Protein Alignment CCKLR-17D3 and CCHa1-R

DIOPT Version :10

• Sequence 1: NP_001097023.1
• Gene: CCKLR-17D3 / 32864
• FlyBaseID: FBgn0030954
• Length: 584
• Species: Drosophila melanogaster
• Sequence 2: NP_611241.2
• Gene: CCHa1-R / 37004
• FlyBaseID: FBgn0050106
• Length: 499
• Species: Drosophila melanogaster
• Alignment Length: 477
• Identity: 101/477 - (21%)
• Similarity: 179/477 - (37%)
• Gaps: 169/477 - (35%)

  Fly    82 TELAFSLGTSSS--------PSPSSTP-----ASSSSTSTGMPV--------------------- 112
            |:||.::|..:|        |.|:.|.     |...|.||..|:
  Fly    10 TDLAMNIGLDTSGEAPTALPPMPNVTETLWDLAMVVSQSTQWPLLDTGSSENFSELVTTETPYVP 74

  Fly   113 -------WLIP-SYSMILLFAVLGNLLVISTLVQNRRMRTITNVFLLNLAISDMLLGVLCMPVTL 169
                   :::| .:::|.:..||||..:|...:..|:||.:.|.::|:||::|:|:.:..:|:..
  Fly    75 YGRRPETYIVPILFALIFVVGVLGNGTLIVVFLSVRQMRNVPNTYILSLALADLLVIITTVPLAS 139

  Fly   170 VGTLLRNFIFGEFLCKLFQFSQAASVAVSSWTLVAISCERYYAICHPLRS---------RSWQTI 225
            ....:..:.:|.|||.|.:|.:..|:.||.:||.|:|.:||:||..|||.         .:..|:
  Fly   140 TVYTVEYWPYGSFLCSLSEFMKDVSIGVSVFTLTALSGDRYFAIVDPLRKFHAHGGGRRATRMTL 204

  Fly   226 SHAYKIIGFIWLGGILCMTPIAVFSQL--IPTSRPGYCKCREFWPDQGYELFYN-ILLDFLL-LV 286
            :.|..    |||..|||..|..:.|.|  :..:......|..:..:.|.....: :||.||: ..
  Fly   205 ATAVS----IWLLAILCGLPALIGSNLKHLGINEKSIVICYPYPEEWGINYAKSMVLLHFLVYYA 265

  Fly   287 LPLLVLCVAYILITRTLYVGMAKDSGRILQQSLPVSATTAGGSAPNPGTSSSSNCILVLTATAVY 351
            :||:|:.|.|:||...|          :...|:|
  Fly   266 IPLVVIAVFYVLIALHL----------MYSASVP------------------------------- 289

  Fly   352 NENSNNNNGNSEGSAGGGSTNMATTTLTTRPTAPTVITTTTTTTVTLAKTSSPSIRVHDAALRRS 416
                    |..:|:
  Fly   290 --------GEIQGA--------------------------------------------------- 295

  Fly   417 NEAKTLESKKRVVKMLFVLVLEFFICWTPLYVINTMVMLIGPVVYEYVDYTAI-SFLQLLAY--- 477
              .:.:.::::|...:...|:.|.||:.|.:|. .:.....|...:  ||.|. ..|:::||
  Fly   296 --VRQVRARRKVAVTVLAFVVIFGICFLPYHVF-FLWFYFWPTAQD--DYNAFWHVLRIVAYCMS 355

  Fly   478 -SSSCCNPITYCFMNASFRRAF 498
             ::||.||:...|::.:||:.|
  Fly   356 FANSCANPVALYFVSGAFRKHF 377

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D3	NP_001097023.1	7tm_GPCRs	112..498	CDD:475119	87/432 (20%)
		TM helix 1	114..138	CDD:320334	7/24 (29%)
		TM helix 2	147..169	CDD:320334	7/21 (33%)
		TM helix 3	185..207	CDD:320334	8/21 (38%)
		TM helix 4	230..246	CDD:320334	6/15 (40%)
		TM helix 5	274..297	CDD:320334	8/24 (33%)
		TM helix 6	429..451	CDD:320334	6/21 (29%)
		TM helix 7	466..491	CDD:320334	10/29 (34%)
CCHa1-R	NP_611241.2	7tmA_Bombesin_R-like	82..377	CDD:320593	87/403 (22%)
		TM helix 1	83..109	CDD:320593	7/25 (28%)
		TM helix 2	116..142	CDD:320593	7/25 (28%)
		TM helix 3	154..184	CDD:320593	13/29 (45%)
		TM helix 4	201..221	CDD:320593	8/23 (35%)
		TM helix 5	252..277	CDD:320593	9/24 (38%)
		TM helix 6	300..330	CDD:320593	7/30 (23%)
		TM helix 7	345..370	CDD:320593	8/24 (33%)