Protein Alignment CCKLR-17D3 and npr-35

DIOPT Version :10

• Sequence 1: NP_001097023.1
• Gene: CCKLR-17D3 / 32864
• FlyBaseID: FBgn0030954
• Length: 584
• Species: Drosophila melanogaster
• Sequence 2: NP_001023088.2
• Gene: npr-35 / 183681
• WormBaseID: WBGene00016842
• Length: 384
• Species: Caenorhabditis elegans
• Alignment Length: 406
• Identity: 86/406 - (21%)
• Similarity: 147/406 - (36%)
• Gaps: 150/406 - (36%)

  Fly   117 SYSMILLFAVLGNLLVISTLVQNRRMRTITNVFLLNLAISDMLLGVLCMPVTLVGTLLRNFIFGE 181
            :|..:....||||..|:..:..::.:...|:..:|:||::|:.:..:|:|.||:.::...:::|:
 Worm    38 AYGAVFFTGVLGNTFVVLAVWAHKNLNITTDYLILSLALADLFILWICLPTTLINSIFTEWLWGQ 102

  Fly   182 FLCKLFQFSQAASVAVSSWTLVAISCERYYAICHPLR-SRSWQTISHAYKIIGFIWLGGILCMTP 245
            |.|:|..::.|::...|.:||||::.:||.||||.|: :.||......| :|..:||...:...|
 Worm   103 FFCRLSTWANASTSFASVYTLVAVTADRYLAICHTLKYNTSWDREYTKY-VIFAVWLVAAIFGIP 166

  Fly   246 ------IAVFSQLIPTSRPGYCKCREFWPDQGYELFYNILLDFLLLVLPLLVLCVAY--ILITRT 302
                  :.|:.:    ...||..|......:.|.||.|:||.|   ::|..::...|  |.||.:
 Worm   167 NWYNYDLIVWQE----GSYGYRLCTSQTDQKLYFLFVNLLLAF---IVPFGLISGLYTRIFITVS 224

  Fly   303 LYVGMAKDSGRILQQSLPVSATTAGGSAPNPGTSSSSNCILVLTATAVYNENSNNNNGNSEGSAG 367
            .:..:|.|:
 Worm   225 THRSLAVDA-------------------------------------------------------- 233

  Fly   368 GGSTNMATTTLTTRPTAPTVITTTTTTTVTLAKTSSPSIRVHDAALRRSNEAKTLESKKRVVKML 432
                                                           |:.|.:.   |.||..|:
 Worm   234 -----------------------------------------------RAREDRV---KLRVATMM 248

  Fly   433 FVLVLEFFICWTPLYVINTMV---------------MLIGPVVYEYVDYTAISFLQLLAYSSSCC 482
            ..:::.|..||.|||.|.|..               |||.|:            .|.::..||..
 Worm   249 LTVIIVFACCWLPLYCIFTYFFFFADQRSDLFQITSMLIRPI------------FQWMSLLSSSL 301

  Fly   483 NPITYCFMNASFRRAF 498
            |||.|...:..:||||
 Worm   302 NPIIYIAYSHKYRRAF 317

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D3	NP_001097023.1	7tm_GPCRs	112..498	CDD:475119	84/404 (21%)
		TM helix 1	114..138	CDD:320334	6/20 (30%)
		TM helix 2	147..169	CDD:320334	6/21 (29%)
		TM helix 3	185..207	CDD:320334	7/21 (33%)
		TM helix 4	230..246	CDD:320334	4/21 (19%)
		TM helix 5	274..297	CDD:320334	8/24 (33%)
		TM helix 6	429..451	CDD:320334	8/21 (38%)
		TM helix 7	466..491	CDD:320334	7/24 (29%)
npr-35	NP_001023088.2	7tm_GPCRs	33..317	CDD:475119	84/404 (21%)
		TM helix 1	35..59	CDD:410628	6/20 (30%)
		TM helix 2	68..90	CDD:410628	6/21 (29%)
		TM helix 3	106..128	CDD:410628	7/21 (33%)
		TM helix 4	151..167	CDD:410628	4/16 (25%)
		TM helix 5	194..217	CDD:410628	8/25 (32%)
		TM helix 6	245..267	CDD:410628	8/21 (38%)
		TM helix 7	285..310	CDD:410628	11/36 (31%)