Protein Alignment CCKLR-17D3 and LOC1270512

DIOPT Version :10

• Sequence 1: NP_001097023.1
• Gene: CCKLR-17D3 / 32864
• FlyBaseID: FBgn0030954
• Length: 584
• Species: Drosophila melanogaster
• Sequence 2: XP_061518622.1
• Gene: LOC1270512 / 1270512
• VectorBaseID: AGAMI1_007575
• Length: 805
• Species: Anopheles gambiae
• Alignment Length: 736
• Identity: 231/736 - (31%)
• Similarity: 310/736 - (42%)
• Gaps: 240/736 - (32%)

  Fly    26 YYANAPSAAGHIVSLNV-APYNGTGNGGTVSLAGNATSSYGDDDRDGYMDTEPSDLVTELAFSLG 89
            |..|...|.|.::..|: |...||.|     |:||..|:.|:                 |..:.|
Mosquito    88 YGTNLSLALGELLRDNISATVVGTHN-----LSGNGRSAAGN-----------------LPPATG 130

  Fly    90 TSSSPSPSSTPASSSSTSTGMPVWLIPSYSMILLFAVLGNLLVISTLVQNRRMRTITNVFLLNLA 154
            |       .|..|.....|.....:||.|::|.|.:|:||||||.||.||:||||:|||:|||||
Mosquito   131 T-------GTAGSRGGDGTFQNQLIIPLYAIIFLLSVVGNLLVILTLAQNKRMRTVTNVYLLNLA 188

  Fly   155 ISDMLLGVLCMPVTLVGTLLRNFIFGEFLCKLFQFSQAASVAVSSWTLVAISCERYYAICHPLRS 219
            |||:||||.|||.||.|.:||.|:||..:|||..:.||.||:|:.|||||||.|||:|||.||.|
Mosquito   189 ISDLLLGVFCMPFTLAGQVLRRFVFGSVMCKLIPYFQAVSVSVAVWTLVAISLERYFAICRPLSS 253

  Fly   220 RSWQTISHAYKIIGFIWLGGILCMTPIAVFSQLIPTSR-PGYCKCREFWPDQGYELFYNILLDFL 283
            |.|||..||||:||.:|....|..:|:....:|:|..| .|..||||.||...:|..|.:..|..
Mosquito   254 RRWQTQFHAYKMIGLVWTVSFLANSPLGYVQRLLPVGRSTGQMKCREEWPSPAWERAYVLFHDVG 318

  Fly   284 LLVLPLLVLCVAYILITRTLYVGM---AKDSGRILQ---------QSLPVSATTAGGSAPNPGT- 335
            ||.||||.:..||.:|...|:.|:   .|.|....|         |...|.....|.:|.:.||
Mosquito   319 LLFLPLLTMGFAYSMIVSKLWRGLRHEIKHSSLYQQTSRQHGTGGQGSSVGGAPTGAAAGSVGTV 383

  Fly   336 SSSSNCI------------------LVLT----------ATAVYNENSNNN-------------- 358
            |...:|.                  .|||          :|||.|..||||
Mosquito   384 SGEQHCSGDTGKPPKPPGGKRHEPGFVLTSSLKKAPFKSSTAVVNFASNNNTINKSNFSGAGSGS 448

  Fly   359 -------NGNSEGSAGGGSTNMATTTLT---------TRP------------------------- 382
                   :|:|.||.|||.........|         |||
Mosquito   449 SSNGAGSSGSSNGSNGGGCNGSGADQRTHYCGGAGCETRPGRLRGFRHFFAKQHHQHVGLCRNQR 513

  Fly   383 -------TAPTVITTTTTT---------------------------------TVTLAKTS----- 402
                   .||..:.....|                                 |.|:.|::
Mosquito   514 YQRSSTAAAPEGLPELAETKFDESASVGQQHPYHHCHCHHAHGYHHHHHRLPTSTIVKSTQQDAK 578

  Fly   403 ------------------------------------------SPSIRVHDAALRRSNEA------ 419
                                                      .||....|.|.:.|..|
Mosquito   579 HEIVLGTGEPGPGLEPAGDAVLLPGAPPGSAATAPETGQGDCDPSALNPDPAYQFSRHAIRSTYM 643

  Fly   420 -KTLESKKRVVKMLFVLVLEFFICWTPLYVINTMVMLIGPVVYEYVDYTAISFLQLLAYSSSCCN 483
             |::|:||:|::||||:::|||:||.||:::||:.:.....||:||:.:.|:.:||:||.|||||
Mosquito   644 DKSIEAKKKVIRMLFVIIVEFFVCWAPLHILNTVYLYSPTFVYQYVNSSGIALVQLMAYISSCCN 708

  Fly   484 PITYCFMNASFRRAFVDTFKGLPWRRG-------AGASGGVGGAAGGGL------SASQAGAGPG 535
            ||||||||..||:||:..|.....|..       |.::|.:.||.....      :.:|:||
Mosquito   709 PITYCFMNRRFRQAFLGVFSCYRNRMPICCCFCCASSNGPMEGAESKAAAYLRQNTINQSGA--- 770

  Fly   536 AYASANTNISLNPGLA-MGMG 555
              ...|:::|.|..|. :|.|
Mosquito   771 --ERNNSDMSGNDSLVYVGRG 789

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D3	NP_001097023.1	7tm_GPCRs	112..498	CDD:475119	194/576 (34%)
		TM helix 1	114..138	CDD:320334	14/23 (61%)
		TM helix 2	147..169	CDD:320334	17/21 (81%)
		TM helix 3	185..207	CDD:320334	13/21 (62%)
		TM helix 4	230..246	CDD:320334	5/15 (33%)
		TM helix 5	274..297	CDD:320334	9/22 (41%)
		TM helix 6	429..451	CDD:320334	11/21 (52%)
		TM helix 7	466..491	CDD:320334	16/24 (67%)
LOC1270512	XP_061518622.1	None