Protein Alignment CCKLR-17D3 and Npy1r

DIOPT Version :10

• Sequence 1: NP_001097023.1
• Gene: CCKLR-17D3 / 32864
• FlyBaseID: FBgn0030954
• Length: 584
• Species: Drosophila melanogaster
• Sequence 2: NP_001106828.1
• Gene: Npy1r / 29358
• RGDID: 3198
• Length: 382
• Species: Rattus norvegicus
• Alignment Length: 401
• Identity: 97/401 - (24%)
• Similarity: 158/401 - (39%)
• Gaps: 138/401 - (34%)

  Fly   117 SYSMILLFAVLGNLLVISTLVQNRRMRTITNVFLLNLAISDMLLGVLCMPVTLVGTLLRNFIFGE 181
            :|..:::..|.|||.:|..:::.:.||.:||:.::||:.||:|:.|:|:|.|.|.||:.:::|||
  Rat    45 AYGAVIILGVSGNLALIIIILKQKEMRNVTNILIVNLSFSDLLVAVMCLPFTFVYTLMDHWVFGE 109

  Fly   182 FLCKLFQFSQAASVAVSSWTLVAISCERYYAICHPLRSRSWQTIS-HAYKIIGFIWLGGILCMTP 245
            .:|||..|.|..|:.||.::||.|:.||:..|.:|   |.|:..: |||..|..||:..:....|
  Rat   110 TMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINP---RGWRPNNRHAYIGITVIWVLAVASSLP 171

  Fly   246 IAVFSQLIPTSRP-----------GYCKCREFWPDQGYELFYNILLDFLLLVLPLLVLCVAYILI 299
            ..::.  |.|..|           .|. |.:.:|...:.|.|..||..|....||..:.:.|..|
  Rat   172 FVIYQ--ILTDEPFQNVSLAAFKDKYV-CFDKFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKI 233

  Fly   300 TRTLYVGMAKDSGRILQQSLPVSATTAGGSAPNPGTSSSSNCILVLTATAVYNENSNNNNGNSEG 364
                                                                             
  Rat   234 ----------------------------------------------------------------- 233

  Fly   365 SAGGGSTNMATTTLTTRPTAPTVITTTTTTTVTLAKTSSPSIRVHDAALRRSNEAKTLESKKRVV 429
                                          .|.|.:.::...::.|:..|.|       ..||:.
  Rat   234 ------------------------------YVRLKRRNNMMDKIRDSKYRSS-------ETKRIN 261

  Fly   430 KMLFVLVLEFFICWTPLYVINTMVMLIGPVVYEYVDYTAIS-------FL--QLLAYSSSCCNPI 485
            .||..:|:.|.:||.||.:.||        |::: ::..|:       ||  .|.|..|:|.|||
  Rat   262 VMLLSIVVAFAVCWLPLTIFNT--------VFDW-NHQIIATCNHNLLFLLCHLTAMISTCVNPI 317

  Fly   486 TYCFMNASFRR 496
            .|.|:|.:|:|
  Rat   318 FYGFLNKNFQR 328

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D3	NP_001097023.1	7tm_GPCRs	112..498	CDD:475119	97/401 (24%)
		TM helix 1	114..138	CDD:320334	6/20 (30%)
		TM helix 2	147..169	CDD:320334	9/21 (43%)
		TM helix 3	185..207	CDD:320334	10/21 (48%)
		TM helix 4	230..246	CDD:320334	3/15 (20%)
		TM helix 5	274..297	CDD:320334	7/22 (32%)
		TM helix 6	429..451	CDD:320334	8/21 (38%)
		TM helix 7	466..491	CDD:320334	12/33 (36%)
Npy1r	NP_001106828.1	7tmA_NPY1R	40..330	CDD:320517	97/401 (24%)
		TM helix 1	41..67	CDD:320517	6/21 (29%)
		TM helix 2	74..99	CDD:320517	11/24 (46%)
		TM helix 3	112..142	CDD:320517	13/29 (45%)
		TM helix 4	153..174	CDD:320517	7/20 (35%)
		TM helix 5	207..236	CDD:320517	9/123 (7%)
		TM helix 6	255..285	CDD:320517	13/44 (30%)
		TM helix 7	298..323	CDD:320517	11/24 (46%)