Protein Alignment CCKLR-17D3 and Sstr1

DIOPT Version :10

• Sequence 1: NP_001097023.1
• Gene: CCKLR-17D3 / 32864
• FlyBaseID: FBgn0030954
• Length: 584
• Species: Drosophila melanogaster
• Sequence 2: NP_033242.1
• Gene: Sstr1 / 20605
• MGIID: 98327
• Length: 391
• Species: Mus musculus
• Alignment Length: 451
• Identity: 107/451 - (23%)
• Similarity: 179/451 - (39%)
• Gaps: 156/451 - (34%)

  Fly    86 FSLGTSSSPSPSSTPASSS-------------------------------STSTGMPVWLIPSYS 119
            |..||:||||.|.:|:..|                               |...|..:.:...||
Mouse     2 FPNGTASSPSSSPSPSPGSCGEGACSRGPGSGAADGMEEPGRNASQNGTLSEGQGSAILISFIYS 66

  Fly   120 MILLFAVLGNLLVISTLVQNRRMRTITNVFLLNLAISDMLLGVLCMPVTLVGTLLRNFIFGEFLC 184
            ::.|..:.||.:||..:::..:|:|.||:::|||||:|.|| :|.:|..:..||||::.||..||
Mouse    67 VVCLVGLCGNSMVIYVILRYAKMKTATNIYILNLAIADELL-MLSVPFLVTSTLLRHWPFGALLC 130

  Fly   185 KLFQFSQAASVAVSSWTLVAISCERYYAICHPLRSRSWQTISHAYKIIGF-IWLGGILCMTPIAV 248
            :|.....|.::..|.:.|..:|.:||.|:.||:::..::..:.| |::.. :|:..:|.:.||.|
Mouse   131 RLVLSVDAVNMFTSIYCLTVLSVDRYVAVVHPIKAARYRRPTVA-KVVNLGVWVLSLLVILPIVV 194

  Fly   249 FSQLIPTSRPGYCKCREFWPDQ------GYELFYNILLDFLLLVLPLLVLCVAYILITRTLYVGM 307
            ||:....| .|...|....|:.      |:.| |..|:.||   ||:..:|:.|:||
Mouse   195 FSRTAANS-DGTVACNMLMPEPAQRWLVGFVL-YTFLMGFL---LPVGAICLCYVLI-------- 246

  Fly   308 AKDSGRILQQSLPVSATTAGGSAPNPGTSSSSNCILVLTATAVYNENSNNNNGNSEGSAGGGSTN 372
                                                                             
Mouse   247 ----------------------------------------------------------------- 246

  Fly   373 MATTTLTTRPTAPTVITTTTTTTVTLAKTSSPSIRVHDAALRRSNEAKTLESKKRVVKMLFVLVL 437
                                     :||....:::......:|        |::::..|:.::|:
Mouse   247 -------------------------IAKMRMVALKAGWQQRKR--------SERKITLMVMMVVM 278

  Fly   438 EFFICWTPLYVINTMVMLIGPVVYEYVDYTAISFLQLLAYSSSCCNPITYCFMNASFRRAF 498
            .|.|||.|.||    |.|:. |..|..|.|......:|.|::||.|||.|.|::.:|:|:|
Mouse   279 VFVICWMPFYV----VQLVN-VFAEQDDATVSQLSVILGYANSCANPILYGFLSDNFKRSF 334

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D3	NP_001097023.1	7tm_GPCRs	112..498	CDD:475119	94/392 (24%)
		TM helix 1	114..138	CDD:320334	7/23 (30%)
		TM helix 2	147..169	CDD:320334	11/21 (52%)
		TM helix 3	185..207	CDD:320334	4/21 (19%)
		TM helix 4	230..246	CDD:320334	3/16 (19%)
		TM helix 5	274..297	CDD:320334	8/22 (36%)
		TM helix 6	429..451	CDD:320334	9/21 (43%)
		TM helix 7	466..491	CDD:320334	10/24 (42%)
Sstr1	NP_033242.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..50		10/47 (21%)
		7tmA_SSTR1	59..334	CDD:320636	94/392 (24%)
		TM helix 1	60..86	CDD:320636	7/25 (28%)
		TM helix 2	93..119	CDD:320636	12/26 (46%)
		TM helix 3	130..160	CDD:320636	9/29 (31%)
		TM helix 4	172..194	CDD:320636	6/22 (27%)
		TM helix 5	220..249	CDD:320636	12/130 (9%)
		TM helix 6	264..294	CDD:320636	13/41 (32%)
		TM helix 7	302..327	CDD:320636	10/24 (42%)