Protein Alignment CCKLR-17D3 and Npy6r

DIOPT Version :10

• Sequence 1: NP_001097023.1
• Gene: CCKLR-17D3 / 32864
• FlyBaseID: FBgn0030954
• Length: 584
• Species: Drosophila melanogaster
• Sequence 2: NP_035065.1
• Gene: Npy6r / 18169
• MGIID: 1098590
• Length: 371
• Species: Mus musculus
• Alignment Length: 438
• Identity: 101/438 - (23%)
• Similarity: 177/438 - (40%)
• Gaps: 147/438 - (33%)

  Fly    91 SSSPSPSSTPASSSST------STGMP----VWLIPSYSMILLFAVLGNL-LVISTLVQNRRMRT 144
            ::.|:|:.|...|:::      |...|    :.|:.:|::||:..:.||| |:|....:.|..:.
Mouse     5 TNQPTPNKTSGKSNNSAFFYFESCQPPFLAILLLLIAYTVILIMGIFGNLSLIIIIFKKQREAQN 69

  Fly   145 ITNVFLLNLAISDMLLGVLCMPVTLVGTLLRNFIFGEFLCKLFQFSQAASVAVSSWTLVAISCER 209
            :||:.:.||::||:|:.|:|:|.|::.||:.:::||..:|||..:.|:.||:||.::||.|:.||
Mouse    70 VTNILIANLSLSDILVCVMCIPFTVIYTLMDHWVFGNTMCKLTSYVQSVSVSVSIFSLVLIAIER 134

  Fly   210 YYAICHPLRSRSWQ-TISHAYKIIGFIWLGGILCMTPIAVFSQLIPTSRPGY------------C 261
            |..|.:|   |.|: .::|||..|..|||..:....|:.:...|  |:.|.:            .
Mouse   135 YQLIVNP---RGWKPRVAHAYWGIILIWLISLTLSIPLFLSYHL--TNEPFHNLSLPTDIYTHQV 194

  Fly   262 KCREFWPDQGYELFYNILLDFLLLVLPLLVLCVAYILITRTLYVGMAKDSGRILQQSLPVSATTA 326
            .|.|.||.:..:|.::..|..|...:||..:.:.|:.|
Mouse   195 ACVEIWPSKLNQLLFSTSLFMLQYFVPLGFILICYLKI--------------------------- 232

  Fly   327 GGSAPNPGTSSSSNCILVLTATAVYNENSNNNNGNSEGSAGGGSTNMATTTLTTRPTAPTVITTT 391
                                                                             
Mouse   233 ----------------------------------------------------------------- 232

  Fly   392 TTTTVTLAKTSSPSIRVHDAALRRSNEAKTLESKKRVVKMLFVLVLEFFICWTPLYVINTMVMLI 456
               .:.|.|      |......|:.|::: |...|||..||..:|:.|..||.||.:.|
Mouse   233 ---VLCLRK------RTRQVDRRKENKSR-LNENKRVNVMLISIVVTFGACWLPLNIFN------ 281

  Fly   457 GPVVYEYVDYTAIS--------FLQLLAYSSSCCNPITYCFMNASFRR 496
              |::::.....:|        ...|:|..|:|.||:.|.|:|.:|::
Mouse   282 --VIFDWYHEMLMSCHHDLVFVVCHLIAMVSTCINPLFYGFLNKNFQK 327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D3	NP_001097023.1	7tm_GPCRs	112..498	CDD:475119	95/407 (23%)
		TM helix 1	114..138	CDD:320334	9/24 (38%)
		TM helix 2	147..169	CDD:320334	9/21 (43%)
		TM helix 3	185..207	CDD:320334	10/21 (48%)
		TM helix 4	230..246	CDD:320334	4/15 (27%)
		TM helix 5	274..297	CDD:320334	5/22 (23%)
		TM helix 6	429..451	CDD:320334	8/21 (38%)
		TM helix 7	466..491	CDD:320334	9/32 (28%)
Npy6r	NP_035065.1	7tm_GPCRs	42..329	CDD:475119	94/401 (23%)
		TM helix 1	42..63	CDD:320518	8/20 (40%)
		TM helix 2	72..94	CDD:320518	9/21 (43%)
		TM helix 3	110..132	CDD:320518	10/21 (48%)
		TM helix 4	153..169	CDD:320518	4/15 (27%)
		TM helix 5	207..230	CDD:320518	5/22 (23%)
		TM helix 6	260..282	CDD:320518	9/29 (31%)
		TM helix 7	297..322	CDD:320518	8/24 (33%)