DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CCKLR-17D3 and SIFaR

DIOPT Version :9

Sequence 1:	NP_001097023.1	Gene:	CCKLR-17D3 / 32864	FlyBaseID:	FBgn0030954	Length:	584	Species:	Drosophila melanogaster
Sequence 2:	NP_001163674.1	Gene:	SIFaR / 42530	FlyBaseID:	FBgn0038880	Length:	758	Species:	Drosophila melanogaster

Alignment Length:	528	Identity:	132/528 - (25%)
Similarity:	207/528 - (39%)	Gaps:	176/528 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 ADQAAMAAAAAYRALLD---YYANAPSAAGHIVSLNVAPYNGTGNGGTVSL--AGNATSSYGD-- 66
            |..||...|:|..:|..   ..|:|.|:..:...||::|       .|.||  |..||.||.|
  Fly   126 ATLAATTTASARGSLAGKSLAIADATSSTYYSNLLNLSP-------ATTSLISAAAATKSYNDSA 183

  Fly    67 ---DDRDGYMDTEPSDLVTELAFSLGTSSSPSPSSTPASSSSTSTGMPVWLIPSYSMILLFAVLG 128
               :..||.:|         ..|.            |....|.:..| |:.: :|.::.|..::|
  Fly   184 LRWEQLDGSVD---------FGFD------------PLYRHSLAMSM-VYCV-AYIVVFLVGLIG 225

  Fly   129 NLLVISTLVQNRRMRTITNVFLLNLAISDMLLGVLCMPVTLVGTLLRNFIFGEFLCKLFQFSQAA 193
            |..||:.:::..||||:||.|::||||:|:|:.|.|:|.||:|.:...::.|..:||...:.|..
  Fly   226 NSFVIAVVLRAPRMRTVTNYFIVNLAIADILVIVFCLPATLIGNIFVPWMLGWLMCKFVPYIQGV 290

  Fly   194 SVAVSSWTLVAISCERYYAICHPLRSRSWQTISHAYKIIGFIWLGGILCMTPIAVFSQLIPT--- 255
            |||.|.::|:|:|.:|:.||..||:.   .|...|..:|..||:..::...|..:|..|:|.
  Fly   291 SVAASVYSLIAVSLDRFIAIWWPLKQ---MTKRRARIMIIGIWVIALVTTIPWLLFFDLVPAEEV 352

  Fly   256 ---------SRPGYCKCREFWP--DQG--YELFYNILLDFLLLVLPLLVLCVAYILI-----TRT 302
                     |:|.:. |:|.||  ..|  |.|..|::..:|   ||:.::.:.|:||     ||:
  Fly   353 FSDALVSAYSQPQFL-CQEVWPPGTDGNLYFLLANLVACYL---LPMSLITLCYVLIWIKVSTRS 413

  Fly   303 LYVGMAKDSGRILQQSLPVSATTAGGSAPNPGTSSSSNCILVLTATAVYNENSNNNNGNSEGSAG 367
            :                             ||.|.
  Fly   414 I-----------------------------PGESK------------------------------ 419

  Fly   368 GGSTNMATTTLTTRPTAPTVITTTTTTTVTLAKTSSPSIRVHDAALRRSNEAKTLESKKRVVKML 432
                                                      ||.:.|..:    :||.:|:|||
  Fly   420 ------------------------------------------DAQMDRMQQ----KSKVKVIKML 438

  Fly   433 FVLVLEFFICWTPLYVINTMVMLIGPVVYEYVDY--TAISFLQLLAYSSSCCNPITYCFMNASFR 495
            ..:|:.|.:.|.|||||...:.....:..|..:.  ..:...|.|..|:||.|||.|. :|..:|
  Fly   439 VAVVILFVLSWLPLYVIFARIKFGSDISQEEFEILKKVMPVAQWLGSSNSCINPILYS-VNKKYR 502

  Fly   496 RAFVDTFK 503
            |.|....|
  Fly   503 RGFAAIIK 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D3	NP_001097023.1	7tm_4	120..>244	CDD:304433	45/123 (37%)
CCKLR-17D3	NP_001097023.1	7tm_1	128..487	CDD:278431	95/381 (25%)
SIFaR	NP_001163674.1	7tm_4	216..>443	CDD:304433	79/338 (23%)
SIFaR	NP_001163674.1	7tm_1	225..495	CDD:278431	95/381 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45472998
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840