Protein Alignment CCKLR-17D3 and XB994602

DIOPT Version :10

• Sequence 1: NP_001097023.1
• Gene: CCKLR-17D3 / 32864
• FlyBaseID: FBgn0030954
• Length: 584
• Species: Drosophila melanogaster
• Sequence 2: XP_002940541.3
• Gene: XB994602 / 100497124
• XenbaseID: XB-GENE-994603
• Length: 364
• Species: Xenopus tropicalis
• Alignment Length: 391
• Identity: 91/391 - (23%)
• Similarity: 151/391 - (38%)
• Gaps: 118/391 - (30%)

  Fly   115 IPSYSMILLFAVLGNLLVISTLVQNRRMRTITNVFLLNLAISDMLLGVLCMPVTLVGTL-LRNFI 178
            ||.|::::..|.|||..:|..:...:::...||..:.|||::|:::.:.|:|:|..... .|.::
 Frog    35 IPIYALLVTVACLGNCALILLIALTKKLHNTTNFLIGNLALADLVMCIFCVPLTASYAFENRGWL 99

  Fly   179 FGEFLCKLFQFSQAASVAVSSWTLVAISCERYYAICHPLRSRSWQTISHAYKIIGFIWLGGILCM 243
            ||||:|......|||:|.||..:|.||:.:||..:.:|:|.|.  .......|:..:||..|...
 Frog   100 FGEFMCHFVTLMQAATVCVSVLSLTAIAVDRYVVVVYPIRRRI--GCRSCIYIVSLVWLVSIGIS 162

  Fly   244 TPIAVFSQLIPTSRPGY--CKCREFWPDQGYE-LFYNILLDFLLLVLPLLVLCVAYILITRTLYV 305
            .|....:..:.....|:  ..|.|||.:|..: |.|:..|..|..:|||..:.::|..|
 Frog   163 MPTFFHTHYLDLKSAGHDMIICEEFWRNQEKQRLLYSCSLLLLYYMLPLSAITISYCAI------ 221

  Fly   306 GMAKDSGRILQQSLPVSATTAGGSAPNPGTSSSSNCILVLTATAVYNENSNNNNGNSEGSAGGGS 370
                                                        .|:
 Frog   222 --------------------------------------------AYH------------------ 224

  Fly   371 TNMATTTLTTRPTAPTVITTTTTTTVTLAKTSSPSIRVHDAALRRSNEAKTLESKKRVVKMLFVL 435
                                       |.|.:.|....|       |:.|..:.|::..:||.:.
 Frog   225 ---------------------------LRKRNVPGATSH-------NQDKWSKKKQKTFRMLSIS 255

  Fly   436 VLEFFICWTPLYVINTMVMLIGPVVYEY--VDYTAISFLQ----LLAYSSSCCNPITYCFMNASF 494
            |:.|.|||.||.::|    ||..:..|:  :|...|:.:|    |:|.||:|.||..|..::..|
 Frog   256 VMAFGICWLPLQILN----LIRDIDEEFAILDKNYINVIQVTCHLIAMSSACYNPFIYASLHDKF 316

  Fly   495 R 495
            |
 Frog   317 R 317

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D3	NP_001097023.1	7tm_GPCRs	112..498	CDD:475119	91/391 (23%)
		TM helix 1	114..138	CDD:320334	8/22 (36%)
		TM helix 2	147..169	CDD:320334	7/21 (33%)
		TM helix 3	185..207	CDD:320334	9/21 (43%)
		TM helix 4	230..246	CDD:320334	4/15 (27%)
		TM helix 5	274..297	CDD:320334	7/22 (32%)
		TM helix 6	429..451	CDD:320334	9/21 (43%)
		TM helix 7	466..491	CDD:320334	10/28 (36%)
XB994602	XP_002940541.3	7tm_GPCRs	32..320	CDD:475119	91/391 (23%)
		TM helix 1	34..58	CDD:320516	8/22 (36%)
		TM helix 2	67..89	CDD:320516	7/21 (33%)
		TM helix 3	106..128	CDD:320516	9/21 (43%)
		TM helix 4	149..165	CDD:320516	4/15 (27%)
		TM helix 5	196..219	CDD:320516	7/22 (32%)
		TM helix 6	249..271	CDD:320516	10/25 (40%)
		TM helix 7	288..313	CDD:320516	9/24 (38%)