Protein Alignment CCKLR-17D3 and prlhr

DIOPT Version :10

• Sequence 1: NP_001097023.1
• Gene: CCKLR-17D3 / 32864
• FlyBaseID: FBgn0030954
• Length: 584
• Species: Drosophila melanogaster
• Sequence 2: XP_002940396.1
• Gene: prlhr / 100497660
• XenbaseID: XB-GENE-994391
• Length: 343
• Species: Xenopus tropicalis
• Alignment Length: 434
• Identity: 105/434 - (24%)
• Similarity: 167/434 - (38%)
• Gaps: 129/434 - (29%)

  Fly    93 SPSPSSTPASSSSTS---TGMPV------WLIPSYSMILLFAVLGNLLVISTLVQNRRMRTITNV 148
            |.:.|..||.:|::|   .|:.:      .:||.||:::...:.||.|:|..:.:.::|..:||.
 Frog     7 STTQSLFPAMASNSSQQFMGLQLIHSYKALIIPCYSLVVFTGIFGNYLLIYVICRTKKMHNVTNF 71

  Fly   149 FLLNLAISDMLLGVLCMPVTLVGTL-LRNFIFGEFLCKLFQFSQAASVAVSSWTLVAISCERYYA 212
            .:.|||.||||:...|:|:||.... .|.::||.|||......|..:|.||.:||..|:.:||:|
 Frog    72 LVGNLAFSDMLMCATCVPLTLAYVFEPRGWVFGHFLCYFVFLMQPVTVYVSVFTLTVIAVDRYHA 136

  Fly   213 ICHPLRSRSWQTISHAYKIIGFIWLGGILCMTPIAVFSQLIPTSRPGYCKCREFWPDQGYE---L 274
            ..:|||.|  .||.....|:..|||...|...|....:..:...:..:..|.|||  .|.|   |
 Frog   137 TVYPLRRR--LTIPTCAYILAGIWLLSCLMAAPALAHTYHVEFPQLDFSICEEFW--FGMEKKRL 197

  Fly   275 FYNILLDFLLLVLPLLVLCVAYILITRTLYVGMAKDSGRILQQSLPVSATTAGGSAPNPGTSSSS 339
            .|......|...||.:::.::|:.|:       .|...|::                 ||
 Frog   198 AYAYSTLILTYALPFIIIALSYLRIS-------VKLKNRVV-----------------PG----- 233

  Fly   340 NCILVLTATAVYNENSNNNNGNSEGSAGGGSTNMATTTLTTRPTAPTVITTTTTTTVTLAKTSSP 404
                            |..|..:|
 Frog   234 ----------------NITNVQAE----------------------------------------- 241

  Fly   405 SIRVHDAALRRSNEAKTLESKKRVVKMLFVLVLEFFICWTPLYVINTMVMLIGPVVYEYVDYTAI 469
                .|.|.|           |:..::|.::|..|.:||.||::.|.|    ..:....:|....
 Frog   242 ----WDRARR-----------KKTFRLLVLVVGAFGMCWLPLHIFNIM----KDIDIHLIDKQYF 287

  Fly   470 SFLQL----LAYSSSCCNPITYCFMNASFRRAFVDTFKGLPWRR 509
            :.:||    ||..|:|.|.:.|.:::.|||......|.   |:|
 Frog   288 NLVQLLCHWLAMMSACTNSLLYAWLHDSFRGELKKMFL---WKR 328

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D3	NP_001097023.1	7tm_GPCRs	112..498	CDD:475119	95/399 (24%)
		TM helix 1	114..138	CDD:320334	8/23 (35%)
		TM helix 2	147..169	CDD:320334	10/21 (48%)
		TM helix 3	185..207	CDD:320334	7/21 (33%)
		TM helix 4	230..246	CDD:320334	5/15 (33%)
		TM helix 5	274..297	CDD:320334	5/22 (23%)
		TM helix 6	429..451	CDD:320334	7/21 (33%)
		TM helix 7	466..491	CDD:320334	8/28 (29%)
prlhr	XP_002940396.1	7tmA_PrRP_R	35..320	CDD:320516	95/393 (24%)
		TM helix 1	36..62	CDD:320516	8/25 (32%)
		TM helix 2	69..94	CDD:320516	13/24 (54%)
		TM helix 3	108..138	CDD:320516	11/29 (38%)
		TM helix 4	149..170	CDD:320516	6/20 (30%)
		TM helix 5	196..225	CDD:320516	7/35 (20%)
		TM helix 6	245..275	CDD:320516	12/44 (27%)
		TM helix 7	288..313	CDD:320516	8/24 (33%)