Protein Alignment CCKLR-17D3 and sNPF-R

DIOPT Version :10

• Sequence 1: NP_001097023.1
• Gene: CCKLR-17D3 / 32864
• FlyBaseID: FBgn0030954
• Length: 584
• Species: Drosophila melanogaster
• Sequence 2: XP_320180.2
• Gene: sNPF-R / 1280335
• VectorBaseID: AGAMI1_013226
• Length: 575
• Species: Anopheles gambiae
• Alignment Length: 523
• Identity: 129/523 - (24%)
• Similarity: 198/523 - (37%)
• Gaps: 163/523 - (31%)

  Fly    52 GTVSLAGNATSSYGDDDRDGYMDTEPSDLV------TELAFSLGT----SSSPSPSSTPASSSST 106
            |.|||.|..|.:..       ..|.|:.:.      |||..: ||    :..|:....|:::::.
Mosquito     7 GLVSLVGAVTVATA-------TSTSPAAMASLVLDHTELPLA-GTIPPAALMPARVLLPSNATNL 63

  Fly   107 STGMPVWLIPS---------------------------YSMILLFAVLGNLLVISTLVQNRRMRT 144
            :..:...|.|:                           ||.|.:..|.||:||...:.:|:.|:|
Mosquito    64 TLTLEELLRPNSSTVAPPNGDNDIIFSNKLVQIVFCVLYSSIFVLGVFGNVLVCYVVFRNKAMQT 128

  Fly   145 ITNVFLLNLAISDMLLGVLCMPVTLVGTLLRNFIFGEFLCKLFQFSQAASVAVSSWTLVAISCER 209
            :||:|:.|||:||:||.||.:|.|...|.:|.::||:.||.....:|..||.:|:.||.:|:.:|
Mosquito   129 VTNLFITNLALSDILLCVLAVPFTPSYTFMRRWVFGKLLCHTVPLAQGCSVYISTLTLTSIAIDR 193

  Fly   210 YYAICHPLRSRSWQTISHAYKIIGFIWLGGILCMTPIAVFSQLI------------PTSRPGYCK 262
            ::.|.:|...|  ..:|....||..||...|:...|..::.:|.            |.|...||:
Mosquito   194 FFVIIYPFHPR--MKLSTCITIIVLIWSFAIMVTMPYGLYMKLHGVALNGTDNATGPLSSAMYCE 256

  Fly   263 CREFWPDQGYELFYNILLDFLLLVLPLLVLCVAYILITRTLYVGMAKDSGRILQQSLPVSATTAG 327
              |.||.:.....::|:...|..|||.:::...||.::..|
Mosquito   257 --ELWPSEEMRKTFSIVTSILQFVLPFIIMAFCYICVSIRL------------------------ 295

  Fly   328 GSAPNPGTSSSSNCILVLTATAVYNENSNNNNGNSEGSAGGGSTNMATTTLTTRPTAPTVITTTT 392
                                    |:.:....|
Mosquito   296 ------------------------NDRARTKPG-------------------------------- 304

  Fly   393 TTTVTLAKTSSPSIRVHDAALRRSNEAKTLESKKRVVKMLFVLVLEFFICWTPLYVINTMVMLIG 457
                  :|||            |..||.. :.|||..:||..:|..|.|.|.||.|:| |.....
Mosquito   305 ------SKTS------------RREEADR-DRKKRTNRMLISMVAIFGISWLPLNVVN-MCNDFN 349

  Fly   458 PVVYEYVDYTAISFL-QLLAYSSSCCNPITYCFMNASFRRAFVDTFKGL-PWRRGAGASGGVGGA 520
            ..:..:..|..|.|: .|.|.||:|.||..|.::|.:||:.|....... |.|..||..||..||
Mosquito   350 SDINSWRFYNLIFFIAHLTAMSSTCYNPFLYAWLNDNFRKEFKQVLPCFDPSRGRAGTVGGNRGA 414

  Fly   521 AGG 523
            .||
Mosquito   415 GGG 417

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D3	NP_001097023.1	7tm_GPCRs	112..498	CDD:475119	103/425 (24%)
		TM helix 1	114..138	CDD:320334	10/50 (20%)
		TM helix 2	147..169	CDD:320334	12/21 (57%)
		TM helix 3	185..207	CDD:320334	7/21 (33%)
		TM helix 4	230..246	CDD:320334	5/15 (33%)
		TM helix 5	274..297	CDD:320334	5/22 (23%)
		TM helix 6	429..451	CDD:320334	9/21 (43%)
		TM helix 7	466..491	CDD:320334	11/25 (44%)
sNPF-R	XP_320180.2	None