Protein Alignment CCKLR-17D3 and Lkr

DIOPT Version :10

• Sequence 1: NP_001097023.1
• Gene: CCKLR-17D3 / 32864
• FlyBaseID: FBgn0030954
• Length: 584
• Species: Drosophila melanogaster
• Sequence 2: NP_647968.3
• Gene: Lkr / 38622
• FlyBaseID: FBgn0035610
• Length: 542
• Species: Drosophila melanogaster
• Alignment Length: 523
• Identity: 126/523 - (24%)
• Similarity: 198/523 - (37%)
• Gaps: 188/523 - (35%)

  Fly   118 YSMILLFAVLGNLLVISTLVQNRRMRTITNVFLLNLAISDMLLGVLCMPVTLVGTLLRNFIFGEF 182
            |..|.:.||:||.|||..:...|:|||:||:::.|||.:|:::|:.|:|......||:::....|
  Fly    42 YGGISIVAVIGNTLVIWVVATTRQMRTVTNMYIANLAFADVIIGLFCIPFQFQAALLQSWNLPWF 106

  Fly   183 LCKLFQFSQAASVAVSSWTLVAISCERYYAICHPLRSRSWQTISHAYKIIGFIWLGGILCMTPIA 247
            :|....|.||.||.||.:||.||:.:|:.||.:|||:|..:.:|..  |||.||:..:|...|.|
  Fly   107 MCSFCPFVQALSVNVSVFTLTAIAIDRHRAIINPLRARPTKFVSKF--IIGGIWMLALLFAVPFA 169

  Fly   248 VF-------------SQLIPTSRPGYCKCREFWPDQGYELFYNILLDFLLLVLPLLVLCVAYILI 299
            :.             ::....:|| :|..:....||.....|.::  |:..::|..|:...||.:
  Fly   170 IAFRVEELTERFRENNETYNVTRP-FCMNKNLSDDQLQSFRYTLV--FVQYLVPFCVISFVYIQM 231

  Fly   300 TRTLYVGMAKDSGRILQQSLPVSATTAGGSAPNPGTSSSSNCILVLTATAVYNENSNNNNGNSEG 364
            ...|:                      |..||                            ||::.
  Fly   232 AVRLW----------------------GTRAP----------------------------GNAQD 246

  Fly   365 SAGGGSTNMATTTLTTRPTAPTVITTTTTTTVTLAKTSSPSIRVHDAALRRSNEAKTLESKKRVV 429
            |                            ..:||                       |::||:|:
  Fly   247 S----------------------------RDITL-----------------------LKNKKKVI 260

  Fly   430 KMLFVLVLEFFICWTPLYVINTMVMLIGPVVYEYVDYTAISFL----QLLAYSSSCCNPITYCFM 490
            |||.::|:.|.:||.||.:.|.:.:.|.    |..||..||.:    ..||.|:||.||..|...
  Fly   261 KMLIIVVIIFGLCWLPLQLYNILYVTIP----EINDYHFISIVWFCCDWLAMSNSCYNPFIYGIY 321

  Fly   491 NASFRRAFVDTFKGLPWR---------------------RGAGASGGVG------GAAGGGLSAS 528
            |..|:|.|...|.....:                     |...|:..:.      |.|.||::..
  Fly   322 NEKFKREFNKRFAACFCKFKTSMDAHERTFSMHTRASSIRSTYANSSMRIRSNLFGPARGGVNNG 386

  Fly   529 Q----------AGAGPGAY-ASANTNISLN--------------------PGLAMGMGTWRSRSR 562
            :          :||..|.| .|:..|.::|                    ||:.:.|..||   |
  Fly   387 KPGLHMPRVHGSGANSGIYNGSSGQNNNVNGQHHQHQSVVTFAATPGVSAPGVGVAMPPWR---R 448

  Fly   563 HEF 565
            :.|
  Fly   449 NNF 451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D3	NP_001097023.1	7tm_GPCRs	112..498	CDD:475119	104/396 (26%)
		TM helix 1	114..138	CDD:320334	9/19 (47%)
		TM helix 2	147..169	CDD:320334	8/21 (38%)
		TM helix 3	185..207	CDD:320334	11/21 (52%)
		TM helix 4	230..246	CDD:320334	6/15 (40%)
		TM helix 5	274..297	CDD:320334	4/22 (18%)
		TM helix 6	429..451	CDD:320334	9/21 (43%)
		TM helix 7	466..491	CDD:320334	11/28 (39%)
Lkr	NP_647968.3	7tmA_leucokinin-like	36..329	CDD:320515	104/396 (26%)
		TM helix 1	37..63	CDD:320515	9/20 (45%)
		TM helix 2	70..95	CDD:320515	9/24 (38%)
		TM helix 3	108..138	CDD:320515	14/29 (48%)
		TM helix 4	149..170	CDD:320515	8/22 (36%)
		TM helix 5	205..234	CDD:320515	6/30 (20%)
		TM helix 6	254..284	CDD:320515	13/29 (45%)
		TM helix 7	297..322	CDD:320515	9/24 (38%)