Protein Alignment CCKLR-17D3 and Qrfprl

DIOPT Version :10

• Sequence 1: NP_001097023.1
• Gene: CCKLR-17D3 / 32864
• FlyBaseID: FBgn0030954
• Length: 584
• Species: Drosophila melanogaster
• Sequence 2: NP_001102709.1
• Gene: Qrfprl / 500157
• RGDID: 1560028
• Length: 415
• Species: Rattus norvegicus
• Alignment Length: 395
• Identity: 87/395 - (22%)
• Similarity: 155/395 - (39%)
• Gaps: 119/395 - (30%)

  Fly   120 MILLFAVLGNLLVISTLVQNRRMRTITNVFLLNLAISDMLLGVLCMPVTLVGTLLRNFIFGEFLC 184
            :|...|:.||.||:..:.:::.|||:||:|:.:||:||:|:...|:|||::..:...::.|.|:|
  Rat    53 LIFALALFGNALVVYVVTRSKAMRTVTNIFICSLALSDLLIVFFCIPVTMLQNVSDTWLGGAFIC 117

  Fly   185 KLFQFSQAASVAVSSWTLVAISCERYYAICHPLRSRSWQTISHAYKIIGFIWLGGILCMTPIAVF 249
            |:..|.|..:|.....|:..|:.||:..:.||.:.:...|...|:.::|.:||..|:..:|:...
  Rat   118 KMVPFVQCTAVVTEILTMTCIAVERHQGLVHPFKMKQQYTNQRAFTMLGVVWLVAIIIGSPMWHV 182

  Fly   250 SQL-----IPTSRPGYCKCREFWPDQGYELFYNILLDFLLLVLPLLVLCVAYILITRTLYVGMAK 309
            .:|     ....:...| |.|.|....::..|...:...|.:||||:|.|.|..|...|::....
  Rat   183 QRLEIKYDFLYEKEHIC-CLEEWSSPVHQKIYTTFILVTLFLLPLLLLSVLYGKIGYELWIKKRV 246

  Fly   310 DSGRILQQSLPVSATTAGGSAPNPGTSSSSNCILVLTATAVYNENSNNNNGNSEGSAGGGSTNMA 374
            ..|.:|:
  Rat   247 GDGSVLR---------------------------------------------------------- 253

  Fly   375 TTTLTTRPTAPTVITTTTTTTVTLAKTSSPSIRVHDAALRRSNEAKTLESKKRVVKMLFVLVLEF 439
                                            .:|...:     .|....|||.|.|:..:|:.|
  Rat   254 --------------------------------TIHGKEM-----FKIARKKKRAVIMMVTVVVLF 281

  Fly   440 FICWTPLYVINTMVMLIGPVVYEYVDY----------TAISFLQLLAYSSSCCNPITYCFMNASF 494
            .:||.|.:|::.|:        ||.::          ...:.:|::.:.:|.||||.|..||.:|
  Rat   282 AVCWAPFHVVHMMI--------EYSNFEKEYDEVTIKMIFAIVQIIGFFNSICNPIVYALMNENF 338

  Fly   495 RRAFV 499
            ::.||
  Rat   339 KKNFV 343

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D3	NP_001097023.1	7tm_GPCRs	112..498	CDD:475119	85/392 (22%)
		TM helix 1	114..138	CDD:320334	6/17 (35%)
		TM helix 2	147..169	CDD:320334	10/21 (48%)
		TM helix 3	185..207	CDD:320334	6/21 (29%)
		TM helix 4	230..246	CDD:320334	4/15 (27%)
		TM helix 5	274..297	CDD:320334	8/22 (36%)
		TM helix 6	429..451	CDD:320334	8/21 (38%)
		TM helix 7	466..491	CDD:320334	7/34 (21%)
Qrfprl	NP_001102709.1	7tmA_QRFPR	60..342	CDD:320333	83/385 (22%)
		TM helix 2	79..105	CDD:320333	12/25 (48%)
		TM helix 3	117..147	CDD:320333	9/29 (31%)
		TM helix 4	160..181	CDD:320333	6/20 (30%)
		TM helix 5	210..235	CDD:320333	9/24 (38%)
		TM helix 6	265..295	CDD:320333	11/29 (38%)
		TM helix 7	310..335	CDD:320333	7/24 (29%)