Protein Alignment CCKLR-17D3 and npy7r

DIOPT Version :10

• Sequence 1: NP_001097023.1
• Gene: CCKLR-17D3 / 32864
• FlyBaseID: FBgn0030954
• Length: 584
• Species: Drosophila melanogaster
• Sequence 2: NP_001007219.1
• Gene: npy7r / 449010
• ZFINID: ZDB-GENE-040924-9
• Length: 372
• Species: Danio rerio
• Alignment Length: 462
• Identity: 113/462 - (24%)
• Similarity: 181/462 - (39%)
• Gaps: 141/462 - (30%)

  Fly    49 GNGGTVSLAGNATSSYGDDDRDGYMDTEPSDLVTELAFSLGTSSSPSPSSTPASSSSTSTGMPVW 113
            |:..||...||..:|.|:|..:.|......|:...|:..:.
Zfish     9 GSEDTVLHDGNQETSLGNDSVNTYKPAFVDDITKHLSVQIS------------------------ 49

  Fly   114 LIPSYSMILLFAVLGNLLVISTLVQNRRMRTITNVFLLNLAISDMLLGVLCMPVTLVGTLLRNFI 178
            ||.:||:|:|..::||.|||..::..|.|||:||.|:.|||::|:::..:|:|.|||.|||..:.
Zfish    50 LILAYSLIILLGLVGNTLVIYMIILYRNMRTVTNYFIANLALADLMVDTVCLPFTLVYTLLDEWK 114

  Fly   179 FGEFLCKLFQFSQAASVAVSSWTLVAISCERYYAICHPLRSRSWQTISHAYKIIGFIWLGGILCM 243
            ||..:|.:..:|||.||.||..||..|:.|||..|...|..|..:..|  :.|||..|....:..
Zfish   115 FGAVMCHMVPYSQALSVHVSILTLTIIALERYRCIVFHLGQRLNRCTS--FIIIGLTWAFAAILA 177

  Fly   244 TPIAVFSQL----IPTSRPGYCKCREFWPD--QGYELFYNILLDFLLLVLPLLVLCVAYILITRT 302
            .|:|:|.:.    ||........|.|.||:  ....:.|::.:..|..|:||.::..||:
Zfish   178 GPLAIFREYRYEEIPYIDLRIAVCSEKWPNGTNRDAVIYSLSMLLLQYVVPLAIISYAYV----- 237

  Fly   303 LYVGMAKDSGRILQQSLPVSATTAGGSAPNPGTSSSSNCILVLTATAVYNENSNNNNGNSEGSAG 367
                                                  ||
Zfish   238 --------------------------------------CI------------------------- 239

  Fly   368 GGSTNMATTTLTTRPTAPTVITTTTTTTVTLAKTSSPSIRVHDAALRRSNEAKTLESKKRVVKML 432
                                       .:.|....|||.| :|..:||          |:..|||
Zfish   240 ---------------------------WIKLKNHVSPSNR-NDGIVRR----------KKTTKML 266

  Fly   433 FVLVLEFFICWTPLYVINTMVMLIGPVVYEYVDYTAI-SFLQLLAYSSSCCNPITYCFMNASFRR 496
            .::|:.|.:||.|.::......|  .::.::.:|..| :...::|..|:..||:.|.:||.::|.
Zfish   267 ALVVVVFAVCWLPFHMFQLASDL--DLILKFKEYKLIYTLFHIVAMCSTFVNPLLYGWMNQNYRN 329

  Fly   497 AFVDTFK 503
            .|:..|:
Zfish   330 GFLMFFR 336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D3	NP_001097023.1	7tm_GPCRs	112..498	CDD:475119	100/392 (26%)
		TM helix 1	114..138	CDD:320334	11/23 (48%)
		TM helix 2	147..169	CDD:320334	8/21 (38%)
		TM helix 3	185..207	CDD:320334	10/21 (48%)
		TM helix 4	230..246	CDD:320334	4/15 (27%)
		TM helix 5	274..297	CDD:320334	6/22 (27%)
		TM helix 6	429..451	CDD:320334	8/21 (38%)
		TM helix 7	466..491	CDD:320334	7/25 (28%)
npy7r	NP_001007219.1	7tm_GPCRs	48..331	CDD:475119	100/416 (24%)
		TM helix 1	50..74	CDD:410628	11/23 (48%)
		TM helix 2	83..105	CDD:410628	8/21 (38%)
		TM helix 3	121..143	CDD:410628	10/21 (48%)
		TM helix 4	164..180	CDD:410628	4/15 (27%)
		TM helix 5	214..237	CDD:410628	6/22 (27%)
		TM helix 6	263..285	CDD:410628	8/21 (38%)
		TM helix 7	299..324	CDD:410628	6/24 (25%)