Protein Alignment CCKLR-17D3 and Npy4r

DIOPT Version :10

• Sequence 1: NP_001097023.1
• Gene: CCKLR-17D3 / 32864
• FlyBaseID: FBgn0030954
• Length: 584
• Species: Drosophila melanogaster
• Sequence 2: NP_032945.3
• Gene: Npy4r / 19065
• MGIID: 105374
• Length: 375
• Species: Mus musculus
• Alignment Length: 424
• Identity: 97/424 - (22%)
• Similarity: 148/424 - (34%)
• Gaps: 120/424 - (28%)

  Fly    87 SLGTSSSPSPSSTPASSS---STSTGMPVWLIPSYSMILLFAVLGNLLVISTLVQNRRMRTITNV 148
            ||...:..:|..:|.:.|   ..|..:..::|.:||:..:..|||||.:|....:.:....:||:
Mouse    14 SLQGKNGTNPLDSPYNFSDGCQDSAELLAFIITTYSIETILGVLGNLCLIFVTTRQKEKSNVTNL 78

  Fly   149 FLLNLAISDMLLGVLCMPVTLVGTLLRNFIFGEFLCKLFQFSQAASVAVSSWTLVAISCERYYAI 213
            .:.|||.||.|:.::|.|:|:..|::..:||||.|||:..|.|..||.||..:||.::.||:..|
Mouse    79 LIANLAFSDFLMCLICQPLTVTYTIMDYWIFGEVLCKMLTFIQCMSVTVSILSLVLVALERHQLI 143

  Fly   214 CHPLRSRSWQ-TISHAYKIIGFIWLGGILCMTPIAVFSQLIPTSRPGYCKCREF----------W 267
            .:|   ..|: :|..||..|..||........|....|.|.......:.|..||          |
Mouse   144 INP---TGWKPSIFQAYLGIVVIWFVSCFLSLPFLANSTLNDLFHYNHSKVVEFLEDKVVCFVSW 205

  Fly   268 PDQGYELFYNILLDFLLLVLPLLVLCVAYILITRTLYVGMAKDSGRILQQSLPVSATTAGGSAPN 332
            ....:.|.|...|......:||..:.|.||.|.:.            ||:...|
Mouse   206 SSDHHRLIYTTFLLLFQYCIPLAFILVCYIRIYQR------------LQRQKHV----------- 247

  Fly   333 PGTSSSSNCILVLTATAVYNENSNNNNGNSEGSAGGGSTNMATTTLTTRPTAPTVITTTTTTTVT 397
                                                                             
Mouse   248 ----------------------------------------------------------------- 247

  Fly   398 LAKTSSPSIRVHDAALRRSNEAKTLESKKRVVKMLFVLVLEFFICWTPLYVINTMVMLIGPVVYE 462
                    ...|..:.|..       ..||:..||..:|..|.:.|.||:|.||:.......:..
Mouse   248 --------FHAHACSSRAG-------QMKRINSMLMTMVTAFAVLWLPLHVFNTLEDWYQEAIPA 297

  Fly   463 YVDYTAISFLQLLAYSSSCCNPITYCFMNASFRR 496
            ...........|||.:|:|.||..|.|:|.:|::
Mouse   298 CHGNLIFLMCHLLAMASTCVNPFIYGFLNINFKK 331

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D3	NP_001097023.1	7tm_GPCRs	112..498	CDD:475119	91/396 (23%)
		TM helix 1	114..138	CDD:320334	9/23 (39%)
		TM helix 2	147..169	CDD:320334	9/21 (43%)
		TM helix 3	185..207	CDD:320334	9/21 (43%)
		TM helix 4	230..246	CDD:320334	3/15 (20%)
		TM helix 5	274..297	CDD:320334	6/22 (27%)
		TM helix 6	429..451	CDD:320334	8/21 (38%)
		TM helix 7	466..491	CDD:320334	9/24 (38%)
Npy4r	NP_032945.3	7tmA_NPY4R	43..333	CDD:320519	91/395 (23%)
		TM helix 1	43..69	CDD:320519	9/25 (36%)
		TM helix 2	76..101	CDD:320519	11/24 (46%)
		TM helix 3	114..144	CDD:320519	12/29 (41%)
		TM helix 4	155..176	CDD:320519	6/20 (30%)
		TM helix 5	211..240	CDD:320519	9/28 (32%)
		TM helix 6	258..288	CDD:320519	12/36 (33%)
		TM helix 7	301..326	CDD:320519	9/24 (38%)