Protein Alignment CCKLR-17D3 and Qrfpr

DIOPT Version :10

• Sequence 1: NP_001097023.1
• Gene: CCKLR-17D3 / 32864
• FlyBaseID: FBgn0030954
• Length: 584
• Species: Drosophila melanogaster
• Sequence 2: NP_937835.1
• Gene: Qrfpr / 229214
• MGIID: 2677633
• Length: 433
• Species: Mus musculus
• Alignment Length: 459
• Identity: 112/459 - (24%)
• Similarity: 185/459 - (40%)
• Gaps: 134/459 - (29%)

  Fly   119 SMILLFAVLGNLLVISTLVQNRRMRTITNVFLLNLAISDMLLGVLCMPVTLVGTLLRNFIFGEFL 183
            ::|...|:.||.|||..:.:::.|||:||:|:.:||:||:|:...|:|||::..:...::.|.|:
Mouse    53 ALIFALALFGNSLVIYVVTRSKAMRTVTNIFICSLALSDLLIAFFCIPVTMLQNISDKWLGGAFI 117

  Fly   184 CKLFQFSQAASVAVSSWTLVAISCERYYAICHPLRSRSWQ-TISHAYKIIGFIWLGGILCMTPIA 247
            ||:..|.|:.:|.....|:..|:.||:..:.||.:.: || |...|:.|:|.:||..|:..:|:.
Mouse   118 CKMVPFVQSTAVVTEILTMTCIAVERHQGLIHPFKMK-WQYTTRRAFTILGVVWLAAIIVGSPMW 181

  Fly   248 VFSQL-----IPTSRPGYCKCREFWPDQGYELFYNILLDFLLLVLPLLVLCVAYILITRTLYVGM 307
            ...:|     ....:...| |.|.|....::..|...:..:|.:|||:|:.|.|..|...|::
Mouse   182 HVQRLEIKYDFLYEKEHVC-CLEEWASPMHQRIYTTFILVILFLLPLVVMLVLYSKIGYELWI-- 243

  Fly   308 AKDSGRILQQSLPVSATTAGGSAPNPGTSSSSNCILVLTATAVYNENSNNNNGNSEGSAGGGSTN 372
               ..|:                                                     |.|:.
Mouse   244 ---KKRV-----------------------------------------------------GDSSA 252

  Fly   373 MATTTLTTRPTAPTVITTTTTTTVTLAKTSSPSIRVHDAALRRSNEAKTLESKKRVVKMLFVLVL 437
            :.|                                :|...:     :|....|||.|.|:..:|.
Mouse   253 LQT--------------------------------IHGKEM-----SKIARKKKRAVVMMVTVVA 280

  Fly   438 EFFICWTPLYVINTMVMLIGPVVY-----EYVDYT---AISFLQLLAYSSSCCNPITYCFMNASF 494
            .|..||.|.:|::.|      |.|     ||.|.|   ..:..|.:.:.:|.|||..|.|||.:|
Mouse   281 LFAACWAPFHVVHMM------VEYSNFEKEYDDVTIKMVFAVAQTIGFFNSICNPFVYAFMNENF 339

  Fly   495 RRAFV---------DTFKGLPWRRGAGASGGVGGAAGGGLSASQ---AGAGPGAYASANTNISL- 546
            ::.|:         :||.  |.:: .|.||.........||.||   |.|....::.||.::.|
Mouse   340 KKNFLSAVCYCIVRETFS--PGQK-PGNSGISMMQKRAKLSRSQRPVAEAKGDLFSDANVDVKLC 401

  Fly   547 -NPG 549
             .||
Mouse   402 EQPG 405

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D3	NP_001097023.1	7tm_GPCRs	112..498	CDD:475119	94/392 (24%)
		TM helix 1	114..138	CDD:320334	7/18 (39%)
		TM helix 2	147..169	CDD:320334	10/21 (48%)
		TM helix 3	185..207	CDD:320334	6/21 (29%)
		TM helix 4	230..246	CDD:320334	5/15 (33%)
		TM helix 5	274..297	CDD:320334	7/22 (32%)
		TM helix 6	429..451	CDD:320334	8/21 (38%)
		TM helix 7	466..491	CDD:320334	8/27 (30%)
Qrfpr	NP_937835.1	7tmA_QRFPR	46..343	CDD:320333	94/392 (24%)
		TM helix 1	47..73	CDD:320333	7/19 (37%)
		TM helix 2	80..106	CDD:320333	12/25 (48%)
		TM helix 3	118..148	CDD:320333	9/29 (31%)
		TM helix 4	161..182	CDD:320333	7/20 (35%)
		TM helix 5	211..236	CDD:320333	8/24 (33%)
		TM helix 6	266..296	CDD:320333	12/35 (34%)
		TM helix 7	311..336	CDD:320333	7/24 (29%)