Protein Alignment CCKLR-17D3 and LOC100489992

DIOPT Version :10

• Sequence 1: NP_001097023.1
• Gene: CCKLR-17D3 / 32864
• FlyBaseID: FBgn0030954
• Length: 584
• Species: Drosophila melanogaster
• Sequence 2: XP_002941889.1
• Gene: LOC100489992 / 100489992
• XenbaseID: XB-GENE-29079991
• Length: 414
• Species: Xenopus tropicalis
• Alignment Length: 392
• Identity: 106/392 - (27%)
• Similarity: 173/392 - (44%)
• Gaps: 122/392 - (31%)

  Fly   114 LIPSYSMILLFAVLGNLLVISTLVQNRRMRTITNVFLLNLAISDMLLGVLCMPVTLVGTLLRNFI 178
            ||.:||:|::.::.||:||...:::|:||.:.|::|::|||:||:::.:|..|.|||..:...::
 Frog    75 LIVAYSVIIVMSLFGNMLVCHVVMKNKRMHSATSLFIVNLAVSDIMITLLNTPFTLVRFVNSTWV 139

  Fly   179 FGEFLCKLFQFSQAASVAVSSWTLVAISCERYYAICHPLRSRSWQTISHAYKIIGFIWLGGILCM 243
            ||:.:|.:.:|.|..|:.||:.||.||:.:|:..|.:||:.|  .::|.....|.|||:......
 Frog   140 FGKEMCHISRFVQYCSLHVSTLTLTAIALDRHQVILNPLKPR--MSLSKGVLCISFIWVMATCFS 202

  Fly   244 TPIAVFSQLIPTSRPGYCK------CREFWPDQGYELF--YNILLDFLLL-VLPLLVLCVAYILI 299
            .|.|::.:|.   |..|.:      |...:|:.. :||  |..|..|||| :||||::.:||..:
 Frog   203 LPHAIYQKLF---RYNYRENKVRSLCIPDFPEPS-DLFWKYLDLSTFLLLYLLPLLIITIAYSRL 263

  Fly   300 TRTLYVGMAKDSGRILQQSLPVSATTAGGSAPNPGTSSSSNCILVLTATAVYNENSNNNNGNSEG 364
            .:.|::                                                      .|:.|
 Frog   264 AKKLWM------------------------------------------------------RNAIG 274

  Fly   365 SAGGGSTNMATTTLTTRPTAPTVITTTTTTTVTLAKTSSPSIRVHDAALRRSNEAKTLESKKRVV 429
            .                      |||....|                  .|.|       ||:.:
 Frog   275 D----------------------ITTEQYIT------------------HRKN-------KKKSI 292

  Fly   430 KMLFVLVLEFFICWTPLYVINTMVMLIGPVVYEYVDYTAISF-LQLLAYSSSCCNPITYCFMNAS 493
            |||.::|:.|.:||.||   |..|:||..:..:  ...|:.| |...|.||:|.||..||::|.|
 Frog   293 KMLVLVVVVFAVCWFPL---NCYVVLISSLGIK--TKNALYFALHWFAMSSTCYNPFIYCWLNES 352

  Fly   494 FR 495
            ||
 Frog   353 FR 354

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D3	NP_001097023.1	7tm_GPCRs	112..498	CDD:475119	106/392 (27%)
		TM helix 1	114..138	CDD:320334	9/23 (39%)
		TM helix 2	147..169	CDD:320334	8/21 (38%)
		TM helix 3	185..207	CDD:320334	9/21 (43%)
		TM helix 4	230..246	CDD:320334	4/15 (27%)
		TM helix 5	274..297	CDD:320334	13/25 (52%)
		TM helix 6	429..451	CDD:320334	9/21 (43%)
		TM helix 7	466..491	CDD:320334	11/25 (44%)
LOC100489992	XP_002941889.1	7tmA_GPR83	73..357	CDD:320511	106/392 (27%)
		TM helix 1	74..100	CDD:320511	9/24 (38%)
		TM helix 2	107..132	CDD:320511	11/24 (46%)
		TM helix 3	145..175	CDD:320511	11/29 (38%)
		TM helix 4	186..207	CDD:320511	5/20 (25%)
		TM helix 5	237..266	CDD:320511	12/28 (43%)
		TM helix 6	286..316	CDD:320511	14/39 (36%)
		TM helix 7	325..350	CDD:320511	11/24 (46%)