Protein Alignment CCKLR-17D3 and npr-11

DIOPT Version :10

• Sequence 1: NP_001097023.1
• Gene: CCKLR-17D3 / 32864
• FlyBaseID: FBgn0030954
• Length: 584
• Species: Drosophila melanogaster
• Sequence 2: NP_508234.2
• Gene: npr-11 / 182921
• WormBaseID: WBGene00016110
• Length: 402
• Species: Caenorhabditis elegans
• Alignment Length: 401
• Identity: 93/401 - (23%)
• Similarity: 150/401 - (37%)
• Gaps: 120/401 - (29%)

  Fly   117 SYSMILLFAVLGNLLVISTLVQNRRMRTITNVFLLNLAISDMLLGVLCMPVTLVGTLLRNFIFGE 181
            :|.:|:||..:||.|.|..::.|..|||..|.|:||||:||..:.::..|.||...|...:.|..
 Worm    45 AYMLIILFGAIGNFLTIIVVILNPAMRTTRNFFILNLALSDFFVCIVTAPTTLYTVLYMFWPFSR 109

  Fly   182 FLCKLFQFSQAASVAVSSWTLVAISCERYYAICHPLRSRSWQTISHAYKIIGFIWLGGILCMTPI 246
            .|||:....|..::.:|::::.:|:.:||..|..|.:....|.:|..:.|:  ||:..::...|:
 Worm   110 TLCKIAGSLQGFNIFLSTFSIASIAVDRYVLIIFPTKRERQQNLSFCFFIM--IWVISLILAVPL 172

  Fly   247 AVFSQLIPTSRPGYCKCREFWPDQGYELFYNILLD---FLLLVL------PLLVLCVAYILITRT 302
            ...|.|.|......|....:...:..|::..:::.   :.|.||      ||..|..||..|...
 Worm   173 LQASDLTPVFVEPSCDLALYICHEQNEIWEKMIISKGTYTLAVLITQYAFPLFSLVFAYSRIAHR 237

  Fly   303 LYVGMAKDSGRILQQSLPVSATTAGGSAPNPGTSSSSNCILVLTATAVYNENSNNNNGNSEGSAG 367
            :.:..|                                           |.|.|
 Worm   238 MKLRFA-------------------------------------------NRNQN----------- 248

  Fly   368 GGSTNMATTTLTTRPTAPTVITTTTTTTVTLAKTSSPSIRVHDAALRRSNEAKTLESKKRVVKML 432
                                :||.|.|                :..|||    .:|.::|...:|
 Worm   249 --------------------VTTNTNT----------------SQRRRS----VVERQRRTHLLL 273

  Fly   433 FVLVLEFFICWTPL---YVINTMVMLIGPVVYEYVD---YTAISFLQLLAYSSSCCNPITYCFMN 491
            ..:|..|.:.|.||   ::.||         :|.|:   .|..|....||..|:|.||:.|.|.|
 Worm   274 VCVVAVFAVAWLPLNVFHIFNT---------FELVNSFSVTTFSICHCLAMCSACLNPLIYAFFN 329

  Fly   492 ASFRRAFVDTF 502
            .:||..|:..|
 Worm   330 HNFRIEFMHLF 340

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D3	NP_001097023.1	7tm_GPCRs	112..498	CDD:475119	91/395 (23%)
		TM helix 1	114..138	CDD:320334	8/20 (40%)
		TM helix 2	147..169	CDD:320334	9/21 (43%)
		TM helix 3	185..207	CDD:320334	4/21 (19%)
		TM helix 4	230..246	CDD:320334	3/15 (20%)
		TM helix 5	274..297	CDD:320334	7/31 (23%)
		TM helix 6	429..451	CDD:320334	6/24 (25%)
		TM helix 7	466..491	CDD:320334	10/24 (42%)
npr-11	NP_508234.2	7tmA_NPYR-like	40..336	CDD:320331	91/395 (23%)
		TM helix 1	41..67	CDD:320331	8/21 (38%)
		TM helix 2	74..99	CDD:320331	11/24 (46%)
		TM helix 3	112..142	CDD:320331	7/29 (24%)
		TM helix 4	153..174	CDD:320331	5/22 (23%)
		TM helix 5	208..237	CDD:320331	9/28 (32%)
		TM helix 6	264..294	CDD:320331	8/29 (28%)
		TM helix 7	304..329	CDD:320331	10/24 (42%)