Protein Alignment CCKLR-17D3 and npr-7

DIOPT Version :10

• Sequence 1: NP_001097023.1
• Gene: CCKLR-17D3 / 32864
• FlyBaseID: FBgn0030954
• Length: 584
• Species: Drosophila melanogaster
• Sequence 2: NP_509570.3
• Gene: npr-7 / 185321
• WormBaseID: WBGene00018067
• Length: 380
• Species: Caenorhabditis elegans
• Alignment Length: 414
• Identity: 88/414 - (21%)
• Similarity: 152/414 - (36%)
• Gaps: 119/414 - (28%)

  Fly   110 MPVWLIPSYSMILLFAVLGNLLVISTLVQNRRMRTITNVFLLNLAISDMLLGVLCMPVTLVGTLL 174
            |...|...|.::...:::|||.|:..::..|.|:|:||:|:.:::.:|:::....:..|.:....
 Worm    23 MKTLLAVGYGLVGALSLVGNLAVLLIVICRREMQTVTNIFISSVSAADLVITSFSLWATPLAYYQ 87

  Fly   175 RNFIFGEFLCKLFQFSQAASVAVSSWTLVAISCERYYAICHPLRSRSWQTISH--AYKIIGFIWL 237
            |.:.||:::|.:....|..|:.....||.|::.:||..:..|.|    |.:|.  ...||..||:
 Worm    88 RVWHFGKYMCYMVSIIQGLSLMWVPLTLAAVALDRYSLVASPFR----QPMSKKTCLLIIAGIWM 148

  Fly   238 GGILCMTPIAVFSQLIPTSRPGYCK-CREFW--PDQGYELFYNILLDFLLLVLPLLVLCVAYILI 299
            ||...::|:......:.:..|  |. |.|.|  ..|.|.|||.:.:..:...:||:::.:.:..|
 Worm   149 GGFAVLSPMIRMVDFVDSYGP--CHFCLESWDHDKQHYRLFYGLSVLVIRSAIPLVLISLCHWRI 211

  Fly   300 TRTLYVGMAKDSGRILQQSLPVSATTAGGSAPNPGTSSSSNCILVLTATAVYNENSNNNNGNSEG 364
            ...|
 Worm   212 AVIL------------------------------------------------------------- 215

  Fly   365 SAGGGSTNMATTTLTTRPTAPTVITTTTTTTVTLAKTSSPSIRVHDAALRRSNEAKTLESKKRVV 429
                   |..|....|..:|.||             |.|..||                .|:|:.
 Worm   216 -------NTQTKKFQTLRSASTV-------------TQSTDIR----------------RKQRLQ 244

  Fly   430 KMLFVLVLEFFICWTPLYVINTMVMLIGPVVYEY------VDYTAISFLQLLAYSSSCCNPITYC 488
            .:|..:|:.|.:...||.:.|.:..||  |||:.      |.:....|....|.:.:..||:.|.
 Worm   245 TLLLAMVVIFAVSSLPLDLSNVLQDLI--VVYQVRPVPDNVRHFIFFFCHWTAMAGTLLNPLVYA 307

  Fly   489 FMNASFRRAFVDTFKGLPWRRGAG 512
            :.|.:|||.....|..:   ||.|
 Worm   308 YYNENFRRQIQTCFGEM---RGQG 328

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D3	NP_001097023.1	7tm_GPCRs	112..498	CDD:475119	83/396 (21%)
		TM helix 1	114..138	CDD:320334	6/23 (26%)
		TM helix 2	147..169	CDD:320334	3/21 (14%)
		TM helix 3	185..207	CDD:320334	5/21 (24%)
		TM helix 4	230..246	CDD:320334	6/15 (40%)
		TM helix 5	274..297	CDD:320334	5/22 (23%)
		TM helix 6	429..451	CDD:320334	5/21 (24%)
		TM helix 7	466..491	CDD:320334	5/24 (21%)
npr-7	NP_509570.3	7tmA_NPYR-like	25..317	CDD:320331	83/396 (21%)
		TM helix 1	26..52	CDD:320331	6/25 (24%)
		TM helix 2	59..84	CDD:320331	5/24 (21%)
		TM helix 3	97..127	CDD:320331	8/29 (28%)
		TM helix 4	138..159	CDD:320331	7/20 (35%)
		TM helix 5	185..214	CDD:320331	6/28 (21%)
		TM helix 6	238..268	CDD:320331	9/45 (20%)
		TM helix 7	285..310	CDD:320331	5/24 (21%)