Gene: tacr3a / 555482
• ZFINID: ZDB-GENE-090312-106
• Length: 399
• Species: Danio rerio
• Alignment Length: 420
• Identity: 108/420 - (25%)
• Similarity: 170/420 - (40%)
• Gaps: 120/420 - (28%)

  Fly   101 ASSSSTSTG-------MPVWLIP----SYSMILLFAVLGNLLVISTLVQNRRMRTITNVFLLNLA 154
            :.:.|..||       .|.|.:.    :||.||..||.|||:|:..::.::||||:||.||||||
Zfish     4 SQNGSNLTGNFTNQFVQPPWRVALWSVAYSSILAIAVFGNLIVMWIILAHKRMRTVTNYFLLNLA 68

  Fly   155 ISDMLLGVLCMPVTLVGTLLRNFIFGEFLCKLFQFSQAASVAVSSWTLVAISCERYYAICHPLRS 219
            .||..:......:..|.....::.|||..||...|....||..|.:::.||:.:||.||.|||:.
Zfish    69 FSDASMAAFNTLINFVYATHGDWYFGEAYCKFHNFFPVTSVFASIYSMSAIAVDRYMAIIHPLKP 133

  Fly   220 RSWQTISHAYKIIGFIWLGGILCMTPIAVFSQLIPTSRPGYCKCREFWPDQGYELF-YNILLDFL 283
            |...|.:..  ||..||:..::...|:..||.:  ...|....|...||....:.| |:|::..|
Zfish   134 RLSATATKV--IIVCIWVLAVVLAFPLCFFSTI--KKLPKRTLCYVAWPRPSEDPFMYHIIVAML 194

  Fly   284 LLVLPLLVLCVAYILITRTLYVGMAKDSGRILQQSLPVSATTAGGSAPNPGTSSSSNCILVLTAT 348
            :.||||:|:.:.|.::..||:                      ||..|
Zfish   195 VYVLPLVVMGINYTIVGLTLW----------------------GGEIP----------------- 220

  Fly   349 AVYNENSNNNNGNSEGSAGGGSTNMATTTLTTRPTAPTVITTTTTTTVTLAKTSSPSIRVHDAAL 413
               .::|:|..|.
Zfish   221 ---GDSSDNYQGQ---------------------------------------------------- 230

  Fly   414 RRSNEAKTLESKKRVVKMLFVLVLEFFICWTPLYVINTMVMLIGPVV-YEYVDYTAISFLQLLAY 477
                    |.:|::||||:.::|:.|..||.|.:|...:..|...:. ::::....:| :..||.
Zfish   231 --------LRAKRKVVKMMIIVVVTFAFCWLPYHVYFLVTGLNKQLARWKFIQQIYLS-IMWLAM 286

  Fly   478 SSSCCNPITYCFMNASFRRAFVDTFKGLPW 507
            ||:..|||.||.:|:.||..|...|:..|:
Zfish   287 SSTMYNPIIYCCLNSRFRAGFKRVFRWCPF 316

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D3	NP_001097023.1	7tm_GPCRs	112..498	CDD:475119	101/391 (26%)
		TM helix 1	114..138	CDD:320334	10/27 (37%)
		TM helix 2	147..169	CDD:320334	9/21 (43%)
		TM helix 3	185..207	CDD:320334	7/21 (33%)
		TM helix 4	230..246	CDD:320334	4/15 (27%)
		TM helix 5	274..297	CDD:320334	9/23 (39%)
		TM helix 6	429..451	CDD:320334	9/21 (43%)
		TM helix 7	466..491	CDD:320334	10/24 (42%)
tacr3a	NP_001243567.1	7tm_GPCRs	26..307	CDD:475119	100/387 (26%)
		TM helix 1	28..52	CDD:320669	10/23 (43%)
		TM helix 2	61..83	CDD:320669	9/21 (43%)
		TM helix 3	99..121	CDD:320669	7/21 (33%)
		TM helix 4	142..158	CDD:320669	4/17 (24%)
		TM helix 5	185..208	CDD:320669	9/22 (41%)
		TM helix 6	238..260	CDD:320669	9/21 (43%)
		TM helix 7	275..300	CDD:320669	10/25 (40%)