DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CCKLR-17D3 and cckar

DIOPT Version :9

Sequence 1:	NP_001097023.1	Gene:	CCKLR-17D3 / 32864	FlyBaseID:	FBgn0030954	Length:	584	Species:	Drosophila melanogaster
Sequence 2:	XP_017945081.1	Gene:	cckar / 100492455	XenbaseID:	XB-GENE-992615	Length:	432	Species:	Xenopus tropicalis

Alignment Length:	447	Identity:	155/447 - (34%)
Similarity:	222/447 - (49%)	Gaps:	92/447 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   118 YSMILLFAVLGNLLVISTLVQNRRMRTITNVFLLNLAISDMLLGVLCMPVTLVGTLLRNFIFGEF 182
            ||:|.|.:||||.|||:.|::|:||||:||:|||:||:||::|.:.|||.||:..|||:||||..
Frog    52 YSLIFLLSVLGNSLVIAVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFTLIPNLLRDFIFGSA 116

  Fly   183 LCKLFQFSQAASVAVSSWTLVAISCERYYAICHPLRSRSWQTISHAYKIIGFIWLGGILCMTPIA 247
            :||...:....||:||::.|||||.|||.|||.||:||.|||.|||.|:|...|......|:|..
Frog   117 VCKAATYFMGISVSVSTFNLVAISLERYSAICKPLQSRVWQTKSHALKVIAATWCLSFAIMSPYP 181

  Fly   248 VFSQLIPTSR---PGYCKCREFWPDQGYELFYNILLDFLLLVLPLLVLCVAYILITRTLYVGMAK 309
            ::|.|:|.::   .....||..||....:..:.:.|..:|.::|.:|:.:||.||:..||.|:..
Frog   182 IYSTLVPLNKIQNRTANMCRLLWPSDLTQQSWYVFLLLILFLVPGIVMTIAYGLISMELYRGIKF 246

  Fly   310 DSGRILQQSLPVSATTAGGSAPNPGTSSSSNCILVLTATAVYNENSNNNNGNSEGSAGGGSTNMA 374
            :..:..::|..:                                 |:|...|.:|        ..
Frog   247 EMSQRKERSSSI---------------------------------SSNQFKNGDG--------CY 270

  Fly   375 TTTLTTRPTAPTVITTTTTTTVTLAKTSSPSIRVHDAA----LRRSNEAKTLESKKRVVKMLFVL 435
            ..::..|                 .|.....:..|.:|    :|.::.|..|.:||||::||.|:
Frog   271 LQSIKKR-----------------KKLEMHQLSSHHSAKIERVRSNSSAANLMAKKRVIRMLIVI 318

  Fly   436 VLEFFICWTPLYVINTM---------VMLIGPVVYEYVDYTAISFLQLLAYSSSCCNPITYCFMN 491
            |:.|||||||::..|..         :.|.|         ..|||:.||:|:|:|.|||.|||||
Frog   319 VILFFICWTPVFSANAWRAFDTDSADISLSG---------VPISFIHLLSYTSACVNPIIYCFMN 374

  Fly   492 ASFRRAFVDTFKGLPWRRGAGASGGVGGAAGGGLSASQAGAGPGAYAS--ANTNISL 546
            ..||..|:.||.... .|||.....|.|.      |.:.|...||..|  ..|||||
Frog   375 KRFRMGFLATFTCCS-SRGAQGRRMVPGV------ADEEGRTTGASLSRYTYTNISL 424

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D3	NP_001097023.1	7tm_4	120..>244	CDD:304433	67/123 (54%)
CCKLR-17D3	NP_001097023.1	7tm_1	128..487	CDD:278431	124/374 (33%)
cckar	XP_017945081.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	233	1.000	Domainoid score	I2342
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	263	1.000	Inparanoid score	I3000
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1042780at2759
OrthoFinder	1	1.000	-	-		FOG0001992
OrthoInspector	1	1.000	-	-		mtm9563
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1306
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.060