Protein Alignment CCKLR-17D3 and AkhR

DIOPT Version :10

• Sequence 1: NP_001097023.1
• Gene: CCKLR-17D3 / 32864
• FlyBaseID: FBgn0030954
• Length: 584
• Species: Drosophila melanogaster
• Sequence 2: NP_995639.1
• Gene: AkhR / 33942
• FlyBaseID: FBgn0025595
• Length: 455
• Species: Drosophila melanogaster
• Alignment Length: 392
• Identity: 87/392 - (22%)
• Similarity: 148/392 - (37%)
• Gaps: 125/392 - (31%)

  Fly   115 IPSYSMILLFAVLGNLLVISTLVQNRRMR--TITNVFLLNLAISDMLLGVLCMPVTLVGTLLRNF 177
            |..||::.:.:.:||..|: .|:..||:|  ...::.|::|||:|:::.:|.||:.:|......:
  Fly    42 ITVYSILFVISTIGNSTVL-YLLTKRRLRGPLRIDIMLMHLAIADLMVTLLLMPMEIVWAWTVQW 105

  Fly   178 IFGEFLCKLFQFSQAASVAVSSWTLVAISCERYYAICHPLRSRSWQTISHAYKIIGFIWLGGILC 242
            :..:.:|:|..|.:...:.:||:.:|.||.:||:||..||: ||:   :....::...|||.::|
  Fly   106 LSTDLMCRLMSFFRVFGLYLSSYVMVCISLDRYFAILKPLK-RSY---NRGRIMLACAWLGSVVC 166

  Fly   243 MTPIAVFSQLIPTSRP---GYCKC---REFWPDQGYELFYNILLDFLLLVLPLLVLCVAYILITR 301
            ..|.|....|  ...|   ||.:|   ..|..|.. |..|.......:...||::....|    .
  Fly   167 SIPQAFLFHL--EEHPAVTGYFQCVIFNSFRSDFD-EKLYQAASMCSMYAFPLIMFIYCY----G 224

  Fly   302 TLYVGMAKDSGRILQQSLPVSATTAGGSAPNPGTSSSSNCILVLTATAVYNENSNNNNGNSEGSA 366
            .:|:.:.:.|.|:|:.
  Fly   225 AIYLEIYRKSQRVLKD------------------------------------------------- 240

  Fly   367 GGGSTNMATTTLTTRPTAPTVITTTTTTTVTLAKTSSPSIRVHDAALRRSNEAKTLESKKRVVKM 431
                                                     |.....||||:.....:|||.:||
  Fly   241 -----------------------------------------VIAERFRRSNDDVLSRAKKRTLKM 264

  Fly   432 LFVLVLEFFICWTPLYVINTMVML-------IGPVVYEYVDYTAISFLQLLAYSSSCCNPITYCF 489
            ...:|:.|.|||||.|.|:....|       |.|::.:        .|.:.|.::||.||:.|..
  Fly   265 TITIVIVFIICWTPYYTISMWYWLDKHSAGKINPLLRK--------ALFIFASTNSCMNPLVYGL 321

  Fly   490 MN 491
            .|
  Fly   322 YN 323

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D3	NP_001097023.1	7tm_GPCRs	112..498	CDD:475119	87/392 (22%)
		TM helix 1	114..138	CDD:320334	7/22 (32%)
		TM helix 2	147..169	CDD:320334	8/21 (38%)
		TM helix 3	185..207	CDD:320334	6/21 (29%)
		TM helix 4	230..246	CDD:320334	4/15 (27%)
		TM helix 5	274..297	CDD:320334	3/22 (14%)
		TM helix 6	429..451	CDD:320334	11/21 (52%)
		TM helix 7	466..491	CDD:320334	7/24 (29%)
AkhR	NP_995639.1	7tmA_AKHR	39..328	CDD:320504	87/392 (22%)
		TM helix 1	40..66	CDD:320504	7/24 (29%)
		TM helix 2	74..101	CDD:320504	9/26 (35%)
		TM helix 3	112..142	CDD:320504	11/29 (38%)
		TM helix 4	151..172	CDD:320504	5/20 (25%)
		TM helix 5	200..229	CDD:320504	6/32 (19%)
		TM helix 6	256..286	CDD:320504	14/29 (48%)
		TM helix 7	298..323	CDD:320504	8/32 (25%)