Protein Alignment CCKLR-17D3 and LOC1271906

DIOPT Version :10

• Sequence 1: NP_001097023.1
• Gene: CCKLR-17D3 / 32864
• FlyBaseID: FBgn0030954
• Length: 584
• Species: Drosophila melanogaster
• Sequence 2: XP_061514608.1
• Gene: LOC1271906 / 1271906
• VectorBaseID: AGAMI1_012393
• Length: 567
• Species: Anopheles gambiae
• Alignment Length: 531
• Identity: 151/531 - (28%)
• Similarity: 222/531 - (41%)
• Gaps: 160/531 - (30%)

  Fly    25 DYYANA---PSAA--GHIVSLNVAPYNGTGNGGTVSLAGNATSSYGDDDRDGYMD---------- 74
            ||:|.|   .|||  |.:.|...|. ||||:||..:|||:..||.|........|
Mosquito    10 DYFARAMRNESAAPGGGVYSTGPAG-NGTGSGGFGALAGSNASSAGSAAGPELFDMYARNYPYVS 73

  Fly    75 -TEPSDLVTELAFSL-------------------------GTSSSPSPSSTPASSSSTSTGMPVW 113
             ||..:.:.:|:.||                         |....|.|.   |..|:..:..|.:
Mosquito    74 STEEQNYIEQLSDSLRNQSQAGNRSYGGAGGVGGAGGYDYGVGFDPIPL---AECSNAYSAGPYF 135

  Fly   114 LIPSYSM---ILLFAVLGNLLVISTLVQNRRMRTITNVFLLNLAISDMLLGVLCMPVTLVGT-LL 174
            .:.||.:   |.:.||:||.:|:..:..|.||||:||.|:.|||:.|:::.:.|:|.|.:.. :|
Mosquito   136 QLTSYFLYITIFVTAVIGNSIVLFIVQSNPRMRTVTNFFITNLAVGDLMMTLFCVPFTFISLFVL 200

  Fly   175 RNFIFGEFLCKLFQFSQAASVAVSSWTLVAISCERYYAICHPLRSRSWQTISHAYKIIGFIWLGG 239
            :.:.||..:|:|..::||.||.||::||||||.:||.||..|||.|..:|.|..  :||.:|:..
Mosquito   201 QYWPFGLAMCRLVNYTQAVSVLVSAYTLVAISGDRYIAIMWPLRPRITKTCSKC--LIGIVWIIA 263

  Fly   240 ILCMTPIAVFSQL-IPTSRPGYCK---CREFWPDQGYELFYNILLDFLLLVLPLLVLCVAYILIT 300
            ::...|||:||.| .||.....|.   |.|.||....:.:|.|.|.....::||:||...|..|
Mosquito   264 LITAVPIAIFSTLYFPTDWHVQCNVPICAEKWPSPEQDDYYTIALLTTQFIVPLVVLIFTYTRI- 327

  Fly   301 RTLYVGMAKDSGRILQQSLPVSATTAGGSAPNPGTSSSSNCILVLTATAVYNENSNNNNGNSEGS 365
                                  |....|..| ||.:                |||.:..
Mosquito   328 ----------------------AIVVWGKRP-PGEA----------------ENSRDQR------ 347

  Fly   366 AGGGSTNMATTTLTTRPTAPTVITTTTTTTVTLAKTSSPSIRVHDAALRRSNEAKTLESKKRVVK 430
                                            :||                       ||::::|
Mosquito   348 --------------------------------MAK-----------------------SKRKMIK 357

  Fly   431 MLFVLVLEFFICWTPLYVINTMVMLIGPVVYEYVDYTAISFLQLLAYSSSCCNPITYCFMNASFR 495
            |:..:|:.|.|||.|   .|.::::..|..::.:.|...:| ..||.|.||.|||.||:|||.||
Mosquito   358 MMVTVVIVFTICWLP---FNFLMLMKLPSSWDLLPYFWFAF-HWLAMSHSCYNPIIYCYMNARFR 418

  Fly   496 RAFVDTFKGLP 506
            ..|:....|:|
Mosquito   419 SGFILVLHGVP 429

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D3	NP_001097023.1	7tm_GPCRs	112..498	CDD:475119	114/393 (29%)
		TM helix 1	114..138	CDD:320334	8/26 (31%)
		TM helix 2	147..169	CDD:320334	8/21 (38%)
		TM helix 3	185..207	CDD:320334	12/21 (57%)
		TM helix 4	230..246	CDD:320334	3/15 (20%)
		TM helix 5	274..297	CDD:320334	7/22 (32%)
		TM helix 6	429..451	CDD:320334	8/21 (38%)
		TM helix 7	466..491	CDD:320334	12/24 (50%)
LOC1271906	XP_061514608.1	None