Protein Alignment CCKLR-17D3 and npy8ar

DIOPT Version :10

• Sequence 1: NP_001097023.1
• Gene: CCKLR-17D3 / 32864
• FlyBaseID: FBgn0030954
• Length: 584
• Species: Drosophila melanogaster
• Sequence 2: XP_068079825.1
• Gene: npy8ar / 30714
• ZFINID: ZDB-GENE-990415-175
• Length: 393
• Species: Danio rerio
• Alignment Length: 445
• Identity: 108/445 - (24%)
• Similarity: 172/445 - (38%)
• Gaps: 130/445 - (29%)

  Fly    81 VTELAFSLGTSSSPSPSSTPASSSSTSTGMPVWLIPSYSMILLFAVLGNLLVISTLVQNRRMRTI 145
            :|.::...|..|....:..|.|.|.|:.     ||.:||.::...::||..::..:.:.:.||.:
Zfish    25 ITNISSGTGQKSWVESNVCPPSVSGTTL-----LIVAYSTVIAVGLVGNTCLVFIISRQKEMRNV 84

  Fly   146 TNVFLLNLAISDMLLGVLCMPVTLVGTLLRNFIFGEFLCKLFQFSQAASVAVSSWTLVAISCERY 210
            ||:.:.||:.||:|:.|:|:|||::.||:..:|.||.|||:..|.|..||.||.::||.|:.||:
Zfish    85 TNILIANLSCSDILMCVVCLPVTVIYTLMDRWILGETLCKVTPFVQCMSVTVSIFSLVLIALERH 149

  Fly   211 YAICHPLRSRSW-QTISHAYKIIGFIWLGGILCMTPIAVFSQLIPTSRP------------GYCK 262
            ..|.||   ..| ....|:|..:...|:  :.|...:...|..|.|:.|            .:..
Zfish   150 QLIIHP---TGWTPAAGHSYLAVAVTWM--VACFISLPFLSFNILTNAPFQNISLPFNPFSDHVI 209

  Fly   263 CREFWPDQGYELFYNILLDFLLLVLPLLVLCVAYILITRTLYVGMAKDSGRILQQSLPVSATTAG 327
            |.|.||.:...|.|...|......||||::.:.|:.|  .|.:...||
Zfish   210 CMELWPSERNRLAYTTSLLLFQYCLPLLLILLCYLRI--FLRLRRRKD----------------- 255

  Fly   328 GSAPNPGTSSSSNCILVLTATAVYNENSNNNNGNSEGSAGGGSTNMATTTLTTRPTAPTVITTTT 392
                           :|..||
Zfish   256 ---------------MVEQAT-------------------------------------------- 261

  Fly   393 TTTVTLAKTSSPSIRVHDAALRRSNEAKTLESKKRVVKMLFVLVLEFFICWTPLYVINTMVMLIG 457
                             :|..|::..|      :||..||.|:|:.|.:||.||.|.||:.....
Zfish   262 -----------------EARQRKARGA------QRVNAMLVVIVVAFALCWLPLNVFNTIFDWYH 303

  Fly   458 PVVYEYVDYTAISFLQLLAYSSSCCNPITYCFMNASFRRAFVDTFK------GLP 506
            ..:.........|...|.|.:|:|.||:.|.|:|.:|::....|.:      |:|
Zfish   304 QALPACQHDVIFSACHLTAMASTCVNPVVYGFLNTNFQKELKATLQRCNCGWGVP 358

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D3	NP_001097023.1	7tm_GPCRs	112..498	CDD:475119	98/398 (25%)
		TM helix 1	114..138	CDD:320334	6/23 (26%)
		TM helix 2	147..169	CDD:320334	10/21 (48%)
		TM helix 3	185..207	CDD:320334	10/21 (48%)
		TM helix 4	230..246	CDD:320334	2/15 (13%)
		TM helix 5	274..297	CDD:320334	7/22 (32%)
		TM helix 6	429..451	CDD:320334	10/21 (48%)
		TM helix 7	466..491	CDD:320334	9/24 (38%)
npy8ar	XP_068079825.1	7tmA_NPY4R	51..344	CDD:320519	98/403 (24%)
		TM helix 1	52..78	CDD:320519	6/30 (20%)
		TM helix 2	85..110	CDD:320519	12/24 (50%)
		TM helix 3	123..153	CDD:320519	13/29 (45%)
		TM helix 4	164..185	CDD:320519	4/22 (18%)
		TM helix 5	220..249	CDD:320519	9/30 (30%)
		TM helix 6	269..299	CDD:320519	15/35 (43%)
		TM helix 7	312..337	CDD:320519	9/24 (38%)